All the Active Ingredient Drugs
Anti-Androgen, Antineoplastic. Apalutamide 60 mg. F.C. TABS.: 120. 240 mg (four 60 mg tabs.) admin. orally once dly. Swallow the tabs. whole. The drug can be taken with / without food. Pts. should also receive a gonadotropin-releasing hormone (GnRH) analog concur. or should have had a bilater. orchiectomy.
Dose Modific.: If a pt. experiences a greater than or equal to Grade 3 toxic. or an intoler. side effect, hold dosing until sympt. improve to less than or equal to Grade 1 or original grade, then resume at the same dose or a reduced dose (180 mg or 120 mg), if warranted.
Tmt. of pts. with non-metast., castrat.-resist. prostate cancer (NM-CRPC).