All the Therapeutic System Drugs
: Nucleoside & Guanosine Reverse Transcriptase Inhibitor. Lamivudine 300 mg, Abacavir 600 mg. TABS.:30. The recomm. dosage for adult.& child. over the age of 12 wt. at least 40 kg, is one tab., once dly. See lit.
Indicated in antiretrovir. comb. ther. for the tmt. of (HIV) infect. in adult., adolesc. and child. weigh. at least 25 kg.
C/I: Hypersens.
Cannabinoids. THC 0.3, 0.9, 1.5, 3, 4.5, 6 mg/drop, CBD 0.6, 0.9, 1.2, 3, 4.5, 6 mg/drop. *This product requires a license for medical cannabis.
BOTTLE. (sublingual drop.): 10gr (330 drops). Dosage should be adjust. individual.
The Israel MOH has outlined in Guidance 106 the 12 indicat. for which med. cannabis is indicated. Accord. to this guidance, the 11 indicat. for this product are:
Chemother-induc. nausea and vomit. (CINV)/ chemother induc. pain.
Metastat. cancer pain.
IBD.
Neuropath. pain.
Spastic. of MS.
Pain in Parkinson's dis.
Cachexia in AIDS.
Tourette's syndr.
Recalcitrant epilep. in adult. (Note: Accord. to Guidance 106, med. cannab. is also indic. for recalcitrant epilep. in ped. pts. but this is not an indicat. for this product)
Palliative care for termin. ill pts.
Post- traum. stress disord.
In general, the use of med. cannabis is indicated in pts. who have adequate. tried and failed convent. ther.
Please refer to Guidance 106 for details.
In addition, for an individ. pt. with a clinical. signific. med. condit. that cannot be adequate. managed by convent. ther. and which is not includ. as one of the 12 approved indicat. (eg autism, fibromyalgia), the physician can appeal to the MOH Committee for Med. Cannabis to ask for approval on an individ. exception. basis.
C/I: Prior, current/ family history (1st degr. relative) of psychos. or schizophr. or schizoaffective disord., a hist. of addict. or substance abuse (include. cannabis use disord.or addict. to alcohol), use in preg.or lact., use in pts. <18 yrs. old, bipol.disord., hypersens. to cannabis, coconut oil, palm kernel oil.
In pts. with hepat. cancer, it is recommend. not to use med. cannab. that contains THC.
See lit.
Antiretrovirals. Bictegravir 50 mg, Emtricitabine 200 mg, Tenofovir Alafenamide 25 mg. FC tabs: 30
One tab. once /d. See lit.
Tmt. of adlts infect with human immunodefic. virus-1
(HIV-1) w/o present or past evid. of viral resist. to the integrase inhib. class, emtricitabine or tenofovir
C/I:Hypersens.Co-administr. with rifampicin and St. John’s wort (Hypericum perforatum
Chemokine Receptor Antagonist. Maraviroc 150 mg, 300 mg. F.C. TABS: 10, 30, 60, 90, 180 x 150 mg,
300 mg. Depend. on interacts. With
co-admin. antiretrovir. ther. and other
medicin. prods. See lit.
In comb. with other antiretrovir. medicin.
prods., for the tmt. experienced adult pts.
infect. with only CCR5-tropic HIV-
1 detectable.
C/I: Hypersens. to active substance or to
peanut, soya or any excips., pts with
severe renal impair. or ESRD (CrCl <30
ml/ min) who take potent CYP3A4 inh.
or inducers.
DNA Polymerase Inhibitor. Ganciclovir 500 mg. VIALS: 1, 5. Adults: Initially 5mg/kg
every 12 hrs. (at a constant rate of 1
hr.), every 12 hrs. by I.V. inf. for 14 - 21
days. Maint: 6mg/kg dly. by I.V. infus. 5
days/wk. or 5 mg/kg dly. for 7 days/wk.
Only in the tmt. of CMV retinit. in
immunocompromised pts., prevent. CMV
dis. in transplant pts. at risk for CMV dis.
Anti HIV, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitabine 200 mg, Tenofovir Alafenamide 10 mg, 25 mg. F.C. TABS.:30. Dosage must be ajust. individ.
Indicated in comb. with other antiretrovir. agents for the tmt. of adult. and adolesc. (aged 12 yrs. and older with bdy. wt. at least 35 kg) infect. with human immunodeficiency virus type 1 (HIV-1).
C/I: Hypersens.
