All the Drug Class Drugs
Anti HIV, Antivirals for Treatment of HIV Infections, Antivirals/HIV, Non-Nucleoside Reverse Transcriptase Inhibitors. Rilpivirine 600 mg, 900 mg. susp. for IM. inj. Prol.Rel. 2/3 ml
One 900 mg injection /mo followed by a 600 mg inj. on the next mo. Treat. may be preceded by oral rilpirivine tabs. (lead-in ther.) to assess tolerability. See full prescr. details.
In combin. with cabotegravir inject., for tmt. of human immunodefic. virus type 1 (HIV-1) infect. in adlts. who are virolog. suppress. (HIV-1 RNA < 50 copies/mL) on a stable antiretrov. regim. w/o pres. or past evid. of viral resist. to, and no prior virolog. failure with, agents of the NNRTI and INI class.
C/I: Hypersens. Not to be co-admin. with the follow. med. products, as signif. decr. in rilpivirine plasma concentr. may occur (due to CYP3A enzyme induct.), which may result in loss of its ther. effect: anticonvuls.: carbamazepine, oxcarbazepine, phenobarbital, phenytoin,
antimycobact.: rifabutin, rifampicin, rifapentine,
syst. ude of glucocorticoid dexamethasone, except as a sgle. dose tmt.,
St John’s wort (Hypericum perforatum).