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  • Statin
    13 Drugs classified under this drug class


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    Atorvastatin Teva
    Teva
    RX
    partial basket chart
    Atorvastatin Teva

    Statin. Atorvastatin 10, 20, 40, 80 mg.
    F.C. TABS: 30 x 10 mg, 20 mg, 40 mg, 80
    mg. Prim. hypercholesterolem. incl.
    famil. hypercholesterolem.
    (heterozygous variant)/comb. (mixed)
    hyperlipidemia (Fredrickson types IIa,
    IIb): Initial: 10-20 mg 1 x dly. Pts. requir.
    large reduct. in LDL (>45%): 40 mg 1 x
    dly. Dos. range: 10-80 mg 1 x dly. To be
    individualiz. Homozygous famil.
    hypercholesterolem: 10-80 mg 1 x dly
    as adjuv. to other lipid-lower. tmt or if
    such tmts unavail. Heterozygous famil.
    hypercholesterolem in ped. pts (10-17
    yrs): Initial: 10 mg dly; max: 20 mg dly.
    To be individualiz. Prevent. CV/
    cerebrovasc. events: 10 mg dly. Higher
    dos. may be necessary. Hepat. insuffic:
    Perform liver tests bef. initiat. tmt, at 6
    and 12 wks aft. initiat./elevat. dose and
    periodic. (e.g. semi-annually). Ren.
    insuffic: No dose adjust. req. Elderly: As
    gen. populat.
    Hypercholesterolem: Adjuv. to diet for
    reduct. elevat. total cholesterol LDLcholesterol
    apolipoprotein B and
    triglycerides and to increase HDL
    cholesterol in pts with prim.
    hypercholesterolem. when response to
    diet and other nonpharmacolog.
    measures is inadeq; to reduce total-C and
    LDL-C in pts. with homozygous familial
    hypercholesterolem. as an adjunct to
    other lipid-lower. tmt. (e.g. LDL apheres.)
    or if such tmts are unavail. Ped. pts (10-17
    yrs): Adjuv. to diet to reduce total -C, LDL-C
    and apo B levels in boys and
    postmenarchal girls with heterozygous
    famil. hypercholesterolem. Prevent. CV
    dis./cerebrovasc. event: Adjuv. to correct.
    other risk factors such as hypertens. Pts.
    with clinic. evident coronary heart dis:
    Reduce risk of non-fatal MI; reduce risk of
    fatal and non fatal stroke; reduce risk of
    hospitalizat. for CHF; reduce risk of
    angina. Reduce risk revascular. proced.
    C/I: Hypersens., active liver dis./
    unexplained persist. elevats. serum
    transaminases exceeding 3 x upper limit
    of normal; myopath., pregn./lact.;
    women of childbear. potent. not using
    approp. contracept. measures.

    Crestor
    Astra Zeneca
    RX
    partial basket chart
    Crestor

    Statin. Rosuvastatin (as Calcium) 5, 10, 20, 40 mg.
    TABS: 28 x 5mg, 10 mg, 20 mg, 40
    mg. Not to be chewed, crushed or
    divided. May be given at any time of the
    day, with or without food. Bef. tmt.
    initiat. pt. to be on a standard
    cholesterol-lower. diet that should
    contin. dur. tmt. Individual. accord. to
    the goal of the ther. and pt.
    response. Start dose: 10 mg 1 x dly. Dose
    adjust. to 20 mg can be made after 4 wks if necess. 40 mg only in pts. with
    severe hypercholesterolem. at high CV
    risk who do not achieve their tmt. goal
    on 20 mg. Follow-up routine to be
    performed. Not recommend. for ped.
    No dos adjust. necess in elderly, or pts.
    with mild to mod. ren. impair. Hepat.
    impair. pts. with Child-Pugh scores of 8
    and 9: Assess. of ren. funct. should be
    considered.
    Prim. hypercholesterolem. (type IIa incl.
    heterozygous famil.
    hypercholesterolem.) or mixed
    dyslipidem. (type IIb) as an adjunct to
    diet when response to diet and other
    non-pharmacolog. tmts. (e.g exercise,
    wt. reduct.) is inad. Homozygous famil.
    hypercholesterolem. as an adjunct to
    diet and other lipid lower. tmts (e.g. LDL
    apheres.) or if such tmts. not approp.
    C/I: Hypersens. to rosuvastatin or to any of
    the excips.; active liver dis. incl.
    unexplain., persist. elevat. serum
    transaminases and any serum
    transaminase elevat. exceed. 3 x the
    upper limit of normal (ULN); severe ren.
    impair. (creatinine clear. <30ml/min);
    myopath. pts. receiv. concom.
    cyclosporin; pregn., lact., women of
    childbearing potential not using approp.
    contracept. measures.

    Lipitor
    Pfizer
    RX
    partial basket chart
    Lipitor

    Statin. Atorvastatin (as calcium) 10, 20, 40, 80 mg.
    F.C. TABS: 30 x 10 mg, 20 mg. Init: 10-20-
    mg 1 x dly. Pts requir. larger reduct. in
    LDL (more than 45%) may be started
    at 40 mg 1 x dly. Adjust. dose at
    intervals of 4 wks or more. Max. dose:
    80 mg 1 x dly. Doses may be given at
    any time of day without regard to
    meals. Lipid levels should be analyzed
    within 2-4 wks and dose adjust.
    accord. See lit.
    F.C. TABS: 30 x 40 mg, 80 mg.
    Initial: 10 mg 1 x dly. Incr. grad. to max.
    80 mg 1 x dly without regard to meals.
    Adjunct. to diet for tmt. elevated total
    and LDL cholesterol, apo B, triglyc. in pts.
    with prim. hypercholesterolem.,
    incl.
    famil. hypercholesterolem. (heterozyg.)
    or combined (mixed) hyperlipidemia
    (types IIa, IIb Fredrickson classific.) when
    response to diet and other non-pharm.
    measures alone has been inad. To reduce
    total-C and LDL-C in pts. with homozyg.
    famil. hypercholesterolem. as adjunct to
    other tmts. Ped: 10-17 yrs: Adjunct to diet
    to reduce total-C, LDL-C, apo B levels in
    boys and postmenarchal girls with
    heterozyg. famil. hypercholesterem. aft.
    an adequate trial of diet ther. with foll.
    findings: LDL-C remains ≥ 190 mg/dL or
    LDL-C remains ≥ 160 mg/dL with
    positive fam. history of prem. CV dis. or 2
    or more other CVD risk factors present.
    Prevent CV and/or cerebrovasc. events
    such as MI or stroke. Adjunct to correct
    other risk factors such as hypertens. (in
    pts with 3 or more additional risk factors
    or diabetes with one additional risk
    factor.)
    C/I: Hypersens., active liver dis.,
    unexplained elevat. serum
    transaminase, myopathy, pregn., lact.
    See lit.

    Litorva 10, 20, 40, 80 mg
    Dexcel
    RX
    partial basket chart
    Litorva 10, 20, 40, 80 mg

    Statin. Atorvastatin (as Calcium) 10, 20, 40, 80 mg.
    TABS: 30 X 10 mg, 20 mg, 40 mg, 80 mg.
    Usual Init dose: 10 or 20mg 1 × dly.
    Adjust. Dose at intervals of 4 wks or
    more. Max. dose for adults: 80mg 1xdly.
    Max. dose for children: 20 mg 1Xdly.
    Doses may be given at any time of day
    without regard to meals. Lipid levels
    should be analyzed within 2-4 wks and
    dose adjust. accord. See lit.
    Adjunct. to diet for tmt. elevated total
    and LDL-cholesterol, apo B triglyc. and
    to incr. HDL cholesterol in pts. with
    prim. hypercholesterolem., incl. famil.
    hypercholesterolem. (heterozyg.) or
    combined (mixed) hyperlipidemia
    (types IIa, IIb fredrickson classific.) when
    response to diet and other non-pharm.
    measures alone has been inad. To
    reduce total-C and LDL-C in patients
    with homozyg. famil.
    hypercholesterolem. as adjunct to other
    lipid-lower. tmt. (e.g. LDL apheres.) or if
    such tmts. unavail. Ped: 10-17 yrs:
    Adjunct to diet to reduce total-C, LDL-C,
    apo B levels in boys and postmenarchal
    girls (10-17 yrs of age) with heterozyg.
    famil. hypercholesterolem. aft. an
    adequate trial of diet ther. with foll.
    findings: LDL-C remains > or = 190 mg/
    dl, LDL-C remains > or = 160 mg/dl with
    positive fam. history of prem. CV dis. or
    two or more other CVD risk factors
    present in the pediatric patient. Prevent.
    CV and/or cerebrovasc. events such as
    MI or stroke. Adjunct to correct other
    risk factors such as hypertens. (in pts. with 3 or more additional risk factors or
    diabetes with one additional risk factor).
    Pts. with clinic. evident coronary heart
    dis: Reduce risk of non fatal MI. Reduce
    risk of fatal/non fatal stroke. Reduce risk
    of revasc. proced. Reduce risk of
    hospitalizat. for CHF. Reduce risk of
    angina. See lit.
    C/I: Hypersens. to Atorvastatin or
    ingreds or to similar blood lipid
    lowering. Pregn., Lact. and in woman of
    childbear. age not using adeq.
    contracept. Active or history of liver dis.,
    unexplained presistent elevat. serum
    transaminase exceeding 3 times the
    upper limit of normal. Myopathy. Ped.
    under 10 yrs/ premenstruation girls.
    Patients that take Cyclosporine,
    Telaprevir or a combination of
    Tipranavir and Ritronavir. See lit.

    Pravalip
    Unipharm
    RX
    full basket chart
    Pravalip

    Statin. Pravastatin Sodium 10, 20, 40 mg.
    TABS: 30 x 10 mg, 20 mg,
    40 mg. 10-40 mg dly at bedt.
    Response within 1-2 wks. Max. effect.
    4 wks. Elderly: Initiate at lower dose
    and monitor.
    Prim. prevent. coron. events: In
    hypercholest. pts. to reduce risks of M.I.
    revascularizat. and deaths due to CV
    causes with no incr. in deaths from non-CV
    causes. Second. prevent. CV events: In
    hypercholesterolem. pts. incl. prior M.I. to
    slow the progress. of coron. atheroscleros.
    and reduce the risk of acute coron. events.
    In pts. with prev. M.I. to reduce the risk of
    recur. M.I., risk of myocard. revasc. proced.,
    reduce the risk of stroke or transient
    ischem. attacks. In hypercholesterolem.
    and mixed dyslipidem. (Frederickson types
    lla and llb): As adjunct to diet to reduce
    elevat. total cholesterol, LDL - cholesterol
    and triglyceride levels.

    Pravastatin Teva
    Teva
    RX
    full basket chart
    Pravastatin Teva

    Statin. Pravastatin Sodium 10, 20, 40 mg.
    TAB: 30 x 10 mg, 20 mg,
    40 mg. Usual dosage range: 10-40
    mg dly at bedt. Dose response effect is
    apparent within 1-2 wks; Max. effect: 4
    wks. Perform periodic lipid determ. at
    intervals of not less than 4 wks. and
    adjust dosage. Not to be used under 18
    yrs of age. Elderly and pts. with hepat.
    or ren. impair: Initiate tmt. at the lower
    dosage range and monitor pts.
    Prim. prevent. coron. events: In
    hypercholest. pts. to reduce risks of M.I..
    revascularizat. and deaths due to CV causes
    with no incr. in deaths from non-CV causes.
    Second. prevent. CV events: In
    hypercholesterolem. pts. incl. prior M.I. to
    slow the progress. of coron. atheroscleros.
    and reduce the risk of acute coron. events.
    In pts. with prev. M.I. to reduce the risk of recur. M.I., risk of myocard. revasc. proced.,
    reduce the risk of stroke or transient ischem.
    attacks. In hypercholesterolem. and mixed
    dyslipidem. (Frederickson types lla and llb):
    As adjunct to diet to reduce elevat. total
    cholesterol, LDL - cholesterol and
    triglyceride levels.
    C/I: Known hypersens. to any ingred.,
    pregn., lact.; active liver dis. or
    unexplained, persistent elevat. in liver
    funct. tests.

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