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  • Valsartan
    8 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

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    Co-Diovan
    Novartis
    RX
    partial basket chart
    Multiple ingredients
    Co-Diovan

    Angiotensin II Antagonist, Thiazide. Valsartan 80 mg, 160 mg, Hydrochlorothiazide 12.5 mg, 25 mg.
    CO-DIOVAN 80: F.C. TABS: 28. 1 tab dly. Max. effect within 2-4 wks.
    Hypertens. when comb. ther. appropriate.
    CO-DIOVAN 160: F.C. TABS: 28. 1 tab dly.
    Hypertens., when blood pressure not adequat. controlled by monother. To be used as second-line ther.
    C/I: Hypersens. Hypersens. to sulfonamide-derived med. products. 2nd & 3rd trim. of preg. Biliary cirrhos. and cholestasis. Pts. with anuria. Refractor. hypokalaemia, hyponatraemia, hypercalcaemia, and symptomat. hyperuricaemia. Concom. use with aliskiren-contain. products in pts. with diab. mell. or renal impair. (GFR <60 mL/min/1.73m²).

    Diovan
    Novartis
    RX
    partial basket chart
    Diovan

    Angiotensin II Antagonist. Valsartan 40, 80 ,160 mg.
    F.C. TABS.: 28. Hyperten.: 80 mg×1/d most
    pts. The antihypertens. effect is
    substantial. present within 2 wks. and
    max. effects are seen after 4 wks.
    In some pts. whose blood press. is not
    adequate. control., the dose may be
    incr. to 160 mg, or a greater decr. in BP
    may be achieved by add. in a thiazide
    diuret. See lit.
    Heart fail.: 40 mg ×1/d.
    Uptitration to 80 mg, 160 mg×2/d
    should be done to the highest dose
    tolerat. by the pt.
    Considerat. should be given to
    reducing the dose of concom. diuret.
    The max. dly. dose admin. in clin. trials
    is 320 mg in divided doses. See lit.
    Post-MI.: Achievem. of the target dose
    of 160 mg×2/d should be based on the
    pt’s tolerab. to valsartan during titrat. If
    symptomat. hypotension or renal
    dysfunct. occurs, consider. should be
    given to a dosage reduct. See lit.
    Therapy may be init. as early as 12 hrs.
    after a MI . After an initial dose of 20 mg ×2/ d, valsartan ther. should be
    titrated to 40 mg, 80 mg, and 160 mg
    ×2/ d over the next few wks. The start.
    dose is provided by the 40 mg divisible
    tab.
    Tmt. of hypertens.: 80 mg and 160 mg.
    Heart fail. : 40 mg, 80 mg and 160 mg
    Tmt. of heart fail.(NYHA class II‐IV) in pts.
    who are intoler. of angiotens. Convert.
    enzyme inhib. See lit.
    Post-myocard. infarction (40 mg, 80 mg
    and 160 mg)
    Indicat. to improve survival follow.
    myocard.l infarct.in clinical. stable pts.
    with signs, sympt. or radiolog. evidence
    of left ventric. fail. and/or with left
    ventric. systolic dysfunct. See lit.
    C/I: Known hypersens. to valsartan or to
    any of the excip. Preg., and lact.
    Sev. hepatic impair., cirrhosis, biliary
    obstruct. Concom. use of angiotensin
    recept. antagonists (ARBs) ‐ includ.
    valsartan ‐ or of ACEIs with aliskiren is
    contraind. in pts. with diab. mell. or renal
    impair.(GFR < 60 ml/min/1.73 m²). See
    lit.

    Duplex
    Unipharm
    RX
    not in the basket chart
    Multiple ingredients
    Duplex

    Angiotensin II Antagonist, Plain Combinations with Dihydropyridine Derivatives. Amlodipine Besylate 5 mg, 10 mg, Valsartan 80 mg, 160 mg.
    COATED TABS.: 28 x 5 mg/80 mg,
    5 mg/160mg; 10 mg/160 mg.
    1 tab dly. Individ. dosetitrat. with
    components recommend. before changingto fixed dose comb.Max. dose is 10/320 mg.
    Tmt. of essential hypertens., for pts.
    whose blood pressure is not adeq.
    controlled on monotherapy.
    C/I: Hypersens.toamlodopine, valsartan,
    todihydropyridinederivat.; Severe hep.
    impair., cholestasis; Severe renal impair.
    and pts. underg. dialysis;
    Preg.; Concom. use of ARBs or ACEIs with
    aliskiren in pts. with diabet.

    Entresto
    Novartis
    RX
    partial basket chart
    Multiple ingredients
    Entresto

    Angiotensin II Antagonist, Other Combinations. Sacubitril 24, 49, 97 mg, Valsartan (as sodium salt complex) 26, 51, 103 mg.
    F.C. TABS: 28×50 mg, 56×100 mg, 56×200 mg. Init. dose: 1 tab (100 mg)×2/d, The dose should be doubled (in certain situation.) after 2-4 wks. to the target maint. dose of 1 tab. of 200 mg twice dly., as tolerated by the pt. See lit.
    Tmt. of heart fail. (NYHA class II-IV) in pts. with syst. dysfunc. This formulation has been shown to reduce the rate of cardiovasc. death and heart fail. hospitalis. compared to ACE inhib. therapy.
    C/I: Hypersens. Concom. use with ACE inhib. , ust not be admin. until 36 hrs. after discount. ACE inhib. ther. Known hist. of angioed.related to prev.ACE inhib. or ARB therapy. Hered. or idiopath. angioed. Concom. use with aliskiren-contain. med. products in pts. with diabetes mell. or in pts. with renal impair. (eGFR <60 ml/min/1.73 m2). Severe hep. impair., biliary cirrhosis and cholestasis. 2nd, 3rd trimes. of preg. Pts. with serum K+ level >5.4 mmol/l or with SBP <100 mmHg.

    Exforge
    Novartis
    RX
    not in the basket chart
    Multiple ingredients
    Exforge

    Angiotensin II Antagonist, Calcium Channel Blocker. Amlodipine Besylate 5 mg, 10 mg, Valsartan 80 mg, 160 mg.
    F.C. TABS: 14, 28 x 5 mg/80 mg, 5
    mg/160mg, 10 mg/160 mg. 1 tab dly
    with or without food. Individ. dose
    titrat. recommend. bef. change to fixed
    dose comb.
    Essential hypertens. not adeq. controlled
    on monother.
    C/I: Known hypersens.to amlodopine,
    valsartan, to dihydropyridine derivat.
    Sev. hep. impair. bil. chirrhos., cholestas.
    Sev. ren. impair.(GFR < 30 ml/min/1.73
    m2),pts. underg. dialys., Preg. ., concom.
    use with aliskiren in pts. with diab.
    mellit.or ren.impair.(GFR < 60 ml/
    min/1.73 m2).

    Valsartan Dexcel 80, 160
    Dexcel
    RX
    partial basket chart
    Valsartan Dexcel 80, 160

    Angiotensin II Antagonist. Valsartan 80 mg, 160 mg.
    F.C TAB.: 28. Hypertens.: The recomm. dose
    of Valsartan is 80 mg ×1/d for most pts.
    The antihypertens. effect is substant.
    present within 2 wks. and max. effects
    are seen after 4 wks. In some pts.
    whose blood pres. is not adequate.
    control. the dose may be increased to
    160 mg, or a greater decr. in BP may be
    achiev. by add. in a thiazide diur.
    Valsartan may also be admin. with
    other antihypertens. agents.
    Use in pts. over 75 yrs.:
    A lower start. dose of 40 mg once dly. is
    recom.
    Tmt. of HF (NYHA class II-IV) in pts. who
    are intoler. of ACE inhib.
    In a control. clinical trial Valsartan
    signific. reduced hospitalisations for
    heart fail.
    There is no evid. that Valsartan provides
    added benefits when it is used with an
    adequate dose of an ACE inhib.
    Indicated to improve surviv. follow. MI in
    clinical. stable pts. with signs sympt. or
    radiolog. evid. of left ventric. fail. and /or
    with left ventric. systole. dysfunct.
    For tmt. of hypertens.
    C/I: Hypersens. Preg.
    Sev. hep. dis., sev. hep. dysfunc., cirrhosis
    of the hep/ bil. obstruct.
    Pts. with diabetes or impair. renal funct.
    and are concom. taking a antihypertens. formul. contain. aliskiren.

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