All the Therapeutic System Drugs
Tetracycline. Doxycycline Hyclate 100 mg. CAPS: 10. Acute infects: 200 mg on first
day with food, then 100 mg dly. Acne:
100 mg dly for 6-12 wks. Malaria proph:
100 mg for 1-2 days prior to enter.
malaria area. 100 mg dly. for durat. stay.
To cont. for 3-4 wks. aft. leav.
Infects. due to tetracycl. sens. bact., acne,
prevent. malaria when other drugs not
suit. or parasites resist.
C/I: Pregn., lact., hypersens. See lit.
Tetracycline. Doxycycline Hyclate 100 mg. TABS: 7, 10, 14.
Adults: treatment of acute infections is
200 mg on the first day (single dose or
divided into two equal doses with a 12
hour interval), Maintenance dose: 100
mg/day. More severe infections: 200
mg daily. Dosage recommendations in
specific infections: See lit.
Infections due to doxycycline-susceptible
microorganisms. Prophylaxis of malaria
when other drugs are unsuitable or when the
malaria parasite is resistant to other drugs,
especially to Mefloquine.
C/I: Hypersensitivity to doxycycline, any of
its inert ingredients or to any of the
tetracyclines. Obstructive oesophageal
disorders, such as stricture or achalasia.
Pregnancy, lactation, children < 12 years.
Antiprotozoal. Miltefosine 10 mg , 50 mg. HARD CAPS.: 56×10 mg, 50 mg, 28×50 mg. Visceral leishmaniasis: Bdy. wt. 30–31 kg, 60 mg dly. Bdy. wt. 32–39 kg, 80 mg dly. Bdy. wt. 40 kg and above, 100 mg dly. An incr. to 150 mg could be consid. in pts. with a bdy. wt. > 67 kg under monitor. of the tolerabil. Cutan.
leishmaniasis: The dly. dosage for child. aged 12 yrs. and older with a bdy. wt. of at least 30 kg, adolesc./ adult. with a bdy. wt < 45 kg is 100 mg miltefosine. Pts. with a bdy. wt. > 45 kg - 150 mg miltefosine dly. Should be taken withbmeals. Dosages of 2-8 hard caps./d
should be divid. into 2-3 individ. doses to be taken either in the morn. and even. or in the morn., at noon and in the even. The duration of tmt. is 28 d. Immuno-compr. pts. may require prolong. tmt. See lit.
Tmt. of visceral Leishmaniasis caused by Leishmania donovani , in adults/adoles.≥12 yrs. of age bdy. wt. ≥30 kg (66 lbs). Tmt. of cutan. Leishmaniasis caused by Leishmania brasiliensis complex or Leishmania mexicana complex, in adults/adoles. ≥12 yrs. of age bdy. wt. ≥30 kg (66 lbs).
C/I: Hypersens. Pre-exist. severe damage of liver/kidney funct. Sjögren - Larsson Syndr. Preg. and WOCBP who do not use a reliable contracep. during and up to 5 mnths. after tmt. Women who can become preg. and have not had a preg. test. Women who can get preg. must have a urine or blood preg.
test before taking this drug.
Antiprotozoal, Biguanide. Atavaquone 62.5 mg, 250 mg, Proguanil (HCl) 25 mg, 100 mg. TABS: 12, 24. Prevent. malaria: Adult: 1
adult strength tab. dly at same time
ea. day, start. 1-2 days bef. enter.
malaria-endem. area. Cont. during stay
and for 7 days aft. return. Ped: 11-20
kg bdy wt: 1 ped. tab dly; 21-30 kg bdy
wt: 2 ped. tabs as single dly dose;
31-40 kg bdy wt: 3 ped. tabs as single
dly dose; >40 kg bdy wt: 1 adult
strength tab as single dly dose. Tmt.
acute malaria (all for 3 consec. days):
Adult: 4 adult strength tabs as single
dly dose. Ped: 11-20 kg bdy wt: 1 x
adult tab dly; 21-30 kg bdy wt: 2 x
adult tabs as single dly dose; 31-40 kg
bdy wt: 3 x adult tabs as single dly
dose; >40 kg bdy wt: 4 x adult tabs as
single dly dose.
Prevent. and tmt of malaria.