All the Active Ingredient Drugs
Sulphonylurea. Glibenclamide 5 mg. TABS: 30, 100. The usual total dly.
dosage is 2.5 mg- 15 mg dly. with a
usual initial dose of 5 mg dly. Wkly.
adjust. can be made to incr. the dosage
to the opt. level. Doses of 10 mg or less
may be taken as a single dose immed.
before breakfast, but should the dly.
dose exceed 10mg, the remainder
should be taken immed. before the
even. meal. The elder. usual. require
lower dosage. See Lit. Second. dosage
adjust.: See Lit.
Control of hyperglycem. in stable, mild,
nonketosis prone Glibenclamide
responsive type II diabetes mell., which
cannot be control.by proper dietary
manag.or when insulin ther. is
C/I: Hypersens. Pts. with hist./present
diabetic ketoacidosis or diabetic coma/
precoma, pts. who have insulin-depend.
diabetes mell., serious impair. of renal,
hepatic or adrenocortical funct.
Circumstan. of unusual stress, e.g. surg.
operations , during preg., when dietary
measures and insulin are essential.
Pts. with sulphonylurea or
sulphonamide intoler., ‘Brittle’ or juvenile
diab., preg., breast feed. women, child.,
pts. treated with bosentan. See Lit.