All the biological system drugs
Anticholinergic agent. Atropine Sulphate 1 mg/ml. AMP. (sol. for IM, IV inj.): 5×1ml. Pre-anesthet. med.: Adults: 0.3-0.6 mg by IV inj. immed. before the anesthes. induct. or by IM inj. 30-60 min. before the induc.
Child.: 0.02 mg/kg (max. dose 0.6 mg).
Tmt. of sinus bradycard.: 0.3 and 1.0 mg IV.
Antidote in poison. by organophosphorus:
Adult.: 2 mg (IM or IV, taking into account the sever. of the poison.) every 5-10 min., until the skin becomes red and dry, the pupils dilate and tachycard. appears.
Child.: The 0.02 mg/kg.
Preanesthetic medication to decrease excessive salivation and secretions of the respiratory tract. Treatment of sinus bradycardia, particularly if complicated by hypotension.
Antidote in poisoning by organophosphorus.
C/I: Hypersens. Clos. ang. glauc., esophag. reflux, pyloric stenosis, GI obstruct., ulcerat. colit., prostat. hypertrophy, paralytic ileus, intest. atony.
Alkylating Agent. Calcium Folinate 10 mg/ml. VIALS (sol. for inj.): 1 x 100 mg/10 ml, 200 mg/20 ml, 500 mg/50 ml, 1000 mg/100 ml.
I.V./I.M. only. If use I.V: No more than
160 mg/min, diluted with 0.9% sod.
chlor. sol. or 5% glucose sol. See lit.
To diminish the toxic. and counteract the
action of folic acid antagonists in
cytotoxic ther. As Leucovorin-Fluorouracil
chemotherapy comb. for cancer tmt.
C/I: Hypersens., pernicious anem., other
anem. due to B12 defic.
Iron Chelating Agent. Deferasirox 125mg, 250 mg, 500 mg. Dispers. tabs. X 28.Transfusional iron overload: recomm. initial daily dose is 20 mg/kg body weight.
Non-transfusion-dependent thalassemia syndromes: recomm. initial daily dose is 10 mg/kg body weight.
Chron. iron overload caused by blood transfus. (transfusional haemosiderosis) in ault and paed pts. (aged 2 years and over).
Chron. iron overload in pts with non-transfus.-depend. thalassaemia syndr. aged 10 years and older.
Chelat. ther. should only be init. when evident iron overload (liver iron concentr. [LIC] ≥5 mg Fe/g dry weight [dw] or serum ferritin consist. >800 μg/l). LIC is the preferred method of iron overload determin.
C/I: Hypersens. to the act. sub. or any excip. Combin. with other iron chelator therap. Pts with estim.creatinine clear. <60 ml/min. See lit.
Chelating Agent. Deferoxamine Mesylate 0.5 g. VIALS: 10 x 500 mg. I.M. inject., I.V./S.C.
infus: 20-60 mg dly. See lit.
Chronic iron overload; acute iron
poisoning; diagn. test for iron overload,
chron. alumin. overload in renal fail. in
maint. dialysis, aluminum-related bone
dis., dialysis enceph., anem. Diagnosis iron
overload.
C/I: Hypersens., pregn., lact.
Sympathomimetic. Epinephrine 0.3 mg /0.3 ml. AUTO-INJECTOR: (for intramusc. use for
immediate self-admin.) Single units.
Delivers a single dose of 0.3 mg for
adults and child over 30 kg.
Severe allerg. react. (anaphylaxis) to
hymenoptera stings, foods and other
allergens and in life threatening
situations
caused by asth. attack.
C/I: See lit. (In life-threat. sit. no
absolute C.I.).
Sympathomimetic. Epinephrine 0.15 mg / 0.3 ml. AUTO-INJECTOR: (for intramusc. use for
self-admin.) Single unit. Delivers a
single dose of 0.15 mg as support. ther.
Child (over 15 kg): 0.01 mg/kg bdy. wt.
Severe allerg. react. (anaphylaxis) to
hymenoptera stings, foods and other
allergens and in life threat. situations
caused by asth. attack.
C/I: See lit. (In life-threat. sit. no absolute
C.I.).
