Doxycycline Hyclate

2 Drugs classified under this active ingredient

Tetracycline. Doxycycline Hyclate 100 mg.
CAPS: 10. Acute infects: 200 mg on first
day with food, then 100 mg dly. Acne:
100 mg dly for 6-12 wks. Malaria proph:
100 mg for 1-2 days prior to enter.
malaria area. 100 mg dly. for durat. stay.
To cont. for 3-4 wks. aft. leav.
Infects. due to tetracycl. sens. bact., acne,
prevent. malaria when other drugs not
suit. or parasites resist.
C/I: Pregn., lact., hypersens. See lit.

Tetracycline. Doxycycline Hyclate 100 mg.
TABS: 7, 10, 14. Adults: tmt. of acute infec. is 200 mg on the 1^st d. (single dose or divided into two equal doses with a 12 hr. interval), mainten. dose: 100 mg/d. More severe infec.: 200 mg dly. Dosage recommen. in specific infec.: See lit.
Doxycycline has been found clinic. effect. in the tmt. of a variety of infec. caused by susceptible strains of Gram-posit. and Gram-neg. bacteria and certain other microorganism.
Respirat. tract infec.: Pneumon. and other lower respirat. tract infec. due to susceptib. strains of Streptococcus pneum., Haemophilus influen., Klebsiella pneum., Moraxella catarrhalis and other organis.. Mycoplasma pneum. Tmt. of chron. bronchit., sinusit.
UTI: Infect. caused by suscept. strains of Klebsiella species, Enterobacter species, E. coli, Streptococcus faecal. and other organism.
STD: Infect. due to Chlamdyia trachomatis includ. uncomplic. urethral, endocervical or rectal infec. Non-gonococ. urethritis caused by Ureaplasma urealiticum (T-mycoplasma).
Infec. due to Calymmatobacterium granulomatis. Doxylin is an alternat. drug in the tmt. of gonorrhoea and syphilis.
Doxycycline may be expected to be useful in the tmt. of infec. such as:
Ophthalm. infec.: Tmt. of trachoma, although the infec. agent is not always eliminated, as judged by immunofluorescence. Inclus. conjunct. may be treated with oral Doxycycline alone or in comb. with topical agents.
Rickettsial infec.: Rocky Mountain spotted fever, typhus group, Q fever, Coxiella endocard.
Other infec.: Psittocosis, brucellosis (in comb. with streptomycin), cholera, bubonic plague, louse and tick-borne relaps. fever includ. stage 1 & stage 2 Lyme dis., leptospirosis, tularaemia glanders, chloroquine-resist. falciparum malaria and acute intest. amoebiasis (as an adjunct. to amoebicides). Infect. due to suscept. strains of Bacteroides species, and Listeria species.
As an alternat. drug in the tmt. of leptospirosis, gas gangrene and tetanus.
Prophylaxis in the follow. condit.: Scrub typhus, traveller's diarrhoea (enterotoxigenic E. coli), leptospirosis, malaria and cholera.
Anthrax due to Bacillus anthracis, includ. inhalat. anthrax (post exposure): to reduce the incidence or progres. of dis. follow. exposure to aerosolized Bacillus anthracis.
C/I: Hypersens. to doxycycline, any other tetracyclines. Obstruct. oesophageal disord., such as stricture or achalasia. Pregn. lact. Child.<12 yrs. See lit.