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  • Nucleoside Reverse Transcriptase Inhibitor
    12 Drugs classified under this drug class


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    Entecavir Teva
    Teva
    RX
    not in the basket chart
    Entecavir Teva

    Nucleoside Reverse Transcriptase Inhibitor. Entecavir 0.5 mg, 1 mg.
    TABS.:30: Compens. liver dis.: Nucleoside naive pts.: 0.5 mg×1/d, with/without food. Lamivudine-refractory pts.: 1 mg ×1/d, without food. Decompens. liver dis.: 1 mg ×1/d, without food. For pts. with lamivudine-refractory hepatitis B, see lit.
    Tmt. of chronic HBV infec. in adults with: Compens. liver dis.  and evidence of active viral replic. persist. elevated serum ALT levels and histolog. evidence of active inflam. and/ or fibrosis. Decompens.  liver dis. For both compens. and decompens. liver dis. , this indic.  is based on clinical trial data in nucleoside naive pts. with HBeAg positive and HBeAg negative HBV infec.  With respect to pts. with lamivudine-refract. hepatitis B.
    C/I: Hypersens., lact.

    Rebetol
    MSD
    RX
    partial basket chart
    Rebetol

    Nucleoside Reverse Transcriptase Inhibitor. Ribavirin 200 mg.
    CAPS: 168. ≤75 kg: 1,000 mg dly; >75
    kg: 1,200 mg dly in 2 div. doses.
    In comb. with interferon Alfa-2b comb.
    (intron A) inject. for chron. hepatit. C in
    18 yrs or older with compensated liver
    dis. previous. untreated with Alfa
    interferon or foll. relapse aft. treat. with
    Alfa interferon.

    Sebivo
    Novartis
    RX
    partial basket chart
    Sebivo

    Nucleoside Reverse Transcriptase Inhibitor. Telbivudine 600 mg.
    F.C. TABS: 28 x 600 mg. 1 tab dly. See lit.
    Tmt. chron. hepatit. B in pts with
    evidence viral replicat. and active liver
    inflamm. in adults over 16 yrs.
    C/I: Hypersens.

    Tenofovir Teva
    Teva
    RX
    partial basket chart
    Tenofovir Teva

    Nucleoside Reverse Transcriptase Inhibitor. Tenofovir Disoproxil 245 mg.
    F.C. TABS: 30. 1 tab dly with food.
    Tmt. of (1) HIV 1 infec. adults and ped. pts.
    12 yrs. of age and older in comb. with
    other antiretrov.med. prod. for the tmt. of
    HIV;) chron. hep. B in adults with: compen.
    liver dis., with evidence of act. viral
    replicat., persist. elevated (ALT) levels and
    histology. evidence of act. inflam. and/or
    fibrosis, decompens. liver dis.
    C/I: Hypersens. concom. use of other
    drgs. contain tenofovir fumarate; comb.
    with drgs. contain adefovir dipivoxil;
    preg. ,lact.

    Trizivir
    GSK
    RX
    partial basket chart
    Multiple ingredients
    Trizivir

    Nucleoside Reverse Transcriptase Inhibitor. Abacavir (as sulfate) 300 mg, Lamivudine 150 mg, Zidovudine 300 mg.
    F.C. TABS: 60. 1 tab 2 x dly with or
    without food. Start tmt. with the 3
    components separately for first 6-8
    wks then transfer to fixed comb. Child.
    under 18 yrs not recommend.
    Tmt. of HIV infect. in adults.
    C/I: Hypersens., espec. hypersensitivity
    reactions, end-stage renal dis.;
    neutrophil count < 0.75 x 10^9/l or
    Hg. levels < 7.5g/dl or 4.65 mmol/l.

    Truvada
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Truvada

    Nucleoside Reverse Transcriptase Inhibitor. Emtricitavine 200 mg, Tenofovir Disoproxil 245 mg.
    F.C. TABS: 30. 1 tab dly with
    food. Child: Under 18 yrs. not
    recommend.
    In comb. with other antiretrovirals to
    treat HIV-1 infects.
    C/I: Severe ren. impair., lact.

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