Calcium Channel Blocker

15 Drugs classified under this drug class

Calcium Channel Blocker, Class IV Antiarrhythmic. Diltiazem (as HCl) 120, 180, 240 mg.
C.R. CAPS: 30 x 120 mg, 180 mg, 240 mg.
Usual start. dose: 240 mg 1 x dly. All
strengths 1 x dly. See lit.
Chron. stable ang. pect., ang. due to
coronary art. spasm, hypertens.
C/I: Sick-sinus syndr., 2nd or 3rd degree
AV block (unless funct. ventric.
pacemaker present), severe bradycard.,
severe heart fail., severe hypotens. (syst.
press. < 90 mm Hg), acute M.I.,
radiograph. pulm. congest.

Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg.
TAB: 20, 30. Hypertens. and angina: Initial.
5 mg dly, may incr. to max dly dose of
10 mg depend. on pt. response.
Dose titrat. can proceed over 7-14 days
but may proceed more rapidly if clinic.
warranted. No dose adjust. reqd. when
used tog. with thiazide diuret.,
ß-blockers and ACE inhibits. Elderly: As
in younger pts. Child: Safety and effect.
have not been established.
Mild to mod. hypertens., chron. stable
ang., confirmed or susp. vasospastic ang.
(Prinzmetal’s or variant ang.). May be
used alone or in combin. with other
antihypertens. or antiang. agents.

Calcium Channel Blocker. Amlodipine Maleate 5 mg, 10 mg.
TABS: 20. Initial: 5 mg 1 x dly. May incr.
to max. 10 mg dly depend. on pt.
response. Elderly and young pts:
Normal dosage regimen.
Mild to mod. hypertens., vasospastic
angina (Prinzmetal’s or variant angina),
chronic stable angina.

Calcium Channel Blocker, Class IV Antiarrhythmic. Diltiazem HCl 120 mg.
S.R. TABS: 30. 1 tab 2 x dly to be adjust.
to pt. req.
Chron. stable ang. pect., ang. due to
coron. art. spasm, hypertens.

Calcium Channel Blocker, Class IV Antiarrhythmic. Diltiazem (HCl) 30 mg.
TABS: 30 x 30 mg. Initial. 30 mg 4
x dly, bef. meals and at bedt. Grad. incr.
at 1-2 day intervals to 240 mg in equal,
div. doses 3-4 x daily, until opt.
response obtained. Subling.
nitroglycerin may be taken as req. May
be co-admin. with short- and longacting
nitrates. Hepat./ren,. impair:
Titrate with caution.
Ang. pect.
C/I: Hypersens., sick sinus syndr., 2nd or
3rd degree AV block, except in presence of funct. ventric. pacemaker; hypotens.
(<90 mm Hg systol.); acute MI and pulm.
congest., document. by X-ray.

Angiotensin II Antagonist, Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg, Valsartan 80 mg, 160 mg.
F.C. TABS: 14, 28 x 5 mg/80 mg, 5 mg/160 mg, 10 mg/160 mg. 1 tab. dly. with/ without food. Individ. dose titrat. recommend. bef. change to fixed dose comb. See lit.
Indicated for pts. whose blood pressure is not adequat. controlled on monother.
C/I: Hypersens. to the active substance., or to dihydropyridine derivat.
Sev. hep. impair., biliary cirrhos. or cholestasis.
Concom. use with aliskiren-contain. products in pts. with diabetes mell. or renal impair. (GFR <60 ml/min/1.73 m²).
2^nd and 3^rd trimesters of preg.
Severe hypotens.
Shock (include. cardiogen. shock).
Obstruct. of the outflow tract of the left ventricle (e.g. hypertrop. obstruct. cardiomyopathy and high grade aortic stenosis).
Haemodynamic. unstable HF after acute MI.