DDP-4 Inhibitor

1 Drug classified under this drug class

Biguanide, DDP-4 Inhibitor. Metformin Hydrochloride 1,000 mg, Sitagliptin 50 mg.
TABS: 56. 2 x dly with meals. Graduate
dosage to avoid GI side effects. Max.
dly dose: 100 mg sitagliptin/2,000 mg
metformin HCl.
Adjunct to diet/excercise to improve
glycemic control in type 2 diabetes
mellitus, when tmt. with both sitagliptin
and metformin approp. Not to be used in
type 1 diabetes or tmt. diabet.
ketoacidos. Not studied in history
pancreatit. See lit.
C/I: Ren. dis./dysfunct.; acute/chron.
metabol. acidos. (incl. diabet. acidos.)
with/out coma, hypersens., discont.
when undergoing radiolog. studies
involving IV admin. or iodinated contrast
materials.