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  • Substance Dependence
    7 Drugs classified under this biological system

    All the biological system drugs

    Filter by letter: ALL A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
    partial basket chart

    Nicotine Receptor Partial Agonist. Varenicline (as tartrate) 0.5 mg, 1 mg.
    Health basket inclusion: Champix will be given to the treatment of smoking cessation parallel to supportive means.
    TABS: 55 x 0.5 mg, 56 x 1 mg; starter pack: 11 x 0.5 mg + 14, 28 x 1 mg.
    Days 1 – 3: 0.5 mg ×1/d.
    Days 4– 7: 0.5 mg ×2/d.
    Day 8 – end of tmt.: 1 mg ×2/d.
    Pts. should be treated with Varenicline for 12 wks. For pts. who have successf. stopped smok. at the end of 12 wks., an addit. course of 12 wks. tmt. with Varenicline is recomm. to further incr. the likelihood of long-term abstinence.
    Pts. with ren. impair. No dosage adjust. is necessary for pts. with mild- moder. renal impair. For pts. with sev. renal impair. (estimated CrCl <30 mL/min), the recomm. start. dose of Varenicline is 0.5 mg ×1/d. The dose may then be titrated as needed to a max. dose of 0.5 mg×2/d. For  pts. with end-stage renal dis. underg. hemodialysis, a max. dose of 0.5 mg mg×/d may be admin. if toler.
    Aid to smoking cessat. for adults over 18
    C/I: Not to pts. under 18 yrs., hypersens.

    Nicotinell Gum
    full basket chart
    Nicotinell Gum

    Alkaloid. Nicotine 2 mg, 4 mg.
    GUM (Fruit and mint): 48, 204 x 2 mg; 48
    x 4 mg. 1 piece of gum on urge to
    smoke. Usually 8-12 pieces req. dly.
    Max: 25 pieces of 2 mg dly; 15 pieces of
    4 mg dly.
    Aid to smoking cessation.

    Nicotinell Lozenges
    partial basket chart
    Nicotinell Lozenges

    Alkaloid. Nicotine 1 mg, 2 mg.
    Lozenges: 36 x 1 mg, 2 mg. 1-2 loz. every
    1-2 hrs. Recommend: 8-12 loz dly. Max.
    30 x 1 mg/15 x 2 mg dly.
    For adults > 18 yrs. Aid to smoking
    cessation. Also as part of program to
    reduce smoking prior to stopping
    completely. 1 mg: for smokers of < 20
    cigarettes dly; 2 mg: for smokers of > 20
    cigarettes dly.
    C/I: Hypersens., non-smokers, <18 yrs,

    Selincro 18 mg
    not in the basket chart
    Selincro 18 mg

    Drugs used in Alcohol Dependence. Nalmefene 18.06 mg (as hydrochloride dihydrate).
    F.C. TABS: 14. Administ. should be adjust.
    individ, for each pt. accord. to its clin.
    status, alcohol depend., level of alcohol
    consump. Therap. must cont. under
    const. superv. of specialist.
    Max. Dose is 18.06 mg ×1/d, before or
    after meal.
    Reduc. of alcohol consump. in adult pts.
    with alcohol depend. who have a high DRL,
    without phys. withdrawal sympt. and who
    do not require immed. detoxif.
    Should only be used in conjunct.with
    contin. psychosoc. support focused on tmt.
    adherence and reduc. alcohol consump.
    Should be init. only in pts. who cont. to have a high DRL two weeks after init.
    C/I: Hypersens. Pts. taking opioid agon. (e.g. opioid analg., opioids for substit. ther. with
    opioid agon. (e.g. methadone) or part.
    agon. (e.g. buprenorphine). Pts. with curr., recent opioid addic. Pts. with acute sympt. of opioid withdrawal. Pts. suspect. in recent use of opioids. Sev. hep.impair. Sev. ren. impair. (eGFR<30 ml/min per 1.73 m²).
    Recent hist. of acute alcohol withdrawal
    synd. (include. hallucin. seiz., delir.

    partial basket chart
    Multiple ingredients

    Opiod Dependency. Buprenorphine 8.64 mg, Naloxone HCl 2.44 mg.
    S.L. TAB. 7, 28.
    The recommend. start. dose in adult.,
    adolesc. over 15 yrs.: 1-2 tabs. of 2
    mg/0.5 mg. An addit. 1-2 tabs. 2 mg/0.5
    mg may be administ. on day one
    depend. on the individ. pts. requirem.
    Dose titrat. in steps of 2-8 mg is guided
    by reassess. of the clinic. & psycholog.
    status of the pt., and should not exceed
    a max. single dly. dose of 24 mg.
    Substit. tmt. for opioid drug dependence,
    within a framework of med., social and
    psycholog. tmt. in adult., adolesc. over 15
    yrs. who have agreed to be treated for
    C/I: Hypersens., severe resp. insuffic.,
    severe hepat. impair, acute alcoholism or
    delirium tremens.

    not in the basket chart

    Partial Opioid Agonist/Antagonist. Buprenorphine (as HCl) 2 mg, 8 mg.
    TABS: 7 x 2 mg, 8 mg. See lit.
    Substitut. tmt. opioid depend. within
    framework of medical, social and
    psycholog. tmt.
    C/I: Hypersens., severe respir. insuffic.,
    severe hepat. insuffic., acute alcoholism.,
    delirium tremens, under 16 yrs., lact.