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  • Alkylating Agent
    11 Drugs classified under this drug class


    All the Drug Class Drugs

    Filter by letter: ALL A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
    Alkeran
    Perrigo
    RX
    not in the basket chart
    Alkeran

    Alkylating Agent. Melphalan 2 mg, 50 mg/vial.
    fetotal of 150-200 mg. Child: Not more
    than 0.06 mg/kg bdy. wt. dly.
    Multiple myeloma, seminoma of testes
    and other malign. conds.
    AMPS: 1.8 ml of acid alcohol solv., 9 ml
    of diluent x 100 mg. (Hosp. only). I.V: 1
    mg/kg bdy. wt. repeat. in 8 wks.
    accord. to response.
    Reg. perfus. for malign. melanoma and
    other malign.
    C/I: Neutrophil count of less than 1,500/
    ml, concurrent radio or chemotherapy,
    low platelet count.

    Busulfex
    Tzamal
    RX
    partial basket chart
    Busulfex

    Alkylating Agent. Busulfan 60 mg / 10 ml.
    VIALS (sol. for inject.): 1. Every 6 hrs. for
    4 consec. days for total of 16 doses.
    In comb. with other chemother. agents
    and/or radiother. as cond. ther. prior to
    hematopoietic progenitor cell transplant.
    C/I: Hypersens.

    Calciumfolinat “Ebewe” 10 mg/ml
    Novartis
    RX
    not in the basket chart
    Calciumfolinat “Ebewe” 10 mg/ml

    Alkylating Agent. Calcium Folinate 10 mg/ml.
    VIALS (sol. for inj.): 1 x 100 mg/10 ml, 200 mg/20 ml, 500 mg/50 ml, 1000 mg/100 ml.
    I.V./I.M. only. If use I.V: No more than
    160 mg/min, diluted with 0.9% sod.
    chlor. sol. or 5% glucose sol. See lit.
    To diminish the toxic. and counteract the
    action of folic acid antagonists in
    cytotoxic ther. As Leucovorin-Fluorouracil
    chemotherapy comb. for cancer tmt.
    C/I: Hypersens., pernicious anem., other
    anem. due to B12 defic.

    Dacarbazine Medac
    Tzamal
    RX
    partial basket chart
    Dacarbazine Medac

    Alkylating Agent. Dacarbazine (as Citrate) 200, 500, 1000 mg/vial.
    SINGLE DOSE VIALS (Pwdr. for sol. for
    inject./infus.): 1, 10 x 200 mg; (Pwdr. for
    soln for infus.): 1, 10 x 500 mg, 1,000 mg.
    Malign. melanoma: (as single agent):
    200-250 mg/m2 bdy surface area/day)
    I.V. for 5 days every 3 wks. Alt: Shortterm
    infus. (over 15-30 mins). Also
    possible: I.V. 850 mg/m2 on day 1, then
    once every 3 wks. Hodgkin’s dis: 375
    mg/m2 I.V. every 15 days in comb. with
    doxorubicin, bleomycin and
    vinblastine. See lit.
    Malign. melanoma, Hodgkin’s dis.
    C/I: Hypersens., pregn., lact., leucopen.,
    and/or thrombocytopen., severe liver/
    kidney dis.

    Dacarbazine-Dacin
    Pharmalogic
    RX
    partial basket chart
    Dacarbazine-Dacin

    Alkylating Agent. Dacarbazine 200 mg/vial.
    VIALS (pwdr. for reconstit.): 1 x 200 mg +
    19.7 ml water. I.V. inject.,/infus.
    Monother: 4-5 day cycles of 150-250
    mg/m² bdy surface/day. May repeat
    every 21 days. Alt. tmt: 2.0-4.5 mg/kg/
    day for 1-10 days. Can repeat every 28 days. Inject over ±1 min/infus. over
    15-30 mins. If necess. may be given I.A.
    Comb. chemother: 4-5 day cycles of
    100 mg/m²/day with 21 day intervals
    start. from last day tmt.
    Metastat. malign. melanoma, Hodgkin’s
    dis. as 2nd line ther. when used in comb.
    with other agents.
    C/I: Hypersens., ren. insuffic., bone
    marrow defic., pregn., lact.

    Endoxan
    Megapharm
    RX
    partial basket chart
    Endoxan

    Alkylating Agent. Cyclophosphamide 500 mg, 1 g.
    VIALS (pwdr. for reconst.): 1 x 25 ml (500 mg), 50 ml (1g). See lit.
    Malign. lymphoma, Hodgkin’s dis.,
    lymphocyt. lymphoma, mixed cell type
    lymphoma, Burkitt’s lymphoma, multiple
    myeloma, leukem., mycos. fungoides,
    neuroblastoma, ovary adenocarcinoma,
    retinoblastoma, breast carcinoma, SLE.
    C/I: Hypersens., impair. bone marrow
    funct., pregn., lact.

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