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  • Hypoglycemia
    12 Drugs classified under this therapeutic system

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    partial basket chart

    α-Gucosidase Inhibitor. Acarbose 50 mg, 100 mg.
    TABS: 30 x 50 mg, 100 mg. Initial: Wk 1:
    25 mg at dinner; wk 2: 25 mg at breakf.
    and dinner; wks 3-4: 25 mg at breakf.,
    lunch and dinner; wk 5: Incr. dose at
    dinner to 50 mg; wk 6: Also incr. dose
    at breakf. to 50 mg; wks 7-8: 50 mg at
    breakf., lunch, dinner. Aft. 8 wks: Eval.
    response and adjust accord. Wk 9: Incr.
    dose at dinner to 100 mg; wks 10-11:
    Also incr. dose at breakf. to 100 mg; wk
    12: 100 mg at breakf., lunch, dinner.
    Tab to chew./swallow. immed. at
    beginn. meal with 1st mouthful. If dose
    forgot: Take at next meal and not betw.
    NIDDM in pts. inad. control. by diet
    alone or on diet and oral hypoglycem.
    C/I: Hypersens., pregn., lact., chron.
    digest. syst. disords., liver funct. disords.,
    ren. insuffic. See lit.

    not in the basket chart
    Multiple ingredients

    Biguanide, DPP-4 Inhibitor. Vildagliptin 50 mg, Metformin Hydrochloride 500, 850, 1000 mg.
    F.C. TABS: 60 x Vildagliptin 50 mg/
    Metformin 500 mg; 60 x
    Vildagliptin 50 mg/Metformin 850 mg;
    Vildagliptin 50 mg/Metformin 1,000 mg.
    Based on the pt. current dose of
    Metformin, tmt. may be init. at either
    50 mg /500 mg or 50 mg/850 mg or 50
    mg/1000 mg tab. strength BID, one
    tab. in the morning and evening. Pts
    already receiving metformin +
    vildagliptin from separate tabs: switch
    to the equivalent combined tab. Daily
    doses >100 mg of vildagliptin are not
    recommend. See lit.
    Tmt. type 2 diabetes mellitus in adult pts.
    insuffic. controlled with max. tolerat.
    dose Metformin alone or already treat.
    with vildaliptin and Metformin as
    separate tabs. In comb. with a
    sulfonylurea as an adjunct to diet and
    exercise in adult pts. inadeq. controlled
    with metformin and a sulfonylurea. In
    triple comb. ther. with insulin as an
    adjunct to diet and exercise to improve
    glycaemic control in adult pts.when
    insulin at a stable dose and Metformin
    alone do not provide adeq. glycaemic
    C/I: Hypersens., Diab. ketoacid., diabet.
    pre-coma. Ren. fail. ,ren,dysfunc, (CrCl<
    60 ml/min) dehydr., sev. infec., shock.
    Intravasc. admin. of iod. contrast ag. Acute/ chron. dis. which may cause
    tissue hypox., (e.g: Card. fail.). Resp. fail.,
    recent MI, Hep. impair. Acute alcohol
    intox., alcoholism. Lact.

    Galvus 50 mg
    not in the basket chart
    Galvus 50 mg

    DPP-4 Inhibitor. Vildagliptin 50 mg.
    TABS: 7, 14, 28, 56.
    Dosage must be indivi. ajust. for each pt.
    Monotherpy: 50 mg x1 dly in the
    morning or 50 mg x 2 dly (morn.,even.).
    In combin. with other antidiabetics:
    see lit. Max 100 mg dly, with/out food.
    As adjunct to diet, exercise in type 2
    diabetes mellitus: As monother. if diet,
    exercise insuffic., or in combinat. with
    metformin or sulfonylurea if tmt. with
    these offers insuffic. control blood
    glucose. As triple ther. in combinat. with
    a sulphonylurea and metformin when
    diet, exercise plus dual therapy do not
    provide adequate glycaemic control.
    Comb. use with insulin (with/ without
    metformin) when diet, exercise plus a
    stable dose of insulin do not provide
    adequate glycaemic control. As an
    adjunct to diet and exercise in pts. with
    type 2 diabetes mellitus.In comb. with a
    thiazolidinedione, in pts. with insuffic.
    glycaemic control and for whom the use
    of a thiazolidinedione is appropriate.
    C/I: Hypesens.

    full basket chart

    Sulphonylurea. Glibenclamide 5 mg.
    TABS: 30, 100. The usual total dly.
    dosage is 2.5 mg- 15 mg dly. with a
    usual initial dose of 5 mg dly. Wkly.
    adjust. can be made to incr. the dosage
    to the opt. level. Doses of 10 mg or less
    may be taken as a single dose immed.
    before breakfast, but should the dly.
    dose exceed 10mg, the remainder
    should be taken immed. before the
    even. meal. The elder. usual. require
    lower dosage. See Lit. Second. dosage
    adjust.: See Lit.
    Control of hyperglycem. in stable, mild,
    nonketosis prone Glibenclamide
    responsive type II diabetes mell., which
    cannot be control.by proper dietary
    manag.or when insulin ther. is
    C/I: Hypersens. Pts. with hist./present
    diabetic ketoacidosis or diabetic coma/
    precoma, pts. who have insulin-depend.
    diabetes mell., serious impair. of renal,
    hepatic or adrenocortical funct.
    Circumstan. of unusual stress, e.g. surg.
    operations , during preg., when dietary
    measures and insulin are essential.
    Pts. with sulphonylurea or
    sulphonamide intoler., ‘Brittle’ or juvenile
    diab., preg., breast feed. women, child.,
    pts. treated with bosentan. See Lit.

    Glucagen Hypokit
    Novo Nordisk
    full basket chart
    Glucagen Hypokit

    Glycogenolytic Hormone. Glucagon (as HCl) 1 mg.
    SINGLE DOSE VIAL: 1 mg lyophylised
    biosynthetic pwdr. plus a sterile
    disposable syringe prefilled with 1 ml
    diluent of sterile water. See Lit.
    Tmt. severe hypoglycem. reacts which
    may occur in manage. insulin treated pts.
    with diabetes.

    partial basket chart

    Sulphonylurea. Glipizide 5 mg.
    TABS: 30. Initial 1/2-1 tab dly. bef. breakf.
    Adjust in increments of 2.5-5 mg. Max:
    40 mg dly.
    Maturity onset diabetes not manage. by
    diet alone.
    C/I: Diabet. ketoacidosis with/without
    coma, hypersens.

    Other therapeutic systems under Diabetes