Bronchial Spasm Relaxants

4 Drugs classified under this therapeutic system

Xanthine. Theophylline ethylenediamine 24 mg / ml.
AMP: 10 x 10 ml  for I.V. inj. Total dose should not exceed 0.8 ml/kg (equal to 5.6 mg of Aminophylline/kg).
Dosage must be individual.,
based on both symptom. respon. &
improv. in pulm. funct. See lit.
Bronchial asthma ;Pulmon. affect.
with bronchial spastic components.
C/I: Hypersens.
Ac. MI, hypotens. states, lact.

Xanthine. Theophylline Anhydrous 100 mg, 200 mg, 300 mg.
S.R. TABS: 30, 100 x 100 mg, 200 mg, 300
mg. 1 x 200 mg every 12 hrs. This may
be titrated to either 300-400 mg,
depends on therapy response.
Child: 9 mg/kg X 2dly. See lit
Asth., chron. bronchit., emphysema.

Selective β2 Agonist. Salbutamol (as sulfate) 0.5 mg/ml.
AMPS: 5 x 1 ml. S.C: 500 μg (8 μg/kg
bdy wt.) every 4-6 hrs as reqd; I.M: 500
μg (8 μg/kg bdy wt.) every 4-6 hrs as
reqd; I.V: 250 μg (4 μg/kg bdy wt.)
inject slowly.
Relief severe bronchosp., manage. status
asthmaticus.

Selective β2 Agonist. Salbutamol (as sulfate) 2 mg / 5 ml.
SYR: 150ml. Adults: 2-4 mg (5-10 ml ) x 3-4/dly. May be incr. to a max. of 8 mg (20ml) x 3-4 dly.
Child. : 2-6 yrs.: 1mg (2.5ml) x 3/dly.
May be incr. to 2mg (5ml) x 3-4/dly.
6-12 yrs: 2mg (5ml) x 3/dly. May be
incr. to 4 times dly.
>12 yrs.: 2mg (5ml) x 3/dly. May be
incr. to 4mg (10ml) x 3-4/dly.
Elderly. pts. or pts. with known sensit.
to β-adren. stim.: initiate tmt with min.
dose.
Relief of bronchospasm in bronchial
asthma of all types, chronic bronchitis,
efmphysema.
C/I: Hypersens., using this drug to arrest
uncomplicated premature labour or
threatened abortion.