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  • ACE Inhibitor
    11 Drugs classified under this drug class

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    ACE Inhibitor. Captopril 12.5, 25, 50 mg.
    TABS: 90 x 12.5 mg, 25 mg, 50 mg. Max.
    dly. dose: 150 mg. Hypertens: Initial:
    25-50 mg 2 x dly in div. doses. Incr.
    intervals at least 2 wks: 100-150 mg dly
    in div. doses to reach target BP. Heart
    fail: Initial: 6.25-12.5 mg BID or TID.
    Titrat. to maint. dose (75-150 mg dly) at
    intervals of at least 2 wks. depen. on pt.
    response. Type 1 diabet. nephropathy:
    75-100 mg dly in div doses. MI, ren.
    impair., child, adolesc: See lit.
    Hypertens., C.H.F., insulin depend. diabet.
    nephropathy in hypertens./nonhypertens.
    pts. when serum creatinine
    level < 2.5 mg/dl. Left ventric. dysfunct.
    post MI. To improve survival follow. MI in
    clinic. stable pts. with left ventric.
    dysfunct. manifest. as eject. fract. < or
    equals 40% and to reduce incidence of
    overt heart fail. and subseq. hospitalizat.
    for C.H.F. in these patients.
    C/I: Pregn., lact., hypersens., former
    reacts. incl. swell. face, hands, lips,
    tongue of unknown origin. See lit.

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    ACE Inhibitor. Cilazapril 1, 2.5, 5 mg.
    TABS: 28 x 1 mg, 2.5 mg, 5 mg. Essent.
    hypertens: 1.25 mg 1 x dly for first 2
    days. Maint: 2.5-10 mg 1 x dly. adjust.
    accord. pt. response. Renovasc. hypertens.
    Initial: 0.5 mg 1 x dly. under close
    med. vision. Maint: Accord. to
    response. C.H.F: Initial: 1 mg dly.
    Maint: 1 - 2.5 mg 1 x dly. Adjust.
    accord. pt. response.
    Essential and renal hypertens., C.H.F.
    C/I: Ascites, pregn., lact.

    Cilaril Plus
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    Multiple ingredients
    Cilaril Plus

    ACE Inhibitor, Thiazide. Cilazapril 5 mg, Hydrochlorothiazide 12.5 mg.
    TABS: 28. 1 tab dly.
    Essential hypertens. in patients who
    have been stabilized on individual
    components given in the same
    C/I: Pregn., lact.

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    ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg.
    TABS: 30x5mg, 10mg, 20mg. Hypertens.: Initial: usually 5-20 mg 1 x dly. Dose of 5 mg or lower may be indicated in cases such as strongly activated renin-angiotensin-aldosterone syst. prior tmt. with high doses diuretics. See lit. Mainten.: usually 20 mg dly, max. maint. dose: 40 mg dly.
    HF/asymptom. left ventr. dysfunct.: Initial 2.5 mg, incr. gradual.
    Mainten.: 20mg in single dose/2 div. doses. Max: 40mg in 2 div. doses. See lit.
    For dosage in renal insuffic./elderly/paediatrics: see lit.
    Tmt. of essent. hypertens., renovasc. hypertens., CHF, to reduce mortal. in all degrees HF. To retard develop. of symptom. HF In asymptom. pts. with left ventric. dysfunc.
    C/I: Hypersens. Hypersens. to other ACE inhib.; hist. of angioedema assoc. with previous ACE-inhib. ther., hered. idiopath. angioedema; 2nd, 3rd trim. of preg.; concom. use with aliskiren contain. product in pts. with diab. mell. or renal impair. (GFR <60ml/min/1.73 m2); comb. with sacubitril/valsartan.
    Administrat. of enalapril within 36 hrs. of switching to or from sacubitril/valsartan. See lit.

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    ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg.
    TABS: 30. See lit.
    Essential hypertens., renovasc.
    hypertens., CCF, reduce mortality in pts.
    with all degrees heart fail., retard
    develop. sympt. heart fail. in asympt. pts.
    with left ventric. dysfunct.

    Ramipril Plus Teva
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    Multiple ingredients
    Ramipril Plus Teva

    ACE Inhibitor, Thiazide. Hydrochlorothiazide 12.5 mg, 25 mg, Ramipril 2.5 mg, 5 mg.
    SCORED TABLETS: 30. Accord. desired
    antihypertens. effect and pt’s tol. to the
    drug. Initial: 2.5 mg ramipril/12.5 mg
    HCT, If necess., dose may incr. at
    intervals of 2-3 wks. Max. dly dose: 10
    mg ramipril/50 mg HCT. Admin. in
    morn. as single dose. In most cases,
    blood press. will fall suffic. after 2.5 mg
    ramipril/12.5 HCT or 5 mg ramipril/25
    mg HCT dly. Pts pre-treated with
    diuretics: Discont. diuret. at least 2-3
    days bef. start. tmt or at least reduc.
    diuret. If discont. imposs., initiate tmt.
    with smallest possible dose (1.25 mg)
    dly in free combinat. Subsequent.
    change to dly dose of max. 2.5 mg
    ramipril/ 12.5 mg HCT. Ren. impair. pts:
    Creatinine clear. 60-30 ml/min/1.73 m2
    body surface: Initial: ramipril alone:
    1.25 mg dly. Aft. grad. incr. dose, start
    combinat. prep: with 2.5 mg
    ramipril/12.5 mg HCT dly. Max dly
    dose: 5 mg ramipril/25 mg HCT. Impair.
    liver funct: Response to tmt. may be
    increased/reduced. Tmt. must
    therefore be initiated only under close
    medic. vis. Max. dly dose: 2.5 mg. Tabs.
    to be swallowed whole with liq.
    (approx. 1/2 glass) before/during/after
    meal. Not to be chewed or crushed.
    Not for child.
    Essent. hypertens. when blood press.
    cannot be adeq. lowered with ramipril
    C/I: Hypersens. to ramipril, any other ACE
    inhib., HCT, other thiazide diuret.,
    sulfonamides, any other ingred. of the
    prep. History angioneurot. edema;
    severe impair. ren. funct; dialysis pts, pts.
    with hemodynamic. relevant ren. art.
    stenos., bilat./unilat. in the single kidney.
    Pts. with hemodynamic. relevant leftventric.
    inflow/outflow imped. (e.g.
    stenos. aort./mitral valve); pts. with clinic.
    relevant electrolyte disturbs. which may
    worsen follow. tmt, e.g. hypokalem.,
    hyponatrem., hypercalcem., severe
    impair. liver funct., pregn., lact., concom.
    use ACE inhibit., extracorporeal tmt. lead. to contact of blood with negatively
    charged surfaces must be avoided (may
    lead to severe anaphylact. react.). Such
    tmts incl: dialysis or hemofiltrat. with
    certain high-flux membranes and low
    density lipoprotein apheres. with
    dextran sulfate.