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  • Talimogene Laherparepvec
    1 Drug classified under this active ingredient

    All the Active Ingredient Drugs

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    Antineoplastic, Immunomodulator Agent. Talimogene Laherparepvec 10^6 PFU/ml, 10^8 PFU/ml.
    Talimogene laherparepvec, attenuate. herpes S. virus type-1 (HSV-1) derived by funct. deletion of 2 genes (ICP34.5& ICP47) and insert. of coding sequen. for human granulocyte macrophage colony-stimulat. factor (GM-CSF).
    106- 1×106 (1 million) plaque form. units (PFU)/mL.
    108- 1×108 (100 million) plaque form. units (PFU)/mL
    VIAL (sol. for inj.): 1. Dosage must be ajust. individ.
    Tmt. of adult. with unresect. melanoma that is regional. or distant. metastat. (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral dis.
    C/I: Pts. with a history of hypersens. to talimogene laherparepvec.
    Severely immunocompromised pts. (e.g. pts. with severe congen. or acquired cellular and/or humoral immune deficien.).