Prostaglandin

10 Drugs classified under this drug class

Prostaglandin, β Blocker. Bimatoprost 0.3 mg/ml, Timolol Maleate 5 mg/ml.
BOTTLE: 3 ml. 1 dr.×1/d, in the morn. or in the eve., in each eye that requires tmt.
Reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.
C/I: Hypersens. to bimatoprost, timolol, beta block. Pts. with respirat. disord. such as asthma or severe COPD. Patients with cardiac disorders such as bradycardia, heart block or heart failure. Lact.

Prostaglandin. Alprostadil 10 mcg, 20 mcg.
VIAL: 1 x 10 μg, 20 μg sterile pwd. + 1 ml
diluent (in a prefilled syringe). Direct
intracavernosal inject. See lit.
Erectile dysfunct., adjunct. to diagn.
erectile dysfunct.
C/I: Hypersens., pts. with predispos. to
priapism.

Prostaglandin. Epoprostenol (as sodium) 0.5 mg, 1.5 mg.
VIAL (freeze-dried pwdr.): 1 + 1 sterile
diluent. See lit.
Long-term I.V. tmt. prim. pulm.
hypertens. in NYHA class III and IV.

Prostaglandin. Iloprost 0.1 mg/ml.
AMPS (Conc. sol. for infus.): 0.5 ml.
See lit.
Periph. art. occlus. dis. (stage III and IV)
in adv. arterioscler., diabet. angiopath.,
thromboangit. obliterans (Buerger’s dis.),
Raynaud’s syndr.
C/I: Pregn., lact., hypersens. to compon.,
where effect of drug on platelets might
incr. risk of hemorrh., (e.g., active pept.
ulc., trauma, intracran. hemorrh.), severe
coron. heart dis., unstable ang., M.I.
within last 6 mths., acute or chron.
congest. heart fail., severe arrhyth.
suspect. pulm. congest.

Prostaglandin. Dinoprostone 10 mg.
S.R. VAG. PESS. (with retrieval system): 5.
Releases 0.3 mg/hr. 1 insert positioned
behind post vag. fornix. If ripening
within 12 hrs., remove. No more than 2
consecutive inserts.
Initiat. and/or continuat. of cervical
ripening in patients at term, from 37th
week of gestation, with bishop score of 6
or less.

Prostaglandin. Dinoprostone 1 mg / 3 g.
VAG. GEL: 3 g x 1 mg, 2 mg. Initial: 1 mg. The pt. should remain in supine pos. for at least 30 min. Aft 6 hrs: A second dose of 1 mg or 2 mg, if necessary.
Therapeutic termination of pregnancy, missed abortion.
C/I: Hypersens. Pts. with hypersens. to prostaglandins. Pts. in whom oxytocic drugs are generally contra-indicated or where prolong. contractions of the uterus are consid. inappropriate such as: Cases with a history of Caesarean sec. or major uterin. surg.; Cases where there is evidence of a potent. for obstruct. labour.
In pts. with a past history of, or existing, pelvic inflamm. dis., unless adequate prior tmt. has been instituted.
Pts. with active cardiac, pulmon., renal or hep.dis.