Captopril

1 Drug classified under this active ingredient

ACE Inhibitor. Captopril 12.5, 25, 50 mg.
TABS: 90 x 12.5mg, 25mg, 50mg.
Max. dly. dose: 150 mg. Hypertens: Initial: 25-50 mg 2 x dly in div. doses. Incr.
intervals at least 2 wks: 100-150 mg dly in div. doses to reach target BP.
Heart fail.: Init.: 12.5 mg BID or TID.
Titrat. to maint. dose (75-150 mg dly) at intervals of at least 2 wks. depen. on pt. response.
Type 1 diabet. nephropathy: 75-100 mg dly in div doses.
MI, ren. impair., elderly: See lit.
Hypertens., C.H.F., insulin depend. diabet. nephropathy in hypertens./nonhypertens. pts. when serum creatinine level < 2.5 mg/dl. Improve survival follow. MI in clinic. stable pts. with left ventric. dysfunct. manifest. as eject. fract. < or equals 40% and to reduce incidence of overt heart fail. and subseq. hospitalizat. for C.H.F. in these pts.
C/I: Hypersens. Hypersens. to other ACE inhib.
Hist. of angioedema assoc. with previous ACE-inhib. ther., hered. idiopath. angioedema.   2nd, 3rd trim. of preg.
Concom. use with aliskiren contain. product in pts. with diab. mell. or renal impair. (GFR <60ml/min/1.73 m²). See lit.