All the Drug Class Drugs
Gonadotropin Releasing Hormone Analogues. Leuprorelin Acetate 7.5, 22.5, 45 mg. PRE-FILLED SYR. (1 pwdr. for inj. + 1 solv. cyclic olefin copolymer): 1.
7.5 mg is admin. as a single SC inject. every month. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate for 1 month. 22.5 mg is admin. as a single SC inject. every 3 mnths. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate over a 3 -month period. 45 mg is admin. as a single SC inject. every 6 mnths. The inject. sol. forms a solid med. product deliv. depot and provides cont. release of leuprorelin acetate over a 6 -month period. See lit.
Tmt. of hormone depend. advanced prostate cancer.
C/I: Use in women. Paed. pts. Hypersens. to leuprorelin acetate, to other GnRH agon. In pts. who prev. underwent orchiectomy (as with other GnRH agon., Leuprorelin Acetate does not result in further decr. of serum testoster. in case of surg. castration). As sole tmt. in prostate cancer pts. with spinal cord compres. or evidence of spinal metastases.
