All the Active Ingredient Drugs
Nuclease Reverse Transcriptase Inhibitor. Tenofovir Disoproxil 245 mg, Emtricitabine 200 mg. FC tab.:30/90 See lit..
Tmt of HIV-1 infec.:in comb. with other anti-retroviral med. prod. for the tmt of HIV-1 infec. adlt. over 18 yrs.
Pre-expos. Proph. (PrEP): in comb. with safer sex practices for pre-expos. Proph. to reduce the risk of sex. Acquir. HIV-1 infec. in adlt at high risk.
C/I: see lit.
Antivirals for Treatment of HIV Infections. Emtricitabine 200 mg, Tenofovir Disoproxil (as fumarate) 245 mg. TABS.: 30. 1 tab×1/d with food. in case of missed a dose of the drug by more than 12 hrs. close to the time of next dose, missed dose should not be taken, simply resume the usual dosing schedule. In case of vomit. within 1 h. of taking the drug, another tab. should be taken. In case of vomit. more than 1 h. after taking this drug, re-adminst. is not necessar. See lit.
Indic. In comb. with other anti-retrov. meds. products for the tmt. of HIV-1 infect. adult. over 18 yrs. of age. In comb. with safer sex practices for preexposure prophylax. to reduce the risk of sexual. acquir. HIV-1 infec. in adult. at high risk.
C/I: Hypersens.
Non-Nucleoside Reverse Transcriptase Inhibitors, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitavine 200 mg, Rilpivirine (as HCl) 25 mg, Tenofovir Disoproxil (as Fumarate) 245 mg. F.C. TABS: 30. Adults: 1 tab dly with
meal. Under 18 yrs: Not recommend.
Over 65 yrs: use with caution. Not
recommend. in pts. with CLcr < 50 ml/
min. See lit.
Comb. of emtricitabine, tenofovir
disoproxil fumarate and rilpivirine for use
as a complete regimen for the tmt of HIV-1
infect. in adult pts with no antiretrov. tmt
hist. and with HIV-1 RNA less than or equal
to 100,000 copies/mL at the start of ther.,
and in certain virologic. suppress. (HIV-1
RNA <50 copies/mL) adult pts on a stable
antiretrov. regimen at start of ther. in order
to replace their curr. antiretrov. tmt
regimen.
C/I: Hypersens. to act. subst. or to any
excip., co-admin. with CYP3A induc. and
gastric pH incr.: anticonvuls. –
carbamazepine, oxcarbazapine,
phenobarbital, phenytoin;
antimycobacter. – rifampin, rifapentine;
PPI – dexlansoprazole, esomeprazole,
lansoprazole, omeprazole, antoprazole,
rabeprazole; glucocorticoid systemic
dexamethasone (more than a single
dose); St. John’s wort (Hypericum
perforatum).
Antiretrovirals. Elvitegravir 150 mg, Cobicistat 150 mg, Emtricitabine 200 mg, Tenofovir Disoproxil 245 mg. TABS.:30. 1 tab. ×1/d with food. If the pt. misses a dose within 18 hrs. of the time it is usual. taken, the pt. should take the drug with food as soon as possible and resume the normal dosing schedule. If a pt. misses a dose by more than 18 hrs., the pt. should not take the missed dose and simply resume the usual dosing schedule. If the pt. vomit. within 1 h of taking the drug another tab. should be taken.
C/I: Hypersens. Pts. who have prev. discount. tmt. with tenofovir disoproxil fumarate due to renal tox. , with/without reversal of the effects post-discont. Co-admin. with the follow. med. products due to the potent. for serious and/or life-threat. events or loss of virologic response and possible resist. to this drug: α-1-adrenorecep. antagon.: alfuzosin -antiarrhythmics: amiodarone, quinidine Anticonvuls.: carbamazepine, phenobarbital, phenytoin , antimycobacterials: rifampicin, ergot derivatives: dihydroergotamine, ergometrine, ergotamine. GI motil. agents: cisapride. Herb. products: St. John’s wort HMG Co-A reductase inhib.: lovastatin, simvastatin , neuroleptics: pimozide PDE-5 inhib. : sildenafil for tmt. of pulmon. arter. hypertens. Sedat./hypnotics: orally admin. midazolam, triazolam.
Nucleoside Reverse Transcriptase Inhibitor. Tenofovir Disoproxil 245 mg. F.C. TABS: 30. 1 tab dly with food.
Tmt. of (1) HIV 1 infec. adults and ped. pts.
12 yrs. of age and older in comb. with
other antiretrov.med. prod. for the tmt. of
HIV;) chron. hep. B in adults with: compen.
liver dis., with evidence of act. viral
replicat., persist. elevated (ALT) levels and
histology. evidence of act. inflam. and/or
fibrosis, decompens. liver dis.
C/I: Hypersens. concom. use of other
drgs. contain tenofovir fumarate; comb.
with drgs. contain adefovir dipivoxil;
preg. ,lact.
Nucleoside Reverse Transcriptase Inhibitor. Emtricitavine 200 mg, Tenofovir Disoproxil 245 mg. F.C. TABS: 30. 1 tab dly with
food. Child: Under 18 yrs. not
recommend.
In comb. with other antiretrovirals to
treat HIV-1 infects.
C/I: Severe ren. impair., lact.