All the Active Ingredient Drugs
ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg. TABS: 30x5mg, 10mg, 20mg. Hypertens.: Initial: usually 5-20 mg 1 x dly. Dose of 5 mg or lower may be indicated in cases such as strongly activated renin-angiotensin-aldosterone syst. prior tmt. with high doses diuretics. See lit. Mainten.: usually 20 mg dly, max. maint. dose: 40 mg dly.
HF/asymptom. left ventr. dysfunct.: Initial 2.5 mg, incr. gradual.
Mainten.: 20mg in single dose/2 div. doses. Max: 40mg in 2 div. doses. See lit.
For dosage in renal insuffic./elderly/paediatrics: see lit.
Tmt. of essent. hypertens., renovasc. hypertens., CHF, to reduce mortal. in all degrees HF. To retard develop. of symptom. HF In asymptom. pts. with left ventric. dysfunc.
C/I: Hypersens. Hypersens. to other ACE inhib.; hist. of angioedema assoc. with previous ACE-inhib. ther., hered. idiopath. angioedema; 2nd, 3rd trim. of preg.; concom. use with aliskiren contain. product in pts. with diab. mell. or renal impair. (GFR <60ml/min/1.73 m2); comb. with sacubitril/valsartan.
Administrat. of enalapril within 36 hrs. of switching to or from sacubitril/valsartan. See lit.
ACE Inhibitor. Enalapril Maleate 5, 10, 20 mg. TABS: 30. See lit.
Essential hypertens., renovasc.
hypertens., CCF, reduce mortality in pts.
with all degrees heart fail., retard
develop. sympt. heart fail. in asympt. pts.
with left ventric. dysfunct.
ACE Inhibitor, Calcium Channel Blocker. Lercanidipine HCl 10, Enalapril Maleate 10, 20. FC Tabs: 10 mg/10 mg, 10mg/20mg. Tmt. of essent. hypertens. in pts. not contr. by lercanadipine monother.
C/I: See lit.
ACE Inhibitor, Calcium Channel Blocker. Enalapril Maleate 10 mg, 20 mg, Lercanidipine HCl 10 mg. TABS: 30. 1 tab × dly. at least 15 mins.
bef. meal, if BP cannot be control. by
either Lercanidipine or enalapril.
Elderly: Depend on kidney funct.
Child/adolesc.<18yrs: Not recommend.
See lit.
Combo 10: Tmt. essent. hypertens. not
control. with lercanidipine alone.
Combo 20: Tmt. Essent. Hypertens. Not
control. With enalapril alone.
C/I: Hypersens. to active subs., excips,
other ACE inhib. Pregn., lact.
Uncontrol. CHF. Left ventric. outflow
tract obstruct. Unstable ang. pect. (at
rest or progress. incr.) Pts. within 1 m.
after MI. Severe ren.,/hepat. impair.
Concom. use with antifungals,
macrolides, antivirals, cyclosporine,
Grapefruit/ grapefruit juice. Assoc. with
aliskiren-contain. meds. in pts. with diab.
mell. or ren. impair., facial edema, lips,
tongue/throat, hands, feet (heredit./
associat. with use of ace inhib.): tissue
swell (heredit. trend. /unknown origin).
See lit.