All the Drug Class Drugs
Antineoplastic. Fluorouracil 50 mg / 1 g. CREAM: 20 g. Pre-malignant cond:
Apply thinly to affect. area 1-2 x dly.
Malignant cond: Apply 1-2 x dly under
occlusive dressing where practical.
Should not harm healthy skin. Cont.
tmt. until marked inflamm. resp. from
treated area. Alleviate severe
discomfort with steroid cream. Usual
tmt. 3-4 wks or longer. Healing may
take up to 1-2 months after stopping
ther. Use in child not recommend.
C/I: Hypersens., pregn., lact. co-admin
antiviral nucleoside drugs.
Anti-Androgen, Antineoplastic. Apalutamide 60 mg. F.C. TABS.: 120. 240 mg (four 60 mg tabs.) admin. orally once dly. Swallow the tabs. whole. The drug can be taken with / without food. Pts. should also receive a gonadotropin-releasing hormone (GnRH) analog concur. or should have had a bilater. orchiectomy.
Dose Modific.: If a pt. experiences a greater than or equal to Grade 3 toxic. or an intoler. side effect, hold dosing until sympt. improve to less than or equal to Grade 1 or original grade, then resume at the same dose or a reduced dose (180 mg or 120 mg), if warranted.
Tmt. of pts. with non-metast., castrat.-resist. prostate cancer (NM-CRPC).
Antineoplastic, Immunomodulator Agent. Talimogene Laherparepvec 10^6 PFU/ml, 10^8 PFU/ml. Talimogene laherparepvec, attenuate. herpes S. virus type-1 (HSV-1) derived by funct. deletion of 2 genes (ICP34.5& ICP47) and insert. of coding sequen. for human granulocyte macrophage colony-stimulat. factor (GM-CSF).
106- 1×106 (1 million) plaque form. units (PFU)/mL.
108- 1×108 (100 million) plaque form. units (PFU)/mL
VIAL (sol. for inj.): 1. Dosage must be ajust. individ.
Tmt. of adult. with unresect. melanoma that is regional. or distant. metastat. (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral dis.
C/I: Pts. with a history of hypersens. to talimogene laherparepvec.
Severely immunocompromised pts. (e.g. pts. with severe congen. or acquired cellular and/or humoral immune deficien.).