טיפול חדשני במטופלים עם ALS באמצעות Hepatocyte Growth Factor- היבטים פרמקודינמיים, בטיחות ונסבלות
שימוש במידזולם לטיפול באי שקט חריף באנשים מבוגרים עם דמנציה
האם טיפול כימותרפי מסייע עם GEMOX משפר תוצאים עבור מטופלים עם סרטן מקומי בדרכי המרה?
ניבוי הסיכון להתפתחות אי ספיקת לב בתוך עשר שנים באוכלוסיה הכללית
השפעת גיל המעבר על אבחנה של פוליפ ברירית הרחם
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BCL-2 Inhibitor. Venetoclax 10, 50, 100 mg. F.C. TABS.: Dosage should be ajust. individ. See lit.
Tmt. of pts. with Chron. Lymphoc. Leukem./Small Lymphoc. Lymphoma with or without 17p deletion, who have received at least one prior ther.
Acute Myeloid Leukem.: in comb. with a hypomethylating agent/comb. with low dose cytarabine is indicated for newly diagnosed pts. with AML who are ineligible for intensive chemother.
C/I: Concom. use with strong CYP3A inhib. at init. and during ramp-up phase is contraind. in pts. with CLL/SLL due to the potent. for incr. risk of tumor lysis syndr. Concom. use with St. John’s wort.
Antihistamine. Dimethindene Maleate 1 mg/ml. ORAL DROPS: 20 ml x 1 mg/ml (0.05
mg/drop). 20-40 drops 3 x dly. Child:
about 0.1 mg/kg bdy wt. 1 mth-1 yr:
3-10 drops 3 x dly, 1-3 yrs: 10-15 drops
3 x dly; 3-12 yrs: 15-20 drops 3x dly.
Prurit., allerg. conds.
Antibacterial, Antifungal, Corticosteroid. Gramicidin 0.25 mg/g, Neomycin Sulphate 2.5 mg/g, Nystatin 100000 IU/g, Triamcinolone 1 mg/g. CREAM: 5, 15 g. Apply 2-3 x dly.
See lit.
Allerg. and infect. dermatit., eczema,
cutan. candidiasis, anogenital prurit.
C/I: T.B., herpes simplex, vaccinia,
varicella, lesions not suscept. to nystatin.
Cephalosporins. Cephalexin (as monohydrate) 500 mg. CAPS: 10, 20 x 500 mg. 1-4 g per
day in div. doses. Child: 25-50 mg/kg
bdy. wt. dly. in div. doses.
Infects. due to cephalexin suscept. organ.
C/I: Hypersens. to cephalexin. See lit.
Analgesic, Antihistamine, Antipyretic, Antitussive, Decongestant. Chlorpheniramine Maleate 2 mg, Dextromethorphan HBr 10 mg, Paracetamol 500 mg, Pseudoephedrine HCl 25 mg. CAPLET.: 10, 16, 20. Adult. & child. over 12
yrs. of age: 1-2 capl. before bdtm. See
Lit.
For the symptom.relief of cold, cough,
nasal congest. accompan. by fever and
pain, for tmt. at night.
C/I: Hypersens. to the act. ingred.or
other antihistamin., decong.
Pregn., lact. Concom. use with: MAOIs, or
within 14 d. of stop. tmt. with them),
SSRIs, decongestant.; addit. meds. that
contain antihistamin., other cough &cold
meds., β-block.; relief of chron. cough;
Concom. use with other paracetamol
contain. meds.; Pts. who suffer from the
follow. dis. or cond.: severe hypertens.,
heart/vascular dis., severe hep./ren. dis.,
hyperthyroidism, glaucoma, prostate
gland dis., a cough accompan. by excess.
phlegm or that lasts long, dispnea,
asthma, pulmon. dis., diabetes. See lit.
NSAID. Piroxicam (as beta-cyclodextrin) 20 mg. TABS: 4, 10, 20, 30. 20 mg dly. Elderly: 10
mg may be necess. with limited durat.
Pain, inflamm. conds. (rheum. arthrit.,
osteoarthrit.), ankylos. spondylit., musc.-
skeletal disords., post-op. pain, prim.
dysmenorrh. See lit.
C/I: Hypersens., gastro-intest. ulc.,
gastrit., dyspep., severe hepat./ren. dis.,
severe heart fail., severe hypertens.,
blood dis. or hemorrh. diathesis. Pregn.,
lact. See lit & intro at start of sec.
Antibacterial, Antifungal, Corticosteroid. Gramicidin 0.25 mg/g, Neomycin Sulphate 2.5 mg/g, Nystatin 100000 IU/g, Triamcinolone 1 mg/g. OINT.: 5, 15 g. Apply 2-3 x dly.
See lit.
Allerg. and infect. dermatit., eczema,
cutan. candidiasis, anogenital prurit.
C/I: T.B., herpes simplex, vaccinia,
varicella, lesions not suscept. to nystatin.
Analgesic, Antipyretic, Opioid. Caffeine 50 mg, Codeine Phosphate 15 mg, Paracetamol 500 mg. CAPLETS: 12, 24. 1 caplet 3-4 x dly.
Pain, fever, cough with pain.
Other Anti-Dementia Drugs. Ginkgo Biloba 35-67:1. F.C. TABS.:15. Adults≥ 18 yrs. 1 tab.×2 d. Vertigo, adjuvant tinnitus tmt.: 1 tab.×2 d. When taken once dly., the F. C. TAB. should be taken in the morn. Dementia syndr.: Duration of the tmt. should last for at least 8 wks. See lit.
For the symptom. tmt. of mental losses due to organic brain syndr. within the framework of a general therap. concept for dementia syndr. having as major sympt.: Deficient memory, disturban. of concentr. , depress. mood, dizziness, tinnitus and headache. Vertigo of vascular and involutional origin.- Adjuvant tmt. in case of tinnitus of vascular and involutional origin. See lit.
C/I: Hypersens., preg.
NSAID. Diclofenac Sodium 100 mg. S.R. TABS: 10, 20. 1 tab. dly. (to be
swallowed whole) with or aft. meals.
Not for child. See lit.
Analgesic, anti-inflammatory.
C/I: Last trimest. pregn., known
hypersens. to ingreds./other NSAIDs,
stomach/intest. probl. after taking
NSAIDs, severe hepat., ren., card. fail., etc
see lit.
Protease Inhibitors. Darunavir 800 mg. F.C. TABS.:30. 800 mg×1/d admin. every day at the same time, and always with 100 mg of ritonavir with food. See lit.
Indicated in co-admin.with 100 mg ritonavir and with other antiretrov. agents, for the tmt. of HIV-1infec. for pts. over 18 yrs. of age.
C/I: Hypersensitivity to active substance or to any of its excipients. Pts. under 18 yrs. old age. For pts. with hep. impair., addit. blood tests may be required.
Corticosteroid, LABA, Long-acting Muscarinic Receptor Antagonist. Fluticasone Furoate 92 mcg, Umeclidinium Bromide 65 mcg, Vilanterol (as trifenatate) 22 mcg. INHALAT. PWDR., PRE-DISPENS.: 1×14, 30 doses. Applied once dly. See lit.
Long-term, once-dly., maintenan. tmt. of airflow obstruct. in pts. with COPD, includ. chron. bronchit. and/or emphysema.
Indicated to reduce exacerbat. of COPD in pts. with a history of exacerbat.
Important Limitations of Use: NOT indicat. for the relief of acute bronchospasm or for the tmt. of asthma.
C/I: Hypersens.
Antiretrovirals. Bictegravir 50 mg, Emtricitabine 200 mg, Tenofovir Alafenamide 25 mg. F.C. TABS.: 30. 1 tab×1/d with/without
food. If the patient misses a dose
within 18 hours of the time it is
usually taken, the patient should take
the drug as soon as possible and
resume the normal dosing schedule.
If a patient misses a dose by more
than 18 hours, the patient should not
take the missed dose and simply
resume the usual dosing schedule.
If the patient vomits within 1 hour of
taking the drug another tablet should
be taken. If a patient vomits more
than 1 hour after taking the drug they
do not need to take another dose of
the drug until the next regularly
scheduled dose.
Treatment of adults infected with human
immunodeficiency virus-1 (HIV-1) without
present or past evidence of viral resistance
to the integrase inhibitor class,
emtricitabine or tenofovir.
C/I: Hypersens.
Co-admin. with rifampicin and St John’s
Wort (Hypericum perforatum).
Phosphodiesterase-4 Enzyme Inhibitor. Crisaborole 2% W/W. OINT.: 2.5, 30, 60, 100 g. Should be applied twice dly. to affected areas.
The drug is for topical use only and not for ophthalm., oral, or intravag. use.
Topical tmt. of mild- moder. atopic dermatit. in pts. 2 yrs. of age and older.
C/I: Hypersens.
Lincosamide, Peroxides. Benzoyl Peroxide (as Hydrous) 5% w/w, Clindamycin Phosphate 1% w/w. GEL: 45gr. Applied once daily at the even. 2-5 wks. may pass until the effect of the medicine will be noticed.
Mild to moderate acne vulgaris, particularly inflammatory lesions.
C/I: Hypersens. to the active substance. or lincomycin.
