All the Active Ingredient Drugs
Protease Inhibitors. Darunavir 75, 150, 400, 600, 800 mg. TABS: 480 x 75 mg ; 240 x 150 mg.
Tmt. HIV-1 infect. co-admin. with ritonavir
and with other antiretroviral agents in
adult pts and in tmt-experienc. pediatric
pts 6 yrs of age and older. See lit.
TABS: 60 x 400 mg, 60 x 600 mg, 30 x 800
mg.
Tmt. HIV-1 infect. in adult pts co-admin.
with ritonavir and with other antiretroviral
agents. See lit.
Tmt-naïve adults: 800 mg with 100 mg
ritonavir 1 x dly, with food. See lit.
Tmt-experience. adults: (With no
darunavir resist. assoc. subst.) 800 mg
with 100 mg ritonavir 1 x dly, with
food. See lit.
Tmt-experience. adults: (With at least 1
darunavir resist. assoc. substit.)
600 mg with 100 mg ritonavir 2 x dly,
with food. See lit.
C/I: Hypersens.; severe (Child-Pugh Class
C) hepatic impair.; Co-admin. with
ritonavir is C/I with drugs that are highly
dependent on CYP3A and drugs with
narrow therap. index.
Refer to ritonavir C/I. See lit.