Asthma Prophylactics

12 Drugs classified under this therapeutic system

Monoclonal Antibody. Reslizumab 10 mg/ml.
VIAL(Concent. for sol.  for infus.): 1×10ml, 100ml. IV infus. only. Do not admin. as an IV push or bolus. The recomm. regimen is 3 mg/kg once every 4 wks. admin. by IV infus. over 20-50 min. Discont. the infus. immed. if the pt. experience. a sev. syst.  react., including anaphylaxis.
Indic. for the add-on mainten. tmt. of pts. with sev. asthma aged 18 yrs. and older with an eosinophilic phenotype.
C/I: Hypersens.

Corticosteroid. Fluticasone Propionate 0.5 mg / 2 ml, 2 mg/ 2 ml.
AMPS FOR NEBULIZAT: 2 ml x 0.5 mg, 2
mg. 500 μg-2,000 μg 2 x dly, adjust.
dose as reqd. Child and adolesc. from
4-16 yrs: 1,000 μg 2 x dly.
Proph. severe asth., tmt. acute exacerb.
asth. in adults, child. and adolesc. 4-16 yrs
and over.

Corticosteroid/Beta 2-Agonist. Beclometasone Dipropionate 200mcg/metered dose, Formoterol Fumarate 6mcg/metered dose.
INHALER. (Pressurised sol. for inhal).:1×120 actuation.
Adults 18 yrs. and above:
Two inhalations twice dly.
The max. dly. dose is 4 inhalat.
Foster 200/6 should be used as mainten. therapy only. A lower strength (Foster 100/6) is available for mainten. and reliever ther.
Indicated in the regular tmt. of asthma in adult. where use of a comb. product (inhaled corticosteroid and long-act. Β₂-ag.) is appropriate:
Pts. not adequate. control. with inhaled corticosteroids and 'as needed' inhaled rapid-acting Β2-agonist.
Pts. already adequat. controlled on both inhaled corticosteroids and long-act. Β2-ag. C/I: Hypersens.

Leukotriene Receptor Antagonist. Montelukast Sodium 4mg, 5mg.
Chew. Tabs.: 30. Adlt. 15 years and over with Asthma and/or Season. allergic rhinitis: 10 mg /d.
Ped. pts. 6 to 14 years old with Asthma and/or Season. allergic rhinitis: 5 mg/d. Ped. pts. 2 to 5 years old with Asthma and/or Season. allergic rhinitis: 4-mg/d.
Tabs 4 mg. in adlt. and ped. pts. aged 2 and over for the prophyl. and chron. tmt. of asthma, incl. prevent. of daytime and nighttime sympt., tmt. of aspirin-sensit. asthmatic pts., and  prevent. of exercise-induced bronchoconstrict. Effect. alone or in comb. with other agents used in the maint. tmt of chronic asthma. This drug and inh. corticost. may be used concom. with addit. effects to ctrol. asthma or reduce. the inhal. corticost. dose while maintaining clin. stability. For the relief of sympt. of season. allergic rhinitis in adlts and ped. pts. aged and over.
Tabs 5mg. for use by adlt. and ped. pts. aged 6 and over.
C/I:hypersens

Monoclonal Antibody. Mepolizumab 100 mg.
VIAL-1×10ml.: 100 mg SC once every 4 wks. Intended for long-term tmt. See lit.
Add-on tmt. for severe refract.  eosinophilic asthma in adult pts.
C/I: Hypersens.

Antihistamine. Ketotifen 1 mg / 5 ml.
SYR: 100 ml x 1 mg/ 5 ml. 6 mths- 3yrs:
1/2 teasp. 2 x dly. 3 yrs and over: 1
teasp. 2 x dly. with food.
Proph. tmt. allerg. conds. (allerg. bronchit.,
rhinit., hayfever, urticaria).
C/I: Babies under 6 mths, asth. attack.