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  • Hypolipidemic Agents
    24 Drugs classified under this therapeutic system


    All the Therapeutic System Drugs

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    Alsepa
    Altman
    OTC
    not in the basket chart
    Alsepa

    Omega-3 300 mg (DHA 120 mg, EPA 180 mg).
    CAPS: 210. 1 cap dly, dur.
    meal.
    Nutritional supplement.
    C/I: Hypersens.

    Alsepa Super
    Altman
    OTC
    not in the basket chart
    Alsepa Super

    Omega-3 600 mg.
    CAPS: 120. 1-3 caps dly, dur. meal.
    Nutritional supplement.
    C/I: Hypersens.

    Atozet
    MSD
    RX
    partial basket chart
    Multiple ingredients
    Atozet

    HMG-CoA Reductase Inhibitor, Lipid Modifying Agent. Ezetimibe 10 mg, Atorvastatin 10, 20, 40, 80 mg.
    F.C. TABS.: 30. Hypercholesterolaemia and/or CHD with ACS History). The pt. should be on an appropriate lipid-lower. diet and should cont. on this diet during tmt. with this drug.
    The dose range is 10/10 mg/d. through 10/80 mg/d. The typical dose is 10/10 mg ×1/d. The pt’s. low-density lipoprotein cholesterol (LDL-C) level, CHD status, and response to current cholesterol-lower. ther. should be consid. when starting ther. or adjust. the dose.
    The dose should be individual. based on the known efficacy of the various dose strengths of and the response to the current cholesterol-lower. ther. Adjust. of dose should be made at intervals of 4 wks. or more.
    HoFH: 10/10-10/80 mg dly. The drug  may be used as an adjunct to other lipid-lower. tmts. (e.g., LDL apheresis) in these pts. or if such tms. are unavailab.
    May be taken with/without food.
    Prevent. of Cardiovasc. Event: Indicat. to reduce the risk of cardiovasc. events in pts. with coron. heart dis.(CHD) and a hist. of acute coron. syndr. (ACS), either previous. treated with a statin or not.
    Hypercholesterolaemia: The drug  indicat. as adjunct. ther. to diet for use in adult. with prim. (heterozygous famil. and non-famil.) hypercholesterolaemia or mixed hyperlipidaemia where use of a comb. product is appropriate, pts. not appropriat. control. with a statin alone, pts. already treated with a statin and ezetimibe.
    Homozyg. Familial Hypercholesterolaemia (HoFH): Indicat. as adjunct. ther. to diet for use in adults with HoFH. Pts. may also receive adjunct. tmts. (e.g., low-density lipoprotein [LDL] apheresis).
    C/I: Hypersens. Preg., lact. , and in women of child-bear. potent.

    Bezafibrate 400 SR
    Medison
    RX
    full basket chart
    Bezafibrate 400 SR

    Fibrate. Bezafibrate 400 mg.
    S.R. TABS: 30. 1 tab dly in even.
    Hyperlipidem. in types 11a, 11b, III, IV, V
    where diet alone is insuffic.
    C/I: Hypersens., pregn., lact., liver/
    gallbladder dis., severe renal funct.
    disords.

    Crestor
    Astra Zeneca
    RX
    partial basket chart
    Crestor

    Statin. Rosuvastatin (as Calcium) 5, 10, 20, 40 mg.
    TABS: 28 x 5mg, 10 mg, 20 mg, 40
    mg. Not to be chewed, crushed or
    divided. May be given at any time of the
    day, with or without food. Bef. tmt.
    initiat. pt. to be on a standard
    cholesterol-lower. diet that should
    contin. dur. tmt. Individual. accord. to
    the goal of the ther. and pt.
    response. Start dose: 10 mg 1 x dly. Dose
    adjust. to 20 mg can be made after 4 wks if necess. 40 mg only in pts. with
    severe hypercholesterolem. at high CV
    risk who do not achieve their tmt. goal
    on 20 mg. Follow-up routine to be
    performed. Not recommend. for ped.
    No dos adjust. necess in elderly, or pts.
    with mild to mod. ren. impair. Hepat.
    impair. pts. with Child-Pugh scores of 8
    and 9: Assess. of ren. funct. should be
    considered.
    Prim. hypercholesterolem. (type IIa incl.
    heterozygous famil.
    hypercholesterolem.) or mixed
    dyslipidem. (type IIb) as an adjunct to
    diet when response to diet and other
    non-pharmacolog. tmts. (e.g exercise,
    wt. reduct.) is inad. Homozygous famil.
    hypercholesterolem. as an adjunct to
    diet and other lipid lower. tmts (e.g. LDL
    apheres.) or if such tmts. not approp.
    C/I: Hypersens. to rosuvastatin or to any of
    the excips.; active liver dis. incl.
    unexplain., persist. elevat. serum
    transaminases and any serum
    transaminase elevat. exceed. 3 x the
    upper limit of normal (ULN); severe ren.
    impair. (creatinine clear. <30ml/min);
    myopath. pts. receiv. concom.
    cyclosporin; pregn., lact., women of
    childbearing potential not using approp.
    contracept. measures.

    Ezecor
    Unipharm
    RX
    not in the basket chart
    Ezecor

    Cholesterol Absorption Inhibitor. Ezetimibe 10 mg.
    TABS.:30 Adult./ adolesc.(10- 17 yrs.):10mg×1/d with/without food Cholesterol-low.  diet should be init. before tmt. initiat. and contin. during the tmt.
    Prim. hypercholesterolemia: admin.with a statin or alone. As adjunct. ther.to diet for use in pts. with prim. (heterozygous famil. and non-famil.) hypercholesterolemia. Homozygous famil. hypercholesterolem.: Concom. use with a statin for use in pts. with  HoFH .Pts. may also receive adjunct. tmts. (e.g. LDL apheresis). Homozygous sitosterolem. (Phytosterolem.): pts. with homozygous famil. sitosterolem.
    C/I: Hypersens. Contom. use with statin, in pts. with hep. impair. Contom. use with  statin, in  preg./lact.


    Other therapeutic systems under Cardiovascular System

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