Anticonvulsant

27 Drugs classified under this drug class

Anticonvulsant. Sodium Valproate 200 mg, 500 mg.
E.C. TABS: 40 x 200 mg, 500 mg.
SOLN: 50 ml x 200 mg/ml.
SYR: 110 ml x 200 mg/5 ml. Initial:
10-15 mg/kg bdy. wt. dly. incr. at 5
days or 1 wk. intervals by 5 mg/kg bdy.
wt. dly. Elderly: 15 mg/kg dly. Adults:
20 mg/kg dly. Child. and Inf: 25 mg/kg
dly. To be assessed aft. 2-3 wks. ther.
See lit.
All forms of epilepsy (grand, petit, mixed
or partial), porphyria.

Anticonvulsant. Phenytoin Sodium 125 mg/5 ml.
SUSP: 8 oz. 1 teasp. 3 x dly. (to be
adjust. to individ. req.).
Grand mal, psychomotor seizures.

Anticonvulsant. Phenytoin Sodium 100 mg.
CAPS: 100. 100 mg 2-4 x dly bef. meals.
Max dly dose: 600 mg.
Grand mal, psychomotor seizures.
C/I: Hypersens. to hydantoin.

Anticonvulsant. Rufinamide 100, 200, 400 mg.
F.C. TABS: 10 x 100 mg, 60 x 200 mg, 400
mg. See lit.
Adjunct. ther. tmt. seizures assoc. with
Lennox-Gastaut syndr. in pts. > 4 yrs.
C/I: Hypersens.

Anticonvulsant. Levetiracetam 250, 500, 1000 mg.
F.C. TABS: 60 x 250 mg, 500 mg, 1,000
mg. Adult,
child & adolesc. 12-17 yrs, wt. 50 kg or
more: Initial: 500 mg 2 x dly on 1st day
of tmt. Depend. on clin. response/
tolerabil. can incr. dly dose up to 1,500
mg 2 x dly. Dose changes can be made
in 500 mg increments/decrements 2 x
dly every 2-4 wks. Child 4-17 yrs wt.
less than 50 kg: Initial 10 mg/kg body
wt 2 x dly. Depend. on clin./tolerabil,.
incr. up to 30 mg/kg bdy wt. 2 x dly
every 2 wks. Dose changes not to
exceed increments/decrements of 10
mg/kg bdy wt. 2 x dly every 2 wks. Use
lowest effect. dose. Inf./child under 4
yrs: Not recommend. Elderly: Adjust if
renal funct. compromised. Renal
impair: Adjust individ. accord. to ren.
funct. Severe hepat. impair: Creatinine
clear. may underest. ren. insuffic; 50%
reduct. dly maint. dose is recommend.
at creatinine clear. of <70 ml/min.
Adjunct. ther. tmt partial onset seiz. with/
without second. generaliz. pts with
epilepsy.
C/I: Hypersens.

Anticonvulsant. Levetiracetam 100 mg/ml.
ORAL SOLN: 300 ml x 100 mg/ml. Adult,
child & adolesc. 12-17 yrs, wt. 50 kg or
more: Initial: 500 mg 2 x dly on 1st day
of tmt. Depend. on clin. response/
tolerabil. can incr. dly dose up to 1,500
mg 2 x dly. Dose changes can be made
in 500 mg increments/decrements 2 x
dly every 2-4 wks. Child 4-17 yrs wt.
less than 50 kg: Initial 10 mg/kg body
wt 2 x dly. Depend. on clin./tolerabil,.
incr. up to 30 mg/kg bdy wt. 2 x dly
every 2 wks. Dose changes not to
exceed increments/decrements of 10
mg/kg bdy wt. 2 x dly every 2 wks. Use
lowest effect. dose. Inf./child under 4
yrs: Not recommend. Elderly: Adjust if
renal funct. compromised. Renal
impair: Adjust individ. accord. to ren.
funct. Severe hepat. impair: Creatinine
clear. may underest. ren. insuffic; 50%
reduct. dly maint. dose is recommend.
at creatinine clear. of <70 ml/min.
Adjunct. ther. tmt partial onset seiz. with/
without second. generaliz. pts with
epilepsy.
C/I: Hypersens.