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  • SNRI
    9 Drugs classified under this drug class

    All the Drug Class Drugs

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    Eli Lilly
    partial basket chart

    SNRI. Duloxetine HCl 30 mg, 60 mg.
    CAPS: 7,14,28 x 30 mg, 60 mg.
    intial: 30 mg dly. maint: 60 mg dly.
    Ther. response: 2-4 wks aft. tmt. To
    discont: Taper by 1/2 dose (30 mg) dly
    or on alt. days. See lit.
    Major depress. episodes., Generalized
    anxiety dis., Neuropath. pain assoc.
    with diabet. periph. neuropathy.,
    fibromyalg., chron. muscoskeletal pain.
    C/I: Concom. use with MAOI,
    uncontrolled narrow-angle glaucoma.

    Duloxetine DR Teva
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    Duloxetine DR Teva

    SNRI. Duloxetine (as HCl) 20, 30, 60 mg.
    DR CAPS: 30 ×20mg, 30mg, 60mg.
    Major depres.disor. 60 mg/d.
    GAD: init. reccom. dose 30 mg ×1/d for
    1 week, may be incr. to 60 mg ×1/d.
    Max until: 120mg x 1/d.
    Diab. periph. neurop. pain: 60 mg x
    1/d; lower init., dose, grad. incr. in pts.
    with ren. impair.
    Fibromyal.: init. 30 mg x 1/d; for 1
    week, may be incr. to 60 mg ×1/d.
    Chron. musculoskel. pain: init. 30 mg
    start at 30 mg ×1/d for 1 week, may be
    incr. to 60 mg ×1/d.
    Tmt. of Major. depress. epis.; manag. of
    neurop. pain assoc. with diab. periph.
    neurop. Tmt. of GAD; Fibromyal.; Manag.
    of chron. muscoskel. pain when other ther.
    have fail.or are contra-ind.
    C/I: Hypersens. , Liver dis. result. in hep.
    impair., Sev. ren. impair., Pts. und. other
    medic. contain. duloxetine.
    Concom. use with MAOIs or within 14 d.
    after use MAOIs Init. of tmt. with MAOIs
    should be start. only on a 5th day elapse
    from stop. tmt. with Duloxetine.
    Concom. use with fluvoxamine,
    thioridazine, cimetidine, quinolone.
    Concom. use with ciprofloxacin or
    enoxacin Pts. with uncontr. narr.-ang.

    Efexor XR
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    Efexor XR

    SNRI. Venlafaxine (HCl) 75 mg, 150 mg.
    E.R. CAPS: 28. 1 cap dly.
    C/I: Hypersens., pregn., lact., under 18
    yrs., concur. with MAOI’s (at least 7 days
    betw. end of tmt. with Efexor and start
    of MAOI’s). See lit.

    partial basket chart

    SNRI. Milnacipran (HCl) 25 mg, 50 mg.
    CAPS: 14,28,56,112. 100 mg in 2 div.
    Tmt. of major depress. epis. in adult.over
    18 yrs. old.
    C/I: Hypersens. Concom. use with nonselec.
    MAOIs , B selec. MAOIs, digitalis , 5
    HT1D agon. Sev. card. impair.,
    arrhythmia (e.g. sign. left ventr. dysfunc.,
    NYHA Class III/IV), uncontr. hypertens.,
    sev., unst. coron. heart dis., lact. General.
    shouldn’t be use concom. with
    epinephrine, norepinephrine by parent.
    route, clonidine , related comp. and A
    selec. MAOIs.Prost.hypertrop., other gen.
    urin. disor. Preg.

    partial basket chart

    SNRI. Venlafaxine (as HCl) 37.5 mg, 75 mg.
    TABS: 28. 2 tabs dly.
    C/I: Hypersens., pregn., lact., concur. use
    MAOI’s. See lit.

    Venlafaxine XR Teva
    partial basket chart
    Venlafaxine XR Teva

    SNRI. Venlafaxine (HCl) 75, 150 mg.
    E.R. TABS: 30. Initial: 75 mg dly in single
    dose; for non-responders: Incr. up to
    225 mg dly in dly increments of up to
    75 mg at intervals of not less than 4
    days. Re-ass. regular. to evaluat.
    benefit of long term ther. Hepat.
    impair: Reduce init. dose by 50%. Ren.
    impair: Reduce total dly dose by
    25-50%. Pts. on hemodialys: Reduce by
    50%, withhold until dialys. tmt
    complet. (4 hrs). Elderly: No dos. adjust. needed. Care when incr. dose. Maint./
    extend. tmt: Perform period. evaluat.
    Discont: Taper grad., monitor pt.
    Switch. to/from MAOI: Allow at least 14
    days between discont. MAOI and
    initiat. of ther. Allow at least 7 days of
    discont. ther. bef. start tmt. with MAOI.
    Tmt. depress., maint. recurr. depress,
    GAD, short/long term SAD.
    C/I: Known hypersens., concom. use
    with MAOIs.