All the Drug Class Drugs
Anti HIV, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitabine 200 mg, Tenofovir Alafenamide 10 mg, 25 mg. F.C. TABS.:30. Dosage must be ajust. individ.
Indicated in comb. with other antiretrovir. agents for the tmt. of adult. and adolesc. (aged 12 yrs. and older with bdy. wt. at least 35 kg) infect. with human immunodeficiency virus type 1 (HIV-1).
C/I: Hypersens.
Non-Nucleoside Reverse Transcriptase Inhibitors, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitavine 200 mg, Rilpivirine (as HCl) 25 mg, Tenofovir Disoproxil (as Fumarate) 245 mg. F.C. TABS: 30. Adults: 1 tab dly with
meal. Under 18 yrs: Not recommend.
Over 65 yrs: use with caution. Not
recommend. in pts. with CLcr < 50 ml/
min. See lit.
Comb. of emtricitabine, tenofovir
disoproxil fumarate and rilpivirine for use
as a complete regimen for the tmt of HIV-1
infect. in adult pts with no antiretrov. tmt
hist. and with HIV-1 RNA less than or equal
to 100,000 copies/mL at the start of ther.,
and in certain virologic. suppress. (HIV-1
RNA <50 copies/mL) adult pts on a stable
antiretrov. regimen at start of ther. in order
to replace their curr. antiretrov. tmt
regimen.
C/I: Hypersens. to act. subst. or to any
excip., co-admin. with CYP3A induc. and
gastric pH incr.: anticonvuls. –
carbamazepine, oxcarbazapine,
phenobarbital, phenytoin;
antimycobacter. – rifampin, rifapentine;
PPI – dexlansoprazole, esomeprazole,
lansoprazole, omeprazole, antoprazole,
rabeprazole; glucocorticoid systemic
dexamethasone (more than a single
dose); St. John’s wort (Hypericum
perforatum).
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Abacavir 600 mg, Lamivudine 300 mg. The recommend. dose for Adult. and child. >12 weigh. at least 40 kg, is1 tab×1/d. See lit. Tmt. of HIV infec. in adult. and in child. over the age of 12 yrs.
C/I: Hypersens.
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 100 mg, 250 mg. CAPS.: 100 ×100 mg, 40 ×250 mg.
Adults and adolecs.> 30 kg: 250-
300 mg 2 x dly.
Child 8-13 kg: 100 mg 2 x dly. 14- 21 kg: 100 mg morn. + 200 mg evening. 22-30 kg: 200 mg 2 x dly. 28—30 kg: 250 mg 2 x dly. in comb. with other anti-retrov. agent.
In combin. with anti-retroviral tmt
for HIV infected adults and children. for
use in HIV-+tive pregn. women (over 14
wks of gestat.) for prevent. of maternal-foetal HIV transmiss. and for prim. prophyl.
of HIV infect. in newborn infants.
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 109/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 200 mg / 20 ml. I.V. SOL. FOR INFUS.: 200 mg/20 ml. See lit.
Short term manag. of serious manifest. of HIV infect. in pts with AIDS unable to take
Zidovudine oral formul. for use in HIV-
+tive pregn. women (over 14 wks of
gestat.) for prevent. of maternal-foetal HIV
transmiss. and for prim. prophyl. of HIV
infect. in newborn infants. Zidovudine I.V.
should only be used when oral tmt is not
possible (except during labour and
delivery).
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 109/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 10 mg/ml. ORAL SOL.: 200 ml x 10 mg/ml.
Oral, adults and adolecs.> 30 kg: 250-
300 mg 2 x dly.
Child 9-30 kg: 9mg/kg x 2 dly. Child 4-9
kg: 12mg kg x 2 dly. Infan.<4 kg: insuff.
data. See Lit.
In combin. with anti-retroviral tmt
for HIV infected adults and children. for
use in HIV-+tive pregn. women (over 14
wks of gestat.) for prevent. of maternal-foetal HIV transmiss. and for prim. prophyl.
of HIV infect. in newborn infants.
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 109/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.