All the Active Ingredient Drugs
Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg. TAB: 20, 30. Hypertens. and angina: Initial.
5 mg dly, may incr. to max dly dose of
10 mg depend. on pt. response.
Dose titrat. can proceed over 7-14 days
but may proceed more rapidly if clinic.
warranted. No dose adjust. reqd. when
used tog. with thiazide diuret.,
ß-blockers and ACE inhibits. Elderly: As
in younger pts. Child: Safety and effect.
have not been established.
Mild to mod. hypertens., chron. stable
ang., confirmed or susp. vasospastic ang.
(Prinzmetal’s or variant ang.). May be
used alone or in combin. with other
antihypertens. or antiang. agents.
Angiotensin II Antagonist, Plain Combinations with Dihydropyridine Derivatives. Amlodipine Besylate 5 mg, 10 mg, Valsartan 80 mg, 160 mg. COATED TABS.: 28 x 5 mg/80 mg,
5 mg/160mg; 10 mg/160 mg.
1 tab dly. Individ. dosetitrat. with
components recommend. before changingto fixed dose comb.Max. dose is 10/320 mg.
Tmt. of essential hypertens., for pts.
whose blood pressure is not adeq.
controlled on monotherapy.
C/I: Hypersens.toamlodopine, valsartan,
todihydropyridinederivat.; Severe hep.
impair., cholestasis; Severe renal impair.
and pts. underg. dialysis;
Preg.; Concom. use of ARBs or ACEIs with
aliskiren in pts. with diabet.
Angiotensin II Antagonist, Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg, Valsartan 80 mg, 160 mg. F.C. TABS: 14, 28 x 5 mg/80 mg, 5 mg/160 mg, 10 mg/160 mg. 1 tab. dly. with/ without food. Individ. dose titrat. recommend. bef. change to fixed dose comb. See lit.
Indicated for pts. whose blood pressure is not adequat. controlled on monother.
C/I: Hypersens. to the active substance., or to dihydropyridine derivat.
Sev. hep. impair., biliary cirrhos. or cholestasis.
Concom. use with aliskiren-contain. products in pts. with diabetes mell. or renal impair. (GFR <60 ml/min/1.73 m²).
2nd and 3rd trimesters of preg.
Severe hypotens.
Shock (include. cardiogen. shock).
Obstruct. of the outflow tract of the left ventricle (e.g. hypertrop. obstruct. cardiomyopathy and high grade aortic stenosis).
Haemodynamic. unstable HF after acute MI.
Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg. TABS: 20, 30 x 5 mg, 10mg. Initial: 5 mg 1 x dly. Can incr. to max. 10 mg dly. depend. on pt. response.
Mild to mod. hypertens, chron. stable angina, vasospastic angina (Prinzmetal’s or variant angina).
C/I: Hypersens. to dihydropyridine derivat., amlodipine. Sev. hypotension. Shock (includ.. cardiogen. shock). Obstruct. of the outflow tract of the left ventricle (e.g., high grade aortic stenosis). Haemodynam. unstab. HF after acute MI.