All the Drug Class Drugs
Prostaglandin. Iloprost 0.1 mg/ml. AMPS (Conc. sol. for infus.): 0.5 ml.
Periph. art. occlus. dis. (stage III and IV)
in adv. arterioscler., diabet. angiopath.,
thromboangit. obliterans (Buerger’s dis.),
C/I: Pregn., lact., hypersens. to compon.,
where effect of drug on platelets might
incr. risk of hemorrh., (e.g., active pept.
ulc., trauma, intracran. hemorrh.), severe
coron. heart dis., unstable ang., M.I.
within last 6 mths., acute or chron.
congest. heart fail., severe arrhyth.
suspect. pulm. congest.
Prostaglandin. Dinoprostone 10 mg. S.R. VAG. PESS. (with retrieval system): 5.
Releases 0.3 mg/hr. 1 insert positioned
behind post vag. fornix. If ripening
within 12 hrs., remove. No more than 2
Initiat. and/or continuat. of cervical
ripening in patients at term, from 37th
week of gestation, with bishop score of 6
Prostaglandin. Dinoprostone 10 mg/ml. AMPS: 1 x 0.5 ml (alcohol. sol.). Extraamniot.
use for ther. term. pregn. (100
μg/ml). Adapt. to pt. response. Prepare
sol. cont. 100 μg/ml using diluent
provided. Subseq. instils. vary 1
ml-2ml (usually 2 ml) accord. uterine
response. 2 hrs to elapse betw. instils.
(Never less than 1 hr). Max. cont.
admin: Not more than 2 days.
Ther. abort. 1st/2nd trimester; evac.
uterus missed abort; alt. to complete
ther. terminat. when intra-amniot. saline
injects. failed. Extra-amniot. route more
effect. and better tolerat. than I.V. route.
C/I: Hypersens., not to use extra-amniot.
route in cervicitis/vag. infects. Pts
already receiv. I.V. oxytocic drugs.
Prostaglandin. Dinoprostone 1 mg / 3 g. VAG. GEL: 3 g x 1 mg, 2 mg.
Initial: 1 mg. The pt. should remain in
supine pos. for at least 30 min. Aft 6
hrs: A second dose of 1 mg or 2 mg, if
For labour induct. in term and near term
pregn. women who have favor. induct.
features and who have a singleton
pregn. with vertex present.
C/I: Hypersens. to prostaglandins or
other constituents of the gel.
For pts. in whom oxytocic drugs are
general. contra-indicated or where
prolong. contract. of the uterus are
consid. inappropr. such as:
Cases with a hist. of Caesarean sect. or
major uter. Surg.; Cases where there is
cephalopelvic disproport.; Cases in
which fetal malpresentat. is present;
Cases where there is clinical suspic. or
definite evidence of pre-existing fetal
distress; Cases in which there is a history
of difficult labour and/or traumat. deliv.;
Grand multiparae with over five prev. term pregnan.; Pts. with ruptured
In pts. with a past hist. of, or exist.,
pelvic inflamm. dis., unless adequate
prior tmt. has been instituted.
In pts. where there is clinic. suspic. or
definite evid. of placenta praevia or
unexplain. vaginal bleed. during this
Pts. with active cardiac, pulmonary,
renal or hepatic dis