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  • ACE Inhibitor
    12 Drugs classified under this drug class


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    Aceril
    Dexcel
    RX
    full basket chart
    Aceril

    ACE Inhibitor. Captopril 12.5, 25, 50 mg.
    TABS: 90 x 12.5 mg, 25 mg, 50 mg. Max.
    dly. dose: 150 mg. Hypertens: Initial:
    25-50 mg 2 x dly in div. doses. Incr.
    intervals at least 2 wks: 100-150 mg dly
    in div. doses to reach target BP. Heart
    fail: Initial: 6.25-12.5 mg BID or TID.
    Titrat. to maint. dose (75-150 mg dly) at
    intervals of at least 2 wks. depen. on pt.
    response. Type 1 diabet. nephropathy:
    75-100 mg dly in div doses. MI, ren.
    impair., child, adolesc: See lit.
    Hypertens., C.H.F., insulin depend. diabet.
    nephropathy in hypertens./nonhypertens.
    pts. when serum creatinine
    level < 2.5 mg/dl. Left ventric. dysfunct.
    post MI. To improve survival follow. MI in
    clinic. stable pts. with left ventric.
    dysfunct. manifest. as eject. fract. < or
    equals 40% and to reduce incidence of
    overt heart fail. and subseq. hospitalizat.
    for C.H.F. in these patients.
    C/I: Pregn., lact., hypersens., former
    reacts. incl. swell. face, hands, lips,
    tongue of unknown origin. See lit.

    Cilaril
    Unipharm
    RX
    partial basket chart
    Cilaril

    ACE Inhibitor. Cilazapril 1, 2.5, 5 mg.
    TABS: 28 x 1 mg, 2.5 mg, 5 mg. Essent.
    hypertens: 1.25 mg 1 x dly for first 2
    days. Maint: 2.5-10 mg 1 x dly. adjust.
    accord. pt. response. Renovasc. hypertens.
    Initial: 0.5 mg 1 x dly. under close
    med. vision. Maint: Accord. to
    response. C.H.F: Initial: 1 mg dly.
    Maint: 1 - 2.5 mg 1 x dly. Adjust.
    accord. pt. response.
    Essential and renal hypertens., C.H.F.
    C/I: Ascites, pregn., lact.

    Cilaril Plus
    Unipharm
    RX
    partial basket chart
    Multiple ingredients
    Cilaril Plus

    ACE Inhibitor, Thiazide. Cilazapril 5 mg, Hydrochlorothiazide 12.5 mg.
    TABS: 28. 1 tab dly.
    Essential hypertens. in patients who
    have been stabilized on individual
    components given in the same
    proportions.
    C/I: Pregn., lact.

    Enaladex
    Dexcel
    RX
    full basket chart
    Enaladex

    ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg.
    TABS: 30×5mg, 10mg, 20mg.
    Hypertens.: Initial: usuall. 5- 20 mg 1 x
    dly. Lower dose may be indic. in cases
    such as strong active. rennin
    -angiotens. -aldosterone syst., prior
    tmt. with high doses diuretics. See lit.
    Maint.: usual. 20 mg dly, max. mait.
    Dose: 40 mg dly. Heart fail./asympt.
    Left ventric. Dyfunct: Init. 2.5 mg, incr.
    graduall.To maint: 20mg single dose/2
    div. doses. Max: 40mg in 2 div. doses.
    See lit. For dosage in renal insuffic./
    elderly/paediat. see lit.
    Tmt. of essnt. hypertens., renovascular
    hypertens. congest. heart fail. and to
    reduce mortal.in pts. with all degrees of
    heart fail. To retard the develop. of sympt.
    heart fail. in asympt. pts. with left ventric.
    dysfunct.
    C/I: Hypersens. to enalapril or to any of
    the ingred. or other ACE inhib. History of
    angioedema assoc. with previous ACEinhib.
    ther., hered. idiopath. angioed.
    2nd, 3rd trim. pregn. Concom. use with
    aliskiren contain. product in pts. with
    diab. mell. or ren. impair. (GFR <60ml/
    min/1.73 m2). See lit.

    Enalapri
    CTS
    RX
    full basket chart
    Enalapri

    ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg.
    TABS: 30. See lit.
    Essential hypertens., renovasc.
    hypertens., CCF, reduce mortality in pts.
    with all degrees heart fail., retard
    develop. sympt. heart fail. in asympt. pts.
    with left ventric. dysfunct.

    Ramipril Plus Teva
    Teva
    RX
    partial basket chart
    Multiple ingredients
    Ramipril Plus Teva

    ACE Inhibitor, Thiazide. Hydrochlorothiazide 12.5 mg, 25 mg, Ramipril 2.5 mg, 5 mg.
    SCORED TABLETS: 30. Accord. desired
    antihypertens. effect and pt’s tol. to the
    drug. Initial: 2.5 mg ramipril/12.5 mg
    HCT, If necess., dose may incr. at
    intervals of 2-3 wks. Max. dly dose: 10
    mg ramipril/50 mg HCT. Admin. in
    morn. as single dose. In most cases,
    blood press. will fall suffic. after 2.5 mg
    ramipril/12.5 HCT or 5 mg ramipril/25
    mg HCT dly. Pts pre-treated with
    diuretics: Discont. diuret. at least 2-3
    days bef. start. tmt or at least reduc.
    diuret. If discont. imposs., initiate tmt.
    with smallest possible dose (1.25 mg)
    dly in free combinat. Subsequent.
    change to dly dose of max. 2.5 mg
    ramipril/ 12.5 mg HCT. Ren. impair. pts:
    Creatinine clear. 60-30 ml/min/1.73 m2
    body surface: Initial: ramipril alone:
    1.25 mg dly. Aft. grad. incr. dose, start
    combinat. prep: with 2.5 mg
    ramipril/12.5 mg HCT dly. Max dly
    dose: 5 mg ramipril/25 mg HCT. Impair.
    liver funct: Response to tmt. may be
    increased/reduced. Tmt. must
    therefore be initiated only under close
    medic. vis. Max. dly dose: 2.5 mg. Tabs.
    to be swallowed whole with liq.
    (approx. 1/2 glass) before/during/after
    meal. Not to be chewed or crushed.
    Not for child.
    Essent. hypertens. when blood press.
    cannot be adeq. lowered with ramipril
    alone.
    C/I: Hypersens. to ramipril, any other ACE
    inhib., HCT, other thiazide diuret.,
    sulfonamides, any other ingred. of the
    prep. History angioneurot. edema;
    severe impair. ren. funct; dialysis pts, pts.
    with hemodynamic. relevant ren. art.
    stenos., bilat./unilat. in the single kidney.
    Pts. with hemodynamic. relevant leftventric.
    inflow/outflow imped. (e.g.
    stenos. aort./mitral valve); pts. with clinic.
    relevant electrolyte disturbs. which may
    worsen follow. tmt, e.g. hypokalem.,
    hyponatrem., hypercalcem., severe
    impair. liver funct., pregn., lact., concom.
    use ACE inhibit., extracorporeal tmt. lead. to contact of blood with negatively
    charged surfaces must be avoided (may
    lead to severe anaphylact. react.). Such
    tmts incl: dialysis or hemofiltrat. with
    certain high-flux membranes and low
    density lipoprotein apheres. with
    dextran sulfate.

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