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  • Macrolide
    12 Drugs classified under this drug class


    All the Drug Class Drugs

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    Azenil Capsules
    Pfizer
    RX
    partial basket chart
    Azenil Capsules

    Macrolide. Azithromycin (as dihydrate) 250 mg.
    CAPS: 6 x 250 mg. Adult.: tmt. of STD caused by Chlamydia trachomat., 1000 mg as a single oral dose. For all other indicat. in which the oral formul.  is admin., the total dosage of 1500 mg should be given as 500 mg dly. for 3 d. As an alternat., the same total dose can be given over 5 d. with 500 mg given on the 1ST day, then 250 mg dly. on 2nd – 5th day.
    Child.> 45kg  bdy. wt. and adult., includ. elderly pts.: The total dose of azithromycin is 1500mg which should be given over 3  d. (500mg×1/d).
    In uncomplic. genit. infect. due to Chlamydia trachomat., the dose is 1000mg as a sing. oral dose.
    Total dose in child. is 30 mg/kg. Tmt. for ped. streptococ. pharyngit. should be dosed at a different regimen.
    The total dose of 30 mg/kg should be given as a single dly. dose of 10 mg/kg dly. for 3 d., or given over 5 d. with a single dly. dose of 10 mg/kg on 1st , then 5 mg/kg on 2nd -5th d.
    As an alternat. to the above dosing, tmt. for child. with acute otitis m. can be given as a single dose of 30 mg/kg.
    For ped. streptococ.  pharyngit., given as a single dose of 10 mg/kg or 20 mg/kg for 3 days has been shown to be effective; however, a daily dose of 500 mg must not be exceed..
    For child. <15 kg, azithromycin susp.  should be measured as closely as possible. For child. ≥15 kg, azithromycin susp., should be admin. accord.to the guide provided below. There is no inform. on child. less than 6 mnths. of age.
    For the tmt. of sexual. transmit. dis.  caused by Chlamydia trachomat., the dose is 1000 mg as a single oral dose.
    Infect. caused by susceptib. organism. in lower respirat. tract includ. bronchit.  and pneumon., skin and soft tissue infect., otitis media, upper respirat. tract infect. includ. sinusitis and pharyngitis, tonsilitis, also in the tmt. of uncomplicat. genit. infect. due to chlamydia trachomatis.
    C/I: Hypersens.Pts. with a history of cholestat. jaundice/hep. dysfunct. assoc.  with prior use of azithromycin.

    Azenil Suspension
    Pfizer
    RX
    partial basket chart
    Azenil Suspension

    Macrolide. Azithromycin (as dihydrate) 200 mg / 5 ml.
    SUSP.: 15, 22.5ml ×250mg/5ml. Adult.: tmt. of STD caused by Chlamydia trachomat., 1000 mg as a single oral dose. For all other indicat. in which the oral formul.  is admin., the total dosage of 1500 mg should be given as 500 mg dly. for 3 d. As an alternat., the same total dose can be given over 5 d. with 500 mg given on the 1ST day, then 250 mg dly. on 2nd – 5th day.
    Child.> 45kg  bdy. wt. and adult., includ. elderly pts.: The total dose of azithromycin is 1500mg which should be given over 3  d. (500mg×1/d).
    In uncomplic. genit. infect. due to Chlamydia trachomat., the dose is 1000mg as a sing. oral dose.
    Total dose in child. is 30 mg/kg. Tmt. for ped. streptococ. pharyngit. should be dosed at a different regimen.
    The total dose of 30 mg/kg should be given as a single dly. dose of 10 mg/kg dly. for 3 d., or given over 5 d. with a single dly. dose of 10 mg/kg on 1st , then 5 mg/kg on 2nd -5th d.
    As an alternat. to the above dosing, tmt. for child. with acute otitis m. can be given as a single dose of 30 mg/kg.
    For ped. streptococ.  pharyngit., given as a single dose of 10 mg/kg or 20 mg/kg for 3 days has been shown to be effective; however, a daily dose of 500 mg must not be exceed..
    For child. <15 kg, azithromycin susp.  should be measured as closely as possible. For child. ≥15 kg, azithromycin susp., should be admin. accord.to the guide provided below. There is no inform. on child. less than 6 mnths. of age.
    For the tmt. of sexual. transmit. dis.  caused by Chlamydia trachomat., the dose is 1000 mg as a single oral dose.
    Infect. caused by susceptib. organism. in lower respirat. tract includ. bronchit.  and pneumon., skin and soft tissue infect., otitis media, upper respirat. tract infect. includ. sinusitis and pharyngitis, tonsilitis, also in the tmt. of uncomplicat. genit. infect. due to chlamydia trachomatis.
    C/I: Hypersens.Pts. with a history of cholestat. jaundice/hep. dysfunct. assoc.  with prior use of azithromycin.

    Azithromycin Teva
    Teva
    RX
    partial basket chart
    Azithromycin Teva

    Macrolide. Azithromycin 200 mg / 5 ml.
    PWDR. FOR SUSP: 15 ml, 22.5 ml. Lower
    respir. tract infects. incl. bronchit. and
    pneumon., skin and soft tissue infects.,
    otit. med., sinusit., pharyngit./tonsillit:
    Total dose: 1.5 g (500 mg) dly for 3
    days. Alt: Same total over 5 days: Day
    1: 500 mg, days 2-5: 250 mg dly. Sex.
    transmit. dis. caused by Chlamydia
    trachomat: Single oral dose: 1 g.
    Elderly: As for adults. Ren./hepat.
    impair (mild/mod.): No dose adjust.
    Child: Over 6 mths: Total dose: 30 mg/
    kg: Single dly dose: 10 mg/kg for 3
    days; over 5 days: Day 1: Single dly
    dose 10 mg/kg; days 2-5: 5 mg/kg.
    Acute otit. med: Single dose: 30 mg/
    kg. Ped. strep. pharyngit: Single dly
    dose: 10 mg/kg or 20 mg/kg for 3 days.
    Max dly dose: 500 mg. Over 45 kg:
    Adult dose. See lit.
    Infects. caused by suscept. organs: Lower
    respir. tract infects incl. bronchit.,
    pneumon., skin and soft tissue infects.,
    otit. med., upper respir. tract infects., incl.
    sinusit., pharyngit./tonsillit.,
    uncomplicat. genital infects. due to
    Chlamydia trachomat.
    C/I: History allerg. reacts to
    azithromycin/other macrolides, ingreds.
    of prep.

    Erythrocin Lactobionate I.V
    Biotis
    RX
    partial basket chart
    Erythrocin Lactobionate I.V

    Macrolide. Erythromycin 1 g/vial.
    VIAL: 1 x 1 g. 15-20 mg/kg/day. Severe
    infects: Up to 4 g.
    Bact. infects. req. I.V. tmt.
    C/I: Hypersens. to erythromycin.
    See lit.

    Karin
    Unipharm
    RX
    not in the basket chart
    Karin

    Macrolide. Clarithromycin 250 mg, 500 mg.
    TABS: 14. 1 tab 2 x dly for 7-14 days.
    Upper and lower respir. tract infects., skin
    and soft tissue infects., mycobacterium
    avium complex (MAC) infects. in AIDS, erad. helicobacter pylori infect. in comb.
    with PPI (protein pump inhibitor). C/I:
    Hypersens. to clarithromycin,
    erythromycin or any macrolide antibiot,
    pts. receiving terfenadine or astemizole.

    Klacid Pediatric Suspension
    Abbott
    RX
    not in the basket chart
    Klacid Pediatric Suspension

    Macrolide. Clarithromycin 125 mg / 5 ml.
    PED. SUSP (Granules for reconstitut):
    60 ml x 125 mg. 125 mg/5 ml 6 mths and
    older: 15 mg/kg/day in 2 div. doses.
    Upper, lower respir. tract infects., skin
    infects., mycobacter. avium, complex
    infects. in AIDS., erad. H. pylori infects. in
    comb. with other drugs, otit. media.
    C/I: Hypersens. to clarithromycin,
    erythromycin or any macrolide
    antibiotics. See lit.

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