All the Therapeutic System Drugs
Vasopressin Analog. Desmopressin Acetate 0.1 mg, 0.2 mg. TABS: 30. Central diabetes. insipid:
Initial: Child and adult: 0.1 mg 3 x dly.
Adjust accord. to pt. response. Average
dly dose: 0.2 and 1.2 mg. For most pts,
opt. dose: 0.1-0.2 mg 3 x dly. Nocturn.
enures: Initial: 0.2 mg at bedt., may
incr. to 0.4 mg. Nocturia: 0.1 mg at
bedt. If no effect aft. 1 wk., incr. to 0.2
mg and then to 0.4 mg by wkly
increases. If adeq. medical effect not
achieved within 4 wks, discont.
Central diabetes insip., nocturn. enures.
(in pts from 5 yrs of age with normal abil.
to concentrate urine), symptomat. tmt
noct. in adults assoc. with noct. polyuria.
tmt. must be started bef. age of 65.
C/I: Habit. or psychogen. polydips., SIADH
syndr., known hyponatrem., known or
suspect. card. insuffic./other conds. req.
tmt. with diuretics, mod/severe ren.
insuffic. (creatinine clear. <50 ml/min),
Vasopressin Analog. Desmopressin Acetate 0.1 mg, 0.2 mg. SOLN: (Dropper bottle with plastic
catheter): 2.5 x 0.1 mg/ml. Cranial
diabet. insip: Individual. Normal:
Adults: 10-20 μg 1-2 x dly; child: 5-10
μg 1-2 x dly. Internasal instill. See lit.
NASAL SPRAY: 5 ml x 0.1 mg/ml. As for
Noct. eneur., cranial diabetes insip.,
Cranial diabetes insip., noct. enur., tmt.
nocturia in adults assoc. with noct.