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  • Neuropathic Pain Disorders
    13 Drugs classified under this therapeutic system


    All the Therapeutic System Drugs

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    Axiban Sublingual Drops IMC-Medical Grade Cannabis Oil
    Rafa
    RX
    not in the basket chart
    Multiple ingredients
    Axiban Sublingual Drops IMC-Medical Grade Cannabis Oil

    Cannabinoids. THC 0.3, 0.9, 1.5, 3, 4.5, 6 mg/drop, CBD 0.6, 0.9, 1.2, 3, 4.5, 6 mg/drop.
    *This product requires a license for medical cannabis.
    BOTTLE. (sublingual drop.): 10gr (330 drops). Dosage should be adjust. individual.
    The Israel MOH has outlined in Guidance 106 the 12 indicat. for which med. cannabis is indicated. Accord. to this guidance, the 11 indicat. for this product are:
    Chemother-induc. nausea and vomit. (CINV)/ chemother induc. pain.
    Metastat. cancer pain.
    IBD.
    Neuropath. pain.
    Spastic. of MS.
    Pain in Parkinson's dis.
    Cachexia in AIDS.
    Tourette's syndr.
    Recalcitrant epilep. in adult. (Note: Accord. to Guidance 106, med. cannab. is also indic. for recalcitrant epilep. in ped. pts. but this is not an indicat. for this product)
    Palliative care for termin. ill pts.
    Post- traum. stress disord.
    In general, the use of med. cannabis is indicated in pts. who have adequate. tried and failed convent. ther.
    Please refer to Guidance 106 for details.
    In addition, for an individ. pt. with a clinical. signific. med. condit. that cannot be adequate. managed by convent. ther. and which is not includ. as one of the 12 approved indicat. (eg autism, fibromyalgia), the physician can appeal to the MOH Committee for Med. Cannabis to ask for approval on an individ. exception. basis.
    C/I: Prior, current/ family history (1st degr. relative) of psychos. or schizophr. or schizoaffective disord., a hist. of addict. or substance abuse (include. cannabis use disord.or addict. to alcohol), use in preg.or lact., use in pts. <18 yrs. old, bipol.disord., hypersens. to cannabis, coconut oil, palm kernel oil.
    In pts. with hepat. cancer, it is recommend. not to use med. cannab. that contains THC.
    See lit.

    Cymbalta
    Eli Lilly
    RX
    partial basket chart
    Cymbalta

    SNRI. Duloxetine HCl 30 mg, 60 mg.
    CAPS: 7,14,28 x 30 mg, 60 mg.
    intial: 30 mg dly. maint: 60 mg dly.
    Ther. response: 2-4 wks aft. tmt. To
    discont: Taper by 1/2 dose (30 mg) dly
    or on alt. days. See lit.
    Major depress. episodes., Generalized
    anxiety dis., Neuropath. pain assoc.
    with diabet. periph. neuropathy.,
    fibromyalg., chron. muscoskeletal pain.
    C/I: Concom. use with MAOI,
    uncontrolled narrow-angle glaucoma.

    Dulox Teva 30 & 60 mg
    Abic
    RX
    partial basket chart
    Dulox Teva 30 & 60 mg

    SNRI. Duloxetine 30 , 60 mg.
    CAPS.:30. For diabet. peripher. neuropath.  pain: The usual dose is 60 mg ×1/d.
    For chron. musculoskel. pain and general. anxiety disord.: For most pts.
    60 mg ×1/d. Some pts. require an init. dose of Dulox Teva 30 mg ×1/d for one wk., and then the usual dose of
    60 mg ×1/d.
    For depression: Most pts. will receive 60 mg ×1/d. Some pts. require an init. dose of Dulox Teva 30 mg ×1/d for one wk., and then the usual dose of 60 mg ×1/d
    Elderly – The init. dose of 30 mg ×1/d for two wks., and only then consider incr. the dose to 60 mg ×1/d.
    Fibromyalgia: The init. dose of Dulox Teva is 30 mg ×1/d  for one wk., and then the usual dose of 60 mg ×1/d. In most cases, the effect of medication ther. with Dulox Teva is noticeab. after 2-4 wks. of tmt.
    See lit.
    Tmt. of major depressive episodes.
    Managem. of neuropath.pain associat. with diabet. peripher. neuropathy.
    Tmt. of generaliz. anxiety disord. (GAD).
    Manag. of fibromyalgia.
    Manag. of chron. muscoskel. pain when other therapies have failed or are
    contraindic. This has been establish. in studies in pts. with chron. low back pain (CLBP) and chron. pain due to osteoarthritis.
    C/I: Hypersens.
    Pts. with hep. dis.
    Pts.  with severe ren. dis..
    Concom. use with MAOI  includ. IV methylene blue and the antibiot.linezolid. MAOI should be discount. 14 d. before init.of the tmt. with duloxetine.
    Initiat. of MAOI should be start. at least 5 d. after discount. of the tmt. with duloxetine.
    Concom. use with thioridazine

    Duloxetine DR Teva
    Teva
    RX
    partial basket chart
    Duloxetine DR Teva

    SNRI. Duloxetine (as HCl) 20, 30, 60 mg.
    DR CAPS: 30 ×20mg, 30mg, 60mg.
    Major depres.disor. 60 mg/d.
    GAD: init. reccom. dose 30 mg ×1/d for
    1 week, may be incr. to 60 mg ×1/d.
    Max until: 120mg x 1/d.
    Diab. periph. neurop. pain: 60 mg x
    1/d; lower init., dose, grad. incr. in pts.
    with ren. impair.
    Fibromyal.: init. 30 mg x 1/d; for 1
    week, may be incr. to 60 mg ×1/d.
    Chron. musculoskel. pain: init. 30 mg
    start at 30 mg ×1/d for 1 week, may be
    incr. to 60 mg ×1/d.
    Tmt. of Major. depress. epis.; manag. of
    neurop. pain assoc. with diab. periph.
    neurop. Tmt. of GAD; Fibromyal.; Manag.
    of chron. muscoskel. pain when other ther.
    have fail.or are contra-ind.
    C/I: Hypersens. , Liver dis. result. in hep.
    impair., Sev. ren. impair., Pts. und. other
    medic. contain. duloxetine.
    Concom. use with MAOIs or within 14 d.
    after use MAOIs Init. of tmt. with MAOIs
    should be start. only on a 5th day elapse
    from stop. tmt. with Duloxetine.
    Concom. use with fluvoxamine,
    thioridazine, cimetidine, quinolone.
    Concom. use with ciprofloxacin or
    enoxacin Pts. with uncontr. narr.-ang.
    glauc.

    Gabapentin Inovamed 300 mg, 400 mg
    Inovamed
    RX
    partial basket chart
    Gabapentin Inovamed 300 mg, 400 mg

    GABA Analog. Gabapentin 300 mg, 400 mg.
    CAPS: 100 x 300 mg, 400 mg. With/out
    food with full glass water. Titrate over a
    few days to max. dose of 1,800 mg dly
    in 3 div. doses. Discont. grad. over min.
    of 1 wk. See lit.
    Adjunct. tmt. partial seizures with/out
    second. generalizat. in adults with epilepsy. Tmt. neuropath. pain in diabet.
    neuropathy, post-herpetic neuropathy
    (neuralgia).
    C/I: Hypersens. See lit.

    Gabapentin Teva
    Teva
    RX
    partial basket chart
    Gabapentin Teva

    GABA Analog. Gabapentin 300, 400,.
    CAPS: 100 x 300 mg, 400 mg. Titrate. to max. 900-1,800 mg dly in 3 div. doses with/without food. To minimize S/E. Day 1: 300 mg at bedt. Day 2: 300 mg 2 xdly; Day 3: 300 mg 3 x dly, not more than 12 hrs apart. Can incr. by 300 mg/ dly in 3 div. doses to max. 1800 mg/ day. To discont.,decr. orsubstit: Grad. over min. 1 wk. Elderly: Adjust as reqd. See lit.
    As adjunct.ther. in the tmt. of part. seizures
    with and without second. generaliz. in adults
    with epilepsy. – Tmt. of neuropath. pain in
    diab. neuropat. orpostherpeticneuropat.(neuralgia).
    C/I: Hypersens.


    Other therapeutic systems under Central Nervous System

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