All the Active Ingredient Drugs
Prostaglandin. Alprostadil 0.5 mg/ml. AMPS: 1 ml. I.A. or I.V. For admin, by IV drip or constant rate infus. pump.
The infus. is gener. init. at a rate of 0.05- 0.1 mcg alprostadil/kg/min. The most experience has been with 0.1 mcg/kg/min. After a therap. response (an incr. in pO2 in neonates with restricted pulm. blood flow or an incr. in system. blood press. and blood pH in neonates with restrict. system. blood flow) has been obtained, the infus. rate should be reduced to the lowest possible dosage that will maintain the desired response. See lit.
For palliative ther. to maintain the patency of the ductus arteries.