Antivirals for Treatment of HIV Infections

5 Drugs classified under this drug class

Antivirals for Treatment of HIV Infections. Emtricitabine 200 mg, Tenofovir Disoproxil (as fumarate) 245 mg.
TABS.: 30. 1 tab×1/d with food. in case of missed a dose of the drug by more than 12 hrs. close to the time of next dose, missed dose should not be taken, simply resume the usual dosing schedule. In case of vomit. within 1 h. of taking the drug, another tab. should be taken. In case of vomit. more than 1 h. after taking this drug, re-adminst. is not necessar. See lit.
Indic. In comb. with other anti-retrov. meds. products for the tmt. of HIV-1 infect. adult. over 18 yrs. of age. In comb. with safer sex practices for preexposure prophylax. to reduce the risk of sexual. acquir. HIV-1 infec. in adult. at high risk.
C/I: Hypersens.

Antivirals for Treatment of HIV Infections. Dolutegravir 50 mg, Rilpivirine 25 mg.
F.C. TABS.: 30. 1 tab. once dly., must be taken with a meal.
Missed doses: If the pt. misses a dose, the patient should take Juluca with a meal as soon as possible, provid. the next dose is not due within 12 hrs. If the next dose is due within 12 hrs, the pt. should not take the missed dose and simply resume the usual dosing schedule. See lit.
Tmt. of HIV-1 infec. in adult. who are virologically-suppressed (HIV-1 RNA <50 copies/mL) on a stable antiretrovir. regimen for at least 6 mnths. with no history of virological fail. and no known or suspect. resistance to any non-nucleoside reverse transcriptase inhib. or integrase inhib.
C/I: Hypersens. Co-admin. with: dofetilide; carbamazepine, oxcarbazepine, phenobarbital, phenytoin; rifampicin, rifapentine; PPI's (e.g.: omeprazole, esomeprazole, lansoprazole, pantoprazole, rabeprazole), system. dexamethasone, except as a single dose tmt.; St John's wort (Hypericum perforat.).

Antivirals for Treatment of HIV Infections. Emtricitabine 200 mg, Rilpivirine 25 mg, Tenofovir Alafenamide 25 mg.
FC Tab. 200/25/25 mg X 30
1 dly. with food
Tmt. of adlts. and adolesc. (aged 12 years and older with
weight of at least 35 kg) infect. with human immunodefic. virus-1 (HIV-1) without known mutat. assoc. with resist. to the non-nucleoside reverse transcriptase inhib. (NNRTI) class, tenofovir or emtricitabine and with viral load ≤ 100,000 HIV-1 RNA copies/mL
C/I:  Hypersens. Should not be co-admin. with drugs that can result in signific. decr. in rilpivirine plasma concentr. (due to cytochr. P450 [CYP]3A enzyme induct. or gastric pH incr.), which may result in loss of ther. effect of this drug includ.:
• carbamazepine, oxcarbazepine, phenobarbital, phenytoin
• rifabutin, rifampicin, rifapentine
• omeprazole, esomeprazole, dexlansoprazole, lansoprazole, pantoprazole, rabeprazole
• dexamethasone (oral and parenteral doses), except as a sgle. dose tmt.
• St. John’s wort (Hypericum perforatum)

Anti HIV, Antivirals for Treatment of HIV Infections, Antivirals/HIV, Non-Nucleoside Reverse Transcriptase Inhibitors. Rilpivirine 600 mg, 900 mg.
susp. for IM. inj. Prol.Rel. 2/3 ml
 One 900 mg injection /mo followed by a 600 mg inj. on the next mo. Treat. may be preceded by oral rilpirivine tabs. (lead-in ther.) to assess tolerability. See full prescr. details.
In combin. with cabotegravir inject., for tmt. of human immunodefic. virus type 1 (HIV-1) infect. in adlts. who are virolog. suppress. (HIV-1 RNA < 50 copies/mL) on a stable antiretrov. regim. w/o pres. or past evid. of viral resist. to, and no prior virolog. failure with, agents of the NNRTI and INI class.
C/I:  Hypersens. Not to be co-admin. with the follow. med. products, as signif. decr. in rilpivirine plasma concentr. may occur (due to CYP3A enzyme induct.), which may result in loss of  its ther. effect: anticonvuls.: carbamazepine, oxcarbazepine, phenobarbital, phenytoin,
antimycobact.: rifabutin, rifampicin, rifapentine,
syst. ude of glucocorticoid dexamethasone, except as a sgle. dose tmt.,
St John’s wort (Hypericum perforatum).

Antivirals for Treatment of HIV Infections, Combinations. Abacavir (as sulfate) 600 mg, Lamivudine 300 mg, Dolutegravir (as sodium) 50 mg.
F.C. TAB: 30. 1 tab x 1 dly. Renal impairm.:
not recom. in pts. with CLcr < 50 ml/
min. Hepatic impairm.: see lit.
Treat. of HIV infec. Adults and adolesc.
above 12 yrs weigh. at least 40 kg.
C/I: Hypersens. to dolutegravir, abacavir
or lamivudine or to any of the excip.
Co-administ. with dofetilide.