Who are we?
The Astellas Group’s business philosophy has three elements — raison d’être, mission and beliefs.
Contribute toward improving the health of people around the world through the provision of innovative and reliable pharmaceutical products
- To go beyond all others in exploring and tapping the potential of the life sciences.
- To continue tackling new challenges and creating innovative pharmaceutical products.
- To deliver quality products along with accurate information and retain solid credibility among customers.
- To support healthy living for people around the world.
- To continue shining on the global pharmaceutical field.
Sustainable enhancement of enterprise value
- Astellas will seek to enhance its enterprise value in a sustainable manner.
- Astellas will seek to be the company of choice among all its stakeholders, including its customers, shareholders, employees, and the global community.
- Astellas will strive to gain the trust of all stakeholders and thereby enhance its enterprise value.
Our “beliefs” provide the code of conduct we prize at all times. Astellas will always be a group of people who act upon these beliefs.
High Sense of Ethics
We will always manage our business with the highest sense of ethics.
We will always seek to understand customer needs and our focus will always be on achieving customer satisfaction.
We will not be complacent and will always seek to innovate to create new value.
Our eyes will always be directed to the outside world, and we will continue to create better value faster.
Astellas promises to perform its obligations toward all stakeholders by acting ethically and seeking to actively disclose information.
Drugs Disributed by Astellas Pharma International B.V., Israel
Calcineurin Inhibitors, Immunosuppressant. Tacrolimus 0.5, 1, 3, 5 mg. P.R. HARD CAPS.: 30, 50, 100.
Prophyl. of kidney transplant reject. init.
0.20 - 0.30 mg/kg/d once dly. in the
morning. Administ. should init. within 24
h. after the complet.of surgery.
Prophyl. of liver transplant reject. : init.
0.10 - 0.20 mg/kg/day once dly. in the
morning. Administ. should init. approx.
12-18 h. after the complet. of surgery
Dosage must. be ajust. individ. Once
dly, in the morning, on empty stomach
(at least 1 h. bef. or 2-3 h after a meal).
Prophyl. of transplant reject. in adult
kidney or liver allograft recip. Tmt. of
allograft reject. resistant to tmt. with
other immunosuppres. med. in adult
kidney or liver allograft recip. pts.
C/I: Hypersens., hypersens. to other
Gonadotropin Releasing Hormone Analogues. Leuprorelin Acetate 7.5, 22.5, 45 mg. PRE-FILLED SYR. (1 pwdr. for inj. + 1 solv. cyclic olefin copolymer): 1.
7.5 mg is admin. as a single SC inject. every month. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate for 1 month. 22.5 mg is admin. as a single SC inject. every 3 mnths. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate over a 3 -month period. 45 mg is admin. as a single SC inject. every 6 mnths. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate over a 6 -month period. See lit.
Tmt. of hormone depend. advanced prostate cancer.
C/I: Use in women. Paed. pts. Hypersens. to leuprorelin acetate, to other GnRH agon. In pts. who prev. underwent orchiectomy (as with other GnRH agon., Leuprorelin Acetate does not result in further decr. of serum testoster. in case of surg. castration). As sole tmt. in prostate cancer pts. with spinal cord compres. or evidence of spinal metastases.
Antifungal. Micafungin (as Sodium) 50 mg, 100 mg. GLASS VIAL( pwdr. for sol. for infus.): 1x10ml. Use in adult, adolesc. (≥ 16 yrs.), elderly, Bdy. wt. > 40 kg, Bdy. wt. ≤ 40 kg. Tmt. of invasive candidiasis: 100 mg/d*, Bdy. wt ≤ 40 kg: 2 mg/kg/d*. Tmt. of oesophageal candidiasis: 150 mg/d, Bdy. wt ≤ 40 kg : 3 mg/kg/d. Prophylax. of Candida infect.: 50 mg/d., Bdy. wt ≤ 40 kg: 1 mg/kg/day. *If the pt’s. response is inadeq. , e.g. persist. of cultures/clin. cond. does not improve, the dose may be incr.to 200 mg/d. in pts. wt.> 40 kg or 4 mg/kg/d in pts. ≤ 40 kg.
Adult., adolesc. ≥ 16 yrs. of age & elderly: Tmt. of invasive candidiasis. Tmt. of oesophageal candidiasis in pts. for whom IV ther. is appropriate. Prophylaxis of Candida infec. in pts. undergoing allogeneic haematopoietic stem cell transplant.. Child. (includ. neonates, adolesc. < 16 yrs. of age: Tmt. of invas. candidiasis. Prophylax. of Candida infec. in pts. undergoing allogeneic haematopoietic stem cell transplant. The decision to use Micafungin should take into account a potential risk for the develop. of liver. Micafungin should therefore only be used if other antifungals are not appropriate.
Alkylating Agent. Bendamustine Hydrochloride 25 mg, 100 mg. VIAL (PWDR. CONC. FOR SOL. FOR IFUS.):
1,5×100 mg, 5x25 mg.
For IV infus. over 30-60 min: Monother.
for CLL 100 mg/m² body surface area
1st day and 2nd ; every 4 weeks.
Monother. for indolent non-Hodgkin’s
lymph. refractory to rituximab 120 mg/
m² body surface area on 1st and 2nd;
every 3 weeks. Tmt. should be termin.
or delayed if leukocyte and/or platelet
values drop. to < 3,000/μl or < 75,000/
μl, respectively. Tmt. can be cont. after
leukocyte values have incr.to > 4,000/
μl and platelet values to > 100,000/μl.
1st -line tmt. of CLL (Binet stage B or C) in
pt. for whom fludarabine comb.
chemother. is not appropriate. Indolent
non-Hodgkin’s lymph. as monother. in pts.,
who have progressed during or within 6
months follow. tmt. with rituximab or a
C/I: Hypersens., lact.; Severe hep. impair.
(serum bilirubin > 3.0 mg/dl); Jaundice;
Sev. bone marrow suppres. and sev.
blood count alter. (LEU and/or PLT
values dropped to < 3,000/μl or <
75,000/μl, respectively); Major surgery <
30 days before start of tmt.; Infect.,
especially invol. leukocytopenia; Yellow