All the Therapeutic System Drugs
Penicillin, β Lactamase Inhibitors. Amoxycillin (as trihydrate) 875 mg, Clavulanic Acid (as potassium salt) 125 mg. F.C. TABS.:14. Adult. & child. ≥ 40 kg: The usual dosage: 1 tab.× 2/d, In severe cases: 1 tab. ×3/d. Should be taken with meal. See lit.|
Tmt. of the follow. infect. in adult. & child.: Acute bact. sinusit.(adequate. diagnos.) Acute otitis med. Acute exacerbat. of chron. bronchit. (adequat. diagnos.) Commun. acquired pneum. Cystitis, Pyelonephritis. Skin & soft tissue infec. in particular cellulitis, animal bites, severe dental abscess with spread. cellulitis. Bone and joint infect., in particular osteomyelitis.
C/I: Hypersens. (allergic) to amoxicillin, clavulanic acid, or other penicillin. you have ever had a severe allerg. react. to any other antibiot. e.g. (rash, facial edema, angioedema).
Pts. with history/presence of hepat. impair. jaundice while tmt. with antibiot.
Penicillin, β Lactamase Inhibitors. Amoxycillin (as trihydrate) 600 mg / 5 ml, Clavulanic Acid (as potassium) 42.9 mg / 5 ml. PWDR. FOR ORAL SUSP: 1 x 100 ml.
90/6.4 mg/kg dly in 2 div. doses. See lit.
Tmt. acute otit. med. in child > 3 mths
and <40 kg bdy wt., caused by penicillinresist.
streptococ. pneum. See lit.
C/I: Hypersens. history anaphylax.,
jaundice, hepat. impair due to
Macrolide. Azithromycin (as dihydrate) 250 mg. CAPS: 6 x 250 mg. Adult.: tmt. of STD caused by Chlamydia trachomat., 1000 mg as a single oral dose. For all other indicat. in which the oral formul. is admin., the total dosage of 1500 mg should be given as 500 mg dly. for 3 d. As an alternat., the same total dose can be given over 5 d. with 500 mg given on the 1ST day, then 250 mg dly. on 2nd – 5th day.
Child.> 45kg bdy. wt. and adult., includ. elderly pts.: The total dose of azithromycin is 1500mg which should be given over 3 d. (500mg×1/d).
In uncomplic. genit. infect. due to Chlamydia trachomat., the dose is 1000mg as a sing. oral dose.
Total dose in child. is 30 mg/kg. Tmt. for ped. streptococ. pharyngit. should be dosed at a different regimen.
The total dose of 30 mg/kg should be given as a single dly. dose of 10 mg/kg dly. for 3 d., or given over 5 d. with a single dly. dose of 10 mg/kg on 1st , then 5 mg/kg on 2nd -5th d.
As an alternat. to the above dosing, tmt. for child. with acute otitis m. can be given as a single dose of 30 mg/kg.
For ped. streptococ. pharyngit., given as a single dose of 10 mg/kg or 20 mg/kg for 3 days has been shown to be effective; however, a daily dose of 500 mg must not be exceed..
For child. <15 kg, azithromycin susp. should be measured as closely as possible. For child. ≥15 kg, azithromycin susp., should be admin. accord.to the guide provided below. There is no inform. on child. less than 6 mnths. of age.
For the tmt. of sexual. transmit. dis. caused by Chlamydia trachomat., the dose is 1000 mg as a single oral dose.
Infect. caused by susceptib. organism. in lower respirat. tract includ. bronchit. and pneumon., skin and soft tissue infect., otitis media, upper respirat. tract infect. includ. sinusitis and pharyngitis, tonsilitis, also in the tmt. of uncomplicat. genit. infect. due to chlamydia trachomatis.
C/I: Hypersens.Pts. with a history of cholestat. jaundice/hep. dysfunct. assoc. with prior use of azithromycin.