Immunomodulator. Lenalidomide 5, 10, 15, 25 mg.
CAPS.:7, 21. Dosage must be ajust. individ.
Previous. untreated multip. myelom. (MM) in adult pts. who are not eligible for transplant.
In comb. with dexamethasone tmt. of multip. myeloma pt. who have received at least one prior ther.
Pts. with transfuse. -dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) assoc. with a deletion 5q abnormal. with /without additional cytogen. abnormalit.
The tmt. of adults pts. with relaps. and/or refract. mantle cell lymphom. (MCL).
C/I: Hypersens. Blood donation during the therapy and for 4 wks. after discont. of the ther.
Women of child bear. potent. (WOCBP): two reliable forms of contracep. are necessary during the tmt. of this drug. WOCBP should postpone the plan. of the preg. by 4 wks. after discont. of the ther.
Breastfeed. should be discont. for 4 wks. after discont. of the ther.
Males: Donation of the semen, during ther. and short discont. The donation is allowed 4 wks. after discont. of the ther. Male pts. should use a reliable contracep. during the ther. in every sexual intercourse.

Analgesic, Antipyretic. Paracetamol 500 mg.
EFFERVESC. TABS.: 10, 20. The standard dosage. Adult. & child, aged 12 yrs. & older: 1-2 effervesc. tabs. dissolv. in a glass of water every 4-6 hrs. as requir. Do not exceed the dose of 8 effervesc. tabs. per 24 hrs.
Child.<12 yrs., weighing>33 kg: One effervescent tab. dissolv. in a glass of water every 4-6 hrs. as requir. Do not exceed the dose of 4 effervesc. tabs. per 24 hrs.
Not for swallow. in solid state. The effervescent tab. must be dissolv. before use. must be swallow. immediat. after dissolut. See lit.
Relief of pain & fever of different etiologies such as headache, toothache, colds, influenza, rheumatic pain and dysmenorrhea.
C/I: Hypersens.

Antibacterial. Chlorhexidine Digluconate 0.12% w/v.
BOTTLE (oromucosal sol.): 200ml, 500 ml. Oromucosal use only, not intend. for swallow.
Adult.: Mouth wash 1 min. with 15 ml ×2/d. Spit out after use. In the dental surg., the pt. should be instruct. to rinse the mouth for 1 min. prior to tmt.
For the tmt. of gingivitis, a course of about 1 mnth. is advisable although some variat. in response is to be expected. In the case of aphthous ulcer. & oral candidal infect. tmt. should be cont. for 48 hrs. after clinic. resolution.
For the tmt. of dental stomatitis, the dentures should be cleansed and soaked in the mouthwash for 15 min. twice dly.
Do not exceed the stated dose.
Child. & Elderl.: The normal adult dose is appropr. for elderl. pts. and child. of 12 yrs. and over.
Child. under 12 yrs. of age should not use the product.
Antibact. sol. for the disinfect. of the mouth.
As an aid to maintain. oral hygiene.
As an aid in the tmt. and prevent. of gingivitis.
Inhibit. of formation of dental plaque.
For use in aphtous ulcerat. and oral candidal infect. (e.g. denture stomatitis and thrush).
For use in a post-periodont. surg. or tmt. regimen to promote gingival healing.
C/I: Pts. with known hypersens. to Chlorhexidine.

Antibacterial. Chlorhexidine Digluconate 0.2% w/w.
TUBE (gel): 50ml. Should be appl. on moisten. toothbrush, once/twice dly. for about 1 min. Any excess should be spitted out. The mouth should not be rinsed after appl. the gel.
For the tmt. of gingivitis, a course of about one month is advisable.
When used for the manag. of aphthous ulcer. and oral candidal infec. an alternat. method of delivery may be requir. which facilitates applic. of the gel to affected areas.
This should be used once/twice dly. for about 1 min. The length of tmt. time should be decided on the basis of clinical response.
During the tmt. of denture stomatitis, the gel should be brushed thoroughly all over the dentures with 2.5 cm of gel on a moistened toothbrush, once/twice dly. for about 1 min.
Child. & Elderly pts.: The normal adult dose is appropriate for elderly pts. and child. of 12 yrs.
Child. under 12 yrs. of age should not use the product. See lit.
Oromucosal gel, a transparent gel with characteristic odour.
As an aid to maintain. oral hygiene.
As an aid in the tmt. and prevent. of gingivitis.
Inhibit. of formation of dental plaque.
For use in aphtous ulcerat. and oral candidal infect. (e.g. denture stomatitis and thrush).
For use in a post-periodont. surg. or tmt. regimen to promote gingival healing.
C/I: Pts. with known hypersens. to Chlorhexidine.

Antitubercular Agent. 4-Aminosalicylic Acid 4 g.
SACHETS (gastro-resist. granul.): 30. Adult.: 4 g (one sachet) ×3/d. The recomm. schedule is 4 g every 8 hrs., can be taken with food. Max. dly. dose is 12 g. Usual durat. of tmt. is 24 mnths.
Ped. popul.: The optimal dose regim. in child. is uncertain. Limited pharmacokin. data suggest no substant. difference betwn. adult. & child.
For infants, child. & adolesc. the dosage will be adapted to the pt’s. weight at 150 mg/kg/d, divided in two intakes. A dosing spoon is provid. to measure small doses below 4g for young child. See lit.
Indicated for use as part of an appropriate combin. regimen for multi-drug resist. tuberculos. in adult. & ped. pts. from 28 d. of age and older when an effective tmt. regimen cannot otherwise be compos. for reasons of resist. or tolerab.
Consid. should be given to official guidance on the appropriate use of antibacter. agents.
C/I: Hypersens. Severe ren. dis. Pts. with severe renal impair. should not receive GRANUPAS. Patients with severe renal dis. will accumulate the inactive acetyl metabolite of 4-aminosalicylic acid.