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  • DPP-4 Inhibitor
    11 Drugs classified under this drug class


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    Eucreas
    Novartis
    RX
    not in the basket chart
    Multiple ingredients
    Eucreas

    Biguanide, DPP-4 Inhibitor. Vildagliptin 50 mg, Metformin Hydrochloride 500, 850, 1000 mg.
    F.C. TABS: 60 x Vildagliptin 50 mg/
    Metformin 500 mg; 60 x
    Vildagliptin 50 mg/Metformin 850 mg;
    Vildagliptin 50 mg/Metformin 1,000 mg.
    Based on the pt. current dose of
    Metformin, tmt. may be init. at either
    50 mg /500 mg or 50 mg/850 mg or 50
    mg/1000 mg tab. strength BID, one
    tab. in the morning and evening. Pts
    already receiving metformin +
    vildagliptin from separate tabs: switch
    to the equivalent combined tab. Daily
    doses >100 mg of vildagliptin are not
    recommend. See lit.
    Tmt. type 2 diabetes mellitus in adult pts.
    insuffic. controlled with max. tolerat.
    dose Metformin alone or already treat.
    with vildaliptin and Metformin as
    separate tabs. In comb. with a
    sulfonylurea as an adjunct to diet and
    exercise in adult pts. inadeq. controlled
    with metformin and a sulfonylurea. In
    triple comb. ther. with insulin as an
    adjunct to diet and exercise to improve
    glycaemic control in adult pts.when
    insulin at a stable dose and Metformin
    alone do not provide adeq. glycaemic
    control.
    C/I: Hypersens., Diab. ketoacid., diabet.
    pre-coma. Ren. fail. ,ren,dysfunc, (CrCl<
    60 ml/min) dehydr., sev. infec., shock.
    Intravasc. admin. of iod. contrast ag. Acute/ chron. dis. which may cause
    tissue hypox., (e.g: Card. fail.). Resp. fail.,
    recent MI, Hep. impair. Acute alcohol
    intox., alcoholism. Lact.

    Galvus
    Novartis
    RX
    not in the basket chart
    Galvus

    DPP-4 Inhibitor. Vildagliptin 50 mg.
    TABS: 7, 14, 28, 56.
    Dosage must be indivi. ajust. for each pt.
    Monotherpy: 50 mg x1 dly in the
    morning or 50 mg x 2 dly (morn.,even.).
    In combin. with other antidiabetics:
    see lit. Max 100 mg dly, with/out food.
    As adjunct to diet, exercise in type 2
    diabetes mellitus: As monother. if diet,
    exercise insuffic., or in combinat. with
    metformin or sulfonylurea if tmt. with
    these offers insuffic. control blood
    glucose. As triple ther. in combinat. with
    a sulphonylurea and metformin when
    diet, exercise plus dual therapy do not
    provide adequate glycaemic control.
    Comb. use with insulin (with/ without
    metformin) when diet, exercise plus a
    stable dose of insulin do not provide
    adequate glycaemic control. As an
    adjunct to diet and exercise in pts. with
    type 2 diabetes mellitus.In comb. with a
    thiazolidinedione, in pts. with insuffic.
    glycaemic control and for whom the use
    of a thiazolidinedione is appropriate.
    C/I: Hypesens.

    Glyxambi
    Boehringer Ingelheim
    RX
    not in the basket chart
    Multiple ingredients
    Glyxambi

    DPP-4 Inhibitor, SGLT2 Inhibitor. Empagliflozin 10, 25 mg, Linagliptin 5 mg.
    F.C.TABS.: 30. The recomm. dose of this drug is 10 mg empagliflozin/5 mg linagliptin once dly. in the morn., taken with/ without food. In pts. tolerat. this formul., the dose may be incr. to 25 mg empagliflozin/5 mg linagliptin once dly. See lit.
    Indic. as an adjunct to diet and exercise to improve glycem. control in adults with type 2 diab. mell. when tmt. with both empagliflozin and linagliptin is approp..
    C/I: Sev. ren. impair., end-stage renal dis., or dialysis. Hist. of hypersens. reaction to linagliptin, such as anaphylax., angioedema, exfoliative skin condit., urticaria, or bronch. hyperreactivity. Hist. of serious hypersens. reaction to empagliflozin.

    Januet 50/500 mg
    MSD
    RX
    not in the basket chart
    Multiple ingredients
    Januet 50/500 mg

    Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 500 mg, Sitagliptin 50 mg.
    TABS: 56. 2 x dly with meals. Graduate
    dosage to avoid GI side effects. Max.
    dly dose: 100 mg sitagliptin/2,000 mg
    metformin HCl.
    Adjunct to diet/excercise to improve
    glycemic control in type 2 diabetes
    mellitus, when tmt. with both sitagliptin
    and metformin approp. Not to be used in
    type 1 diabetes or tmt. diabet.
    ketoacidos. Not studied in history
    pancreatit. See lit.
    C/I: Ren. dis./dysfunct.; acute/chron.
    metabol. acidos. (incl. diabet. acidos.)
    with/out coma, hypersens., discont.
    when undergoing radiolog. studies
    involving IV admin. or iodinated contrast
    materials.

    Januet 50/850 mg
    MSD
    RX
    not in the basket chart
    Multiple ingredients
    Januet 50/850 mg

    Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 850 mg, Sitagliptin 50 mg.
    TABS: 56. 2 x dly with meals. Graduate
    dosage to avoid GI side effects. Max.
    dly dose: 100 mg sitagliptin/2,000 mg
    metformin HCl.
    Adjunct to diet/excercise to improve
    glycemic control in type 2 diabetes
    mellitus, when tmt. with both sitagliptin
    and metformin approp. Not to be used in
    type 1 diabetes or tmt. diabet.
    ketoacidos. Not studied in history
    pancreatit. See lit.
    C/I: Ren. dis./dysfunct.; acute/chron.
    metabol. acidos. (incl. diabet. acidos.)
    with/out coma, hypersens., discont.
    when undergoing radiolog. studies
    involving IV admin. or iodinated contrast
    materials.

    Januet XR
    MSD
    RX
    not in the basket chart
    Multiple ingredients
    Januet XR

    Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 1000 mg, 500 mg, Sitagliptin (as Phosphate Salt) 100 mg, 50 mg.
    TABS: 30, 60. Once dly with meals, pref. in
    the evening. Max. dly dose: 100 mg sitagliptin/2,000 mg metformin HCl.
    Adjunct to diet/exercise to improve
    glycemic control in adults with type 2
    diabetes mellitus, when tmt. with both
    sitagliptin and metformin ext. release is
    approp.
    C/I: Ren. impairm., acute/chron.
    metabol. acidos. (incl. diabet.
    ketoacidos.), hypersens. to metformin,
    history of hypersens. reaction to the
    product or sitagliptin.

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