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  • Buprenorphine
    3 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Butrans
    Rafa
    RX
    partial basket chart
    Butrans

    Opioid. Buprenorphine 5, 10, 15, 20 mg.
    TRANSDERMAL 7-DAY MATRIX PATCHES:
    Butrans 5: 2 x 5 mg/patch (5 μg/hr);
    Butrans 10: 2 x 10 mg (10 μg/hr);
    Bytrans 15: 15 mg (15μg/hr);
    Butrans 20: 2 x 20 mg (20 μg/hr).
    Should be applied every 7 days.
    Not for acute pain. Patients aged 18 years and over: Initial: BuTrans 5,
    depend. opioid history, current gen.
    cond., medical status. Pts. should use
    usual recommend. doses of short-act.
    supplement. analgesics as needed
    until analgesic effecacy is attained.
    Titrat.: The dose may be titr. upwards as indic. after 3 d., when the max. effect of a
    given dose is establish. Subsequent dosage increases may then be titrated based on the need for supplem. pain relief and the pt’s. analges. response to the patch.
    To incr. the dose, a larger patch should replace the patch that is current. being
    worn, or a comb. of patches should be appl. in differ. places to achieve the
    desired dose. It is recom. that no more than two patches are appl. at the same
    time, up to (and includ.) a max. total dose of 40mcg/h. A new patch should not
    be appl. to the same skin site for the subseq.3-4 wks. See lit.
    Tmt. mod.-severe opioid respons. chron.
    pain conds. not adequat. respond. to
    non-opioid analges.
    C/I:
    Hypersens. Opioid depend. pts. and for narcotic withdrawal tmt. Condit. in which the respirat. centre and funct. are sever. impaired or may become so. Pts. who are receiving MAO inhib. or have taken them within the last 2 wks. Pts.suffer. from myasthenia g. Pts.suffer. from delirium tremens.

    Suboxone
    NSE
    RX
    partial basket chart
    Multiple ingredients
    Suboxone

    Opiod Dependency. Buprenorphine 8.64 mg, Naloxone HCl 2.44 mg.
    S.L. TAB. 7, 28.
    The recommend. start. dose in adult.,
    adolesc. over 15 yrs.: 1-2 tabs. of 2
    mg/0.5 mg. An addit. 1-2 tabs. 2 mg/0.5
    mg may be administ. on day one
    depend. on the individ. pts. requirem.
    Dose titrat. in steps of 2-8 mg is guided
    by reassess. of the clinic. & psycholog.
    status of the pt., and should not exceed
    a max. single dly. dose of 24 mg.
    Substit. tmt. for opioid drug dependence,
    within a framework of med., social and
    psycholog. tmt. in adult., adolesc. over 15
    yrs. who have agreed to be treated for
    addiction.
    C/I: Hypersens., severe resp. insuffic.,
    severe hepat. impair, acute alcoholism or
    delirium tremens.

    Subutex
    NSE
    RX
    not in the basket chart
    Subutex

    Partial Opioid Agonist/Antagonist. Buprenorphine (as HCl) 2 mg, 8 mg.
    TABS: 7 x 2 mg, 8 mg. See lit.
    Substitut. tmt. opioid depend. within
    framework of medical, social and
    psycholog. tmt.
    C/I: Hypersens., severe respir. insuffic.,
    severe hepat. insuffic., acute alcoholism.,
    delirium tremens, under 16 yrs., lact.

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