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  • CNS Stimulants
    10 Drugs classified under this therapeutic system


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    Atomic 25, 40, 60
    Unipharm
    RX
    not in the basket chart
    Atomic 25, 40, 60

    Selective Norepinephrine Reuptake Inhibitor. Atomoxetine (as HCl) 25, 40, 60 mg.
    F.C. TABS.: 28×25, 40, 60mg. Paed. pts. up to 70 kg bdy. wt.: Initial. at a total dly dose of approx. 0.5 mg/kg. The initial dose should be maintain. for a min. of 7 d. prior to upward dose titrat. accord. to clinical response and tolerab. The recommended mainten. dose is approx. 1.2 mg/kg/d. (depend. on the pt’s. wt. and available dosage strengths of atomoxetine).
    Dosing of paed. pts. over 70 kg bdy. wt. and Adult.: The Drug should be initiated at a total daily dose of 40 mg. The initial dose should be maintain. for a min. of 7 d. prior to upward dose titrat. accord. to clinical response and tolerab.. The recomm. mainten. dose is 80mg. The max. recom. total dly. dose is 100 mg.
    Indicated for the tmt. of ADHD in child. of 6 yrs. and older, in adolesc. & in adult. as part of a comprehensive tmt. programme. Tmt.  must be initiated by a specialist in the tmt. of ADHD, such as a paediatrician, child/adolesc. psychiatrist, or psychiatrist. Diagnosis should be made accord. to current DSM criteria or the guidelines in ICD. In adult., the presence of sympt. of ADHD that were pre-exist. in childhood should be confirmed. Third-party corroboration is desirable and the drug  should not be initiated when the verification of childhood ADHD sympt. is uncertain. Diagnosis cannot be made solely on the presence of one or more sympt. of ADHD. Based on clinical judgment, pts. should have ADHD of at least moder. severity as indicated by at least moderate function. impair. in 2 or more settings (for example, social, academic, and/or occupational functioning), affecting several aspects of an individual’s life.
    C/I: Hypersens. Comb. with MAOI. Atomoxetine should not be used within a min. of 14 d. after discont. ther. with MAOI. Tmt. with MAOI should not be init. within 14 d. after discont. atomoxetine.
    Pts. with narrow-ang. glauc.
    Pts. with pheochromocytom.
    Pts. with severe card./vascular disord., hypertens., tachycard.

    Attent 5 mg, 10 mg, 20 mg, 30 mg
    Abic
    RX
    partial basket chart
    Multiple ingredients
    Attent 5 mg, 10 mg, 20 mg, 30 mg

    Amphetamines. Dextroamphetamine Saccharate 1.25, 2.5, 5, 7.5 mg, Amphetamine Aspartate Monohydrate 1.25, 2.5, 5, 7.5 mg, Dextroamphetamine Sulfate 1.25, 2.5, 5, 7.5 mg, Amphetamine Sulfate 1.25, 2.5, 5, 7.5 mg.
    TABS.: 100× 5, 10, 20, 30 mg. Not recom.
    for child. under 3 yrs. of age. Child. 6
    yrs. of age and older, start with 5 mg
    once/twice dly.; daily dosage may be
    inc. in increments of 5 mg at wkly.
    intervals until optim. response is
    obtained. Narcolepsy: Usual dose 5 mg
    - 60 mg per day in divided doses,
    depend. on the individ. pt. response. 
    Tmt. of ADHD and Narcolepsy.
    C/I: Hypertens., hyperthyroid., known
    hypersens./ idiosyncrasy to the
    sympathomim. amines. Glaucoma.
    Agitated states. Pts. with a hist.of drug
    abuse. During or within 14 days follow.
    the adminis. of MAO’s inhib. (hyperten.
    crises may result). Advanced
    arteriosclerosis, symptom. cardiovasc.
    dis., moder.- sev.

    Concerta
    Janssen
    RX
    full basket chart
    Concerta

    CNS Stimulant. Methylphenidate HCl 18, 27, 36, 54 mg.
    E.R. TABS: 30 x 18 mg, 27 mg, 36 mg, 54
    mg. Initial: 18 mg 1 x dly in the morn.
    May adjust in increments of 18 mg to
    max 54 mg dly, at approx. wkly
    intervals. Pts. new to methylphenidate
    or who are on other stimulants: 18 mg
    1 x dly. Pts. currently taking 5 mg
    methylphenidate 2 x dly or 3 x dly: 18
    mg. Pts. currently taking 10 mg 2 x dly
    or 3 x dly: 36 mg. Some cases: 54 mg.
    Max. dly dose: 54 mg.
    Tmt. attent. deficit hyperact. disord.
    (ADHD).

    Nuvigil 50, 150, 250 mg
    Abic
    RX
    partial basket chart
    Nuvigil 50, 150, 250 mg

    Psychostimulant. Armodafinil 50, 150, 250 mg.
    TABS.: 7, 28, 30, 60.
    Narcolepsy,  sleep disord. due to OSA: 150- 250 mg×1/d, in the morn. Sleep disord. due to working in shifts: 150 mg×1/d, about 1 hour before start.the shift.
    Armodafinil is indicat. to improve wakefulness in adult pts. with excessive sleepiness assoc. with obstruct. sleep apnea (OSA), narcolepsy, or shift work disorder (SWD).
    C/I: Hypersens. Hypersens. to Provigil or Modafinil.

    Provigil
    Abic
    RX
    partial basket chart
    Provigil

    Psychostimulant. Modafinil 100 mg.
    CAPLET.: 10, 30, 60, 90. init. reccomen.  dly. dose is 200 mg. The total dly. dose may be taken as a single dose in the morn. or as two doses, one in the morn. and one at noon. Doses of up to 400mg in one or two divid. doses can be used in pts. with insufficient response to the initial 200mg modafinil dose. See Lit.
    Improves wakefulness in pts. with excessive sleepiness assoc. with narcolepsy (with or without cataplexy), obstruct. sleep apnea/hypopnea syndr. (OSAHS) and shift work sleep disord. (SWDS).
    C/I: Hypersens. Uncontrol., moder.  to sev.  hypertens. and in pts. with card. arrhythm.


    Other therapeutic systems under Central Nervous System

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