All the Active Ingredient Drugs
Antivirals for Treatment of HIV Infections. Dolutegravir 50 mg, Rilpivirine 25 mg. F.C. TABS.: 30. 1 tab. once dly., must be taken with a meal.
Missed doses: If the pt. misses a dose, the patient should take Juluca with a meal as soon as possible, provid. the next dose is not due within 12 hrs. If the next dose is due within 12 hrs, the pt. should not take the missed dose and simply resume the usual dosing schedule. See lit.
Tmt. of HIV-1 infec. in adult. who are virologically-suppressed (HIV-1 RNA <50 copies/mL) on a stable antiretrovir. regimen for at least 6 mnths. with no history of virological fail. and no known or suspect. resistance to any non-nucleoside reverse transcriptase inhib. or integrase inhib.
C/I: Hypersens. Co-admin. with: dofetilide; carbamazepine, oxcarbazepine, phenobarbital, phenytoin; rifampicin, rifapentine; PPI's (e.g.: omeprazole, esomeprazole, lansoprazole, pantoprazole, rabeprazole), system. dexamethasone, except as a single dose tmt.; St John's wort (Hypericum perforat.).
Integrase Strand Transfer Inhibitor. Dolutegravir 10, 25, 50 mg. F.C.TABS.: 30. Adults: Pts. without documented or clin. suspect. resistance to the integrase class: 50 mg × 1/d . Pts. treated. with: efavirenz, nevirapine, tipranavir/ritonavir, or rifampicin: 50 mg × 2/d. Pts. with resist. to the integrase class: 50 mg × 2/d. Adoles. 12-17 yrs w/o resistance to integrase class: 50 mg × 1/d. See lit.
in combin. with other anti-retroviral medic. products for the tmt. of HIV infect. in adults and adolescen. aged 12 yrs. and older and weighing at least 40 kg.
C/I: Hypersens., co-administ. with dofetilide.
Antivirals for Treatment of HIV Infections, Combinations. Abacavir (as sulfate) 600 mg, Lamivudine 300 mg, Dolutegravir (as sodium) 50 mg. F.C. TAB: 30. 1 tab x 1 dly. Renal impairm.:
not recom. in pts. with CLcr < 50 ml/
min. Hepatic impairm.: see lit.
Treat. of HIV infec. Adults and adolesc.
above 12 yrs weigh. at least 40 kg.
C/I: Hypersens. to dolutegravir, abacavir
or lamivudine or to any of the excip.
Co-administ. with dofetilide.
