All the Therapeutic System Drugs
Penicillin, β Lactamase Inhibitors. Amoxycillin (as trihydrate) 875 mg, Clavulanic Acid (as potassium salt) 125 mg. F.C. TABS.:14. Adult. & child. ≥ 40 kg: The usual dosage: 1 tab.× 2/d, In severe cases: 1 tab. ×3/d. Should be taken with meal. See lit.|
Tmt. of the follow. infect. in adult. & child.: Acute bact. sinusit.(adequate. diagnos.) Acute otitis med. Acute exacerbat. of chron. bronchit. (adequat. diagnos.) Commun. acquired pneum. Cystitis, Pyelonephritis. Skin & soft tissue infec. in particular cellulitis, animal bites, severe dental abscess with spread. cellulitis. Bone and joint infect., in particular osteomyelitis.
C/I: Hypersens. (allergic) to amoxicillin, clavulanic acid, or other penicillin. you have ever had a severe allerg. react. to any other antibiot. e.g. (rash, facial edema, angioedema).
Pts. with history/presence of hepat. impair. jaundice while tmt. with antibiot.
Penicillin, β Lactamase Inhibitors. Amoxycillin (as trihydrate) 600 mg / 5 ml, Clavulanic Acid (as potassium) 42.9 mg / 5 ml. PWDR. FOR ORAL SUSP: 1 x 100 ml.
90/6.4 mg/kg dly in 2 div. doses. See lit.
Tmt. acute otit. med. in child > 3 mths
and <40 kg bdy wt., caused by penicillinresist.
streptococ. pneum. See lit.
C/I: Hypersens. history anaphylax.,
jaundice, hepat. impair due to
Macrolide. Azithromycin 250 mg. CAPS: 6 x 250mg.
Tmt. of STD caused by Chlamydia trachomatis: 1000 mg as a single oral dose. For all other indications in which the oral formul. is admin., the total dosage of 1500 mg should be given as 500 mg dly. for 3 d. As an alternative, the same total dose can be given over 5 d. with 500 mg given on 1st day, then 250 mg dly. on 2nd to 5th d.
Child. ≥ 45kg , adult., includ. elderly pts.: The total dose of azithromycin is 1500mg which should be given over three days (500mg once daily).
In uncomplic. genit. infec. due to Chlamydia trachomatis, the dose is 1000mg as a single oral dose.
In general, the total dose in child. is 30 mg/kg. Tmt. for ped. streptococcal pharyngit. should be dosed at a different regim.
The total dose of 30 mg/kg should be given as a single dly. dose of 10 mg/kg dly. for 3 d, or given over 5 d with a single dly. dose of 10 mg/kg on 1st d., then 5 mg/kg on 2nd -5th d.
As an alternative to the above dosing, tmt. for child. with acute otit. med. can be given as a single dose of 30 mg/kg.
For ped. streptococcal pharyngit., azithromycin given as a single dose of 10 mg/kg or 20 mg/kg for 3 d. has been shown to be effective; however, a daily dose of 500 mg must not be exceed.
For child. weighing less than 15 kg, azithromycin susp. should be measured as closely as possib. For child. weighing 15 kg or more, azithromycin susp. See lit.
Infec. caused by suscept. organis. in lower respire. tract include. bronchitis and pneum., skin&soft tissue infec., otitis med., upper respire. tract infec. includ. sinusitis & pharyngitis, tonsilitis, also in the tmt. of uncomplic. genit. infec. due to chlamydia trachomatis.
C/I: Hypersens. to azithromycin, erythromycin, any macrolide or ketolide drug. Pts. with a history of cholestatic jaundice/hep. dysfunc. assoc. with prior use of azithromycin.