Male Sexual Disorders

19 Drugs classified under this therapeutic system

Androgen. Testosterone 0.05 g/dose.
GEL (in unit-dose sachet): 30 x 5 g.
Adults and elderly: Apply 5 g (50 mg
testosterone) 1 x dly, at same time ea.
day, prefer. morn. Adjust accord.
individ. req. Not more than 10 g dly.
Testosterone replace. ther. for male
hypogonad. when testosterone defic.
confirmed.

Androgen. Testosterone Undecanoate 40 mg.
CAPS: 30. Initial: Usually 120-160 mg
for 2-3 wks. Subsequent dosage:
40-120 mg dly. (depend. on clinical
effect obtained in first wks. of ther.),
and accord. to severity of sympt. and
individ. response.
Replacement ther. in male hypogonad.
disords.

Prostaglandin. Alprostadil 10 mcg, 20 mcg.
VIAL: 1 x 10 μg, 20 μg sterile pwd. + 1 ml
diluent (in a prefilled syringe). Direct
intracavernosal inject. See lit.
Erectile dysfunct., adjunct. to diagn.
erectile dysfunct.
C/I: Hypersens., pts. with predispos. to
priapism.

Phosphodiesterase-5 Enzyme Inhibitor. Tadalafil 2.5, 5, 10, 20 mg.
F.C. TABS: 4 x 10 mg; 4, 8 x 20
mg. On-demand: 10 mg or 20 mg,
depend. response, 30 mins. - 12 hrs
bef. Sexual activity. Effic. may persist
for up to 36 hrs. Max: 1 dose dly, but
dly use not recommend. Child: Under
18 yrs: Not recommend.
F.C. TABS: 28 x 2.5 mg, 5 mg. Onceaday:
For men who anticipate freq. use
(min. 2 x wkly): 2.5 mg/5 mg 1 x dly,
depend. on individ. tolerabil. Reassess period. See lit.
Treatment of erectile dysfunction
(ED) in adult men. Also indicated for the
treatment of the signs and symptoms of
benign prostatic hyperplasia (BPH), also
indicated for the treatment of ED and the
signs and symptoms of BPH (ED/BPH).
CIALIS is not indicated for use by women.
C/I: Co-adminis. nitrates. Card.dis. I,Uns.
ang. uncont. Arrhythmias,
hypotens. Uncontr. Hypertens. Use by
women, see lit.

Phosphodiesterase-5 Enzyme Inhibitor. Vardenafil (as HCl) 5 mg, 10 mg, 20 mg.
TABS: 2, 4 x 5 mg, 10 mg; 8 x 20 mg.
Recommend. start. dose: 10 mg 25-60 mins. bef. intercourse. May incr. to 20 mg or decr. to 5 mg. Max: 20 mg/day.
Max: 1 x dly. Over 65 yrs: Initial: 5 mg.
Tmt. of erectile dysfunct. In order for the drug to be effective, sexual stimul. is required. Not indicated for use by women.
C/I: Hypersens. Co-admin. with nitrates, nitric oxide donors (e.g. as amyl nitrite). Pts. who have loss of vision in one eye because of non-arteritic anter. ischem. optic neuropathy (NAION), regardless of whether this episode was in connect. or not with prev. phosphodiesterase 5 (PDE5) inhib.
Meds. products for the tmt. of erectile dysfunct. should general. not be used in men for whom sex. activ. is inadvis. (e.g. pts. with sev. cardiovasc. disord. such as unstab. angina or sev. card. fail. [NYHA III or IV]).
Severe hep. impair. (Child-Pugh C), end stage ren. dis. requir. dialys., hypotens. (BP 90/50 mmHg), Recent hist. of stroke or MI (within the last 6 mnths.), unstab. ang. and known hered. retin. degenerate. disord. such as retinit. pigmentosa.
Concom. use with the potent CYP3A4 inhib. ketoconazole & itraconazole (oral form) is contraind. in men older than 75 yrs.
Concom. use with HIV protease inhib. such as ritonavir & indinavir. Co-admin. of PDE5 inhib., with guanylate cyclase stimulat., (e.g. riociguat).

Phosphodiesterase-5 Enzyme Inhibitor. Vardenafil 10 mg.
ORODISPERSIBLE TABS: 4. Recommend. dose: 1 orodisp. tab. 25-60 mins. bef. intercourse. Max: 1 x dly (with/out food).
Tmt. of erectile dysfunct. In order for the drug to be effective, sexual stimul. is required. Not indicated for use by women.
C/I: Hypersens. Co-admin. with nitrates, nitric oxide donors (e.g. as amyl nitrite). Pts. who have loss of vision in one eye because of non-arteritic anter. ischem. optic neuropathy (NAION), regardless of whether this episode was in connect. or not with prev. phosphodiesterase 5 (PDE5) inhib.
Meds. products for the tmt. of erectile dysfunct. should general. not be used in men for whom sex. activ. is inadvis. (e.g. pts. with sev. cardiovasc. disord. such as unstab. angina or sev. card. fail. [NYHA III or IV]).
Severe hep. impair. (Child-Pugh C), end stage ren. dis. requir. dialys., hypotens. (BP 90/50 mmHg), Recent hist. of stroke or MI (within the last 6 mnths.), unstab. ang. and known hered. retin. degenerate. disord. such as retinit. pigmentosa.
Concom. use with the potent CYP3A4 inhib. ketoconazole & itraconazole (oral form) is contraind. in men older than 75 yrs.
Concom. use with HIV protease inhib. such as ritonavir & indinavir.
Co-admin. of PDE5 inhib., with guanylate cyclase stimulat., (e.g. riociguat).