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  • Anticonvulsant
    28 Drugs classified under this drug class


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    Depalept
    CTS
    RX
    full basket chart
    Depalept

    Anticonvulsant. Sodium Valproate 200 mg, 500 mg.
    E.C. TABS: 40 x 200 mg, 500 mg.
    SOLN: 50 ml x 200 mg/ml.
    SYR: 110 ml x 200 mg/5 ml. Initial:
    10-15 mg/kg bdy. wt. dly. incr. at 5
    days or 1 wk. intervals by 5 mg/kg bdy.
    wt. dly. Elderly: 15 mg/kg dly. Adults:
    20 mg/kg dly. Child. and Inf: 25 mg/kg
    dly. To be assessed aft. 2-3 wks. ther.
    See lit.
    All forms of epilepsy (grand, petit, mixed
    or partial), porphyria.

    Depalept Chrono
    Sanofi
    RX
    full basket chart
    Multiple ingredients
    Depalept Chrono

    Anti-Epileptic, Anticonvulsant. Sodium Valproate 333 mg, Valproic Acid 145 mg.
    P.R. TABS: 30. The Init. dly. dosage is usually 10-15 mg/kg, after which doses are incr. up to the optim. dose.
    The mean dosage is 20-30 mg/kg/d. However, if seizures are not brought under control at this dosage it may be incr. and pts. must be closely monitor.
    In child., usually 30 mg/kg/d.
    In adults, usually 20 to 30 mg/kg/d.
    In elderly pts., the dosage should be determ. based on the control of seizur. Tmt. and preven. of manic episodes in the context of bipolar disord.: The recomm. init. dose is 1000 mg/d. The dose should be incr. as fast as possible to the low. dose that brings about the desired clinic. effect. The recomm. mainten. dose for the tmt. of bipolar disord. is between 1000 mg & 2000 mg dly. In except. cases the dose may be incr. to a max. of 3000 mg dly. Dosage should be adjust. individ. See lit.
    Epilepsy: Tmt. of general./partial epilep. second. epilep. and mixed forms of epilep.
    Bipolar disord.: Tmt. and/or prevent. of acute manic episodes in the context of bipolar disord.
    C/I: History of hypersens. to valproate, divalproate, valpromide. Acute hepatit. Chron. hepatit. Hep. porphyria. Person./famil. history of sev. hepatit., in particular drug-related.
    Comb. use with mefloquine and St.-John`s-wort. Pts. known to have mitochond. disord. caused by mutations in the nuclear gene encod. mitochond. enzyme polymerase γ (POLG, e.g. Alpers-Huttenlocher Syndr.). Pts. with known urea cycle disord.

    Dilantin 125
    Pfizer
    RX
    full basket chart
    Dilantin 125

    Anticonvulsant. Phenytoin Sodium 125 mg/5 ml.
    SUSP: 8 oz. 1 teasp. 3 x dly. (to be
    adjust. to individ. req.).
    Grand mal, psychomotor seizures.

    Epanutin
    Pfizer
    RX
    full basket chart
    Epanutin

    Anticonvulsant. Phenytoin Sodium 100 mg.
    CAPS: 100. 100 mg 2-4 x dly bef. meals.
    Max dly dose: 600 mg.
    Grand mal, psychomotor seizures.
    C/I: Hypersens. to hydantoin.

    Inovelon
    Megapharm
    RX
    partial basket chart
    Inovelon

    Anticonvulsant. Rufinamide 100, 200, 400 mg.
    F.C. TABS: 10 x 100 mg, 60 x 200 mg, 400
    mg. See lit.
    Adjunct. ther. tmt. seizures assoc. with
    Lennox-Gastaut syndr. in pts. > 4 yrs.
    C/I: Hypersens.

    Keppra
    CTS
    RX
    partial basket chart
    Keppra

    Anticonvulsant. Levetiracetam 250, 500, 1000 mg.
    F.C. TABS: 60 x 250 mg, 500 mg, 1,000
    mg. Adult,
    child & adolesc. 12-17 yrs, wt. 50 kg or
    more: Initial: 500 mg 2 x dly on 1st day
    of tmt. Depend. on clin. response/
    tolerabil. can incr. dly dose up to 1,500
    mg 2 x dly. Dose changes can be made
    in 500 mg increments/decrements 2 x
    dly every 2-4 wks. Child 4-17 yrs wt.
    less than 50 kg: Initial 10 mg/kg body
    wt 2 x dly. Depend. on clin./tolerabil,.
    incr. up to 30 mg/kg bdy wt. 2 x dly
    every 2 wks. Dose changes not to
    exceed increments/decrements of 10
    mg/kg bdy wt. 2 x dly every 2 wks. Use
    lowest effect. dose. Inf./child under 4
    yrs: Not recommend. Elderly: Adjust if
    renal funct. compromised. Renal
    impair: Adjust individ. accord. to ren.
    funct. Severe hepat. impair: Creatinine
    clear. may underest. ren. insuffic; 50%
    reduct. dly maint. dose is recommend.
    at creatinine clear. of <70 ml/min.
    Adjunct. ther. tmt partial onset seiz. with/
    without second. generaliz. pts with
    epilepsy.
    C/I: Hypersens.

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