All the Active Ingredient Drugs
Non-Nucleoside Reverse Transcriptase Inhibitors. Rilpivirine 25 mg. F.C. TABS. 30. 1 tab. once dly. taken
orally with a meal.
Tmt. of HIV-1 infec. in tmt. naïve adult pts.
in comb. with other antiretroviral.
C/I: Concom. use with: anticonvulsants:
Antimycobac.: rifabutin, rifampin,
PPI: esomeprazole, lansoprazole,
omeprazole, pantoprazole, rabeprazole.
Syst. use of glucocort. : dexamethasone
(more than a sing. dose)
St. John’s wort (Hypericum perforatum).
Non-Nucleoside Reverse Transcriptase Inhibitors, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitavine 200 mg, Rilpivirine (as HCl) 25 mg, Tenofovir Disoproxil (as Fumarate) 245 mg. F.C. TABS: 30. Adults: 1 tab dly with
meal. Under 18 yrs: Not recommend.
Over 65 yrs: use with caution. Not
recommend. in pts. with CLcr < 50 ml/
min. See lit.
Comb. of emtricitabine, tenofovir
disoproxil fumarate and rilpivirine for use
as a complete regimen for the tmt of HIV-1
infect. in adult pts with no antiretrov. tmt
hist. and with HIV-1 RNA less than or equal
to 100,000 copies/mL at the start of ther.,
and in certain virologic. suppress. (HIV-1
RNA <50 copies/mL) adult pts on a stable
antiretrov. regimen at start of ther. in order
to replace their curr. antiretrov. tmt
C/I: Hypersens. to act. subst. or to any
excip., co-admin. with CYP3A induc. and
gastric pH incr.: anticonvuls. –
antimycobacter. – rifampin, rifapentine;
PPI – dexlansoprazole, esomeprazole,
lansoprazole, omeprazole, antoprazole,
rabeprazole; glucocorticoid systemic
dexamethasone (more than a single
dose); St. John’s wort (Hypericum
Antivirals for Treatment of HIV Infections. Dolutegravir 50 mg, Rilpivirine 25 mg. F.C. TABS.: 30. 1 tab. once dly., must be taken with a meal.
Missed doses: If the pt. misses a dose, the patient should take Juluca with a meal as soon as possible, provid. the next dose is not due within 12 hrs. If the next dose is due within 12 hrs, the pt. should not take the missed dose and simply resume the usual dosing schedule. See lit.
Tmt. of HIV-1 infec. in adult. who are virologically-suppressed (HIV-1 RNA <50 copies/mL) on a stable antiretrovir. regimen for at least 6 mnths. with no history of virological fail. and no known or suspect. resistance to any non-nucleoside reverse transcriptase inhib. or integrase inhib.
C/I: Hypersens. Co-admin. with: dofetilide; carbamazepine, oxcarbazepine, phenobarbital, phenytoin; rifampicin, rifapentine; PPI's (e.g.: omeprazole, esomeprazole, lansoprazole, pantoprazole, rabeprazole), system. dexamethasone, except as a single dose tmt.; St John's wort (Hypericum perforat.).