Zidovudine

4 Drugs classified under this active ingredient

Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 100 mg, 250 mg.
CAPS.: 100 ×100 mg, 40 ×250 mg.
Adults and adolecs.> 30 kg: 250-
300 mg 2 x dly.
Child 8-13 kg: 100 mg 2 x dly. 14- 21 kg: 100 mg morn. + 200 mg evening. 22-30 kg: 200 mg 2 x dly. 28—30 kg: 250 mg 2 x dly. in comb. with other anti-retrov. agent. 
In combin. with anti-retroviral tmt
for HIV infected adults and children. for
use in HIV-+tive pregn. women (over 14
wks of gestat.) for prevent. of maternal-foetal HIV transmiss. and for prim. prophyl.
of HIV infect. in newborn infants.
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 10⁹/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.

Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 200 mg / 20 ml.
I.V. SOL. FOR INFUS.: 200 mg/20 ml. See lit.
Short term manag. of serious manifest. of HIV infect. in pts with AIDS unable to take
Zidovudine oral formul. for use in HIV-
+tive pregn. women (over 14 wks of
gestat.) for prevent. of maternal-foetal HIV
transmiss. and for prim. prophyl. of HIV
infect. in newborn infants. Zidovudine I.V.
should only be used when oral tmt is not
possible (except during labour and
delivery).
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 109/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.

Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Zidovudine 10 mg/ml.
ORAL SOL.: 200 ml x 10 mg/ml.
Oral, adults and adolecs.> 30 kg: 250-
300 mg 2 x dly.
Child 9-30 kg: 9mg/kg x 2 dly. Child 4-9
kg: 12mg kg x 2 dly. Infan.<4 kg: insuff.
data. See Lit.
In combin. with anti-retroviral tmt
for HIV infected adults and children. for
use in HIV-+tive pregn. women (over 14
wks of gestat.) for prevent. of maternal-foetal HIV transmiss. and for prim. prophyl.
of HIV infect. in newborn infants. 
C/I: Hypersens., abnorm. low neutrophil
counts (< 0.75 x 10⁹/L) or abnorm. low
HGB levels (less than 7.5 g/dL or 4.65
mmol/L). Oral formul.- also: newborn
infants with hyperbilirubin. requir. tmt
other than phototherapy, or with
increase. transaminase levels of over 5
times the upper limit of normal.

Nucleoside Reverse Transcriptase Inhibitor. Abacavir (as sulfate) 300 mg, Lamivudine 150 mg, Zidovudine 300 mg.
F.C. TABS: 60. 1 tab 2 x dly with or
without food. Start tmt. with the 3
components separately for first 6-8
wks then transfer to fixed comb. Child.
under 18 yrs not recommend.
Tmt. of HIV infect. in adults.
C/I: Hypersens., espec. hypersensitivity
reactions, end-stage renal dis.;
neutrophil count < 0.75 x 10^9/l or
Hg. levels < 7.5g/dl or 4.65 mmol/l.