Sitagliptin

6 Drugs classified under this active ingredient

Biguanide, DDP-4 Inhibitor. Metformin Hydrochloride 1,000 mg, Sitagliptin 50 mg.
TABS: 56. 2 x dly with meals. Graduate
dosage to avoid GI side effects. Max.
dly dose: 100 mg sitagliptin/2,000 mg
metformin HCl.
Adjunct to diet/excercise to improve
glycemic control in type 2 diabetes
mellitus, when tmt. with both sitagliptin
and metformin approp. Not to be used in
type 1 diabetes or tmt. diabet.
ketoacidos. Not studied in history
pancreatit. See lit.
C/I: Ren. dis./dysfunct.; acute/chron.
metabol. acidos. (incl. diabet. acidos.)
with/out coma, hypersens., discont.
when undergoing radiolog. studies
involving IV admin. or iodinated contrast
materials.

Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 500 mg, Sitagliptin 50 mg.
TABS: 56. 2 x dly with meals. Graduate
dosage to avoid GI side effects. Max.
dly dose: 100 mg sitagliptin/2,000 mg
metformin HCl.
Adjunct to diet/excercise to improve
glycemic control in type 2 diabetes
mellitus, when tmt. with both sitagliptin
and metformin approp. Not to be used in
type 1 diabetes or tmt. diabet.
ketoacidos. Not studied in history
pancreatit. See lit.
C/I: Ren. dis./dysfunct.; acute/chron.
metabol. acidos. (incl. diabet. acidos.)
with/out coma, hypersens., discont.
when undergoing radiolog. studies
involving IV admin. or iodinated contrast
materials.

Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 850 mg, Sitagliptin 50 mg.
TABS: 56. 2 x dly with meals. Graduate
dosage to avoid GI side effects. Max.
dly dose: 100 mg sitagliptin/2,000 mg
metformin HCl.
Adjunct to diet/excercise to improve
glycemic control in type 2 diabetes
mellitus, when tmt. with both sitagliptin
and metformin approp. Not to be used in
type 1 diabetes or tmt. diabet.
ketoacidos. Not studied in history
pancreatit. See lit.
C/I: Ren. dis./dysfunct.; acute/chron.
metabol. acidos. (incl. diabet. acidos.)
with/out coma, hypersens., discont.
when undergoing radiolog. studies
involving IV admin. or iodinated contrast
materials.

Biguanide, DPP-4 Inhibitor. Metformin Hydrochloride 1000 mg, 500 mg, Sitagliptin (as Phosphate Salt) 100 mg, 50 mg.
TABS: 30, 60. Once dly with meals, pref. in
the evening. Max. dly dose: 100 mg sitagliptin/2,000 mg metformin HCl.
Adjunct to diet/exercise to improve
glycemic control in adults with type 2
diabetes mellitus, when tmt. with both
sitagliptin and metformin ext. release is
approp.
C/I: Ren. impairm., acute/chron.
metabol. acidos. (incl. diabet.
ketoacidos.), hypersens. to metformin,
history of hypersens. reaction to the
product or sitagliptin.

DPP-4 Inhibitor. Sitagliptin 25, 50, 100 mg.
TABS: 28. Prior to initiat. ther: Assess
ren. funct. and period. thereaft. 100
mg 1 x dly with/out food. Mild ren. insuffic: No dose adjust necess. Mod.
ren. insuffic: 50 mg 1 x dly. Severe endstage
ren. defic. (ESRD)/peritoneal
dialysis: 25 mg 1 x dly without regard
to timing hemodialiys. In comb. with
sulfonylurea/insulin, use lower dose of
sulfonylurea/insulin.
Adjunct to diet/excercise to improve
glycemic control in type 2 diabetes
mellitus, Not to be used in type 1
diabetes or tmt. diabet. ketoacidos. Not
studied in history pancreatit. See lit.
C/I: History serious hypersens., such as
anaphylax., angiodema.

DPP-4 Inhibitor. Sitagliptin 25 mg, 50 mg, 100 mg.
FC tab 25, 50, 100 mg. Dosage for guid. only: 100 mg once dly.
See ptt's. leaflet
As an adjunct to diet and exercise to impr. glycemic
ctrol. in adults with type 2 diabetes mel. Import. limit. of use: Sitagliptin should not be used in ptts. with type 1 diabetes or for  tmt. of diabetic ketoacidosis as it would not be effective.Sitagliptin has not been studied in ptts. with a hist. of pancreat. It is unknown whether these ptts. are at incr. risk for the developm. of pancreat. while on this drug.
C/I:Hypersens.