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  • Spironolactone Teva
    / Teva


    Active Ingredient
    Spironolactone 25 mg, 100 mg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Tablets

    20 X 25 mg

    full basket chart 33902 19977

    Tablets

    20 X 100 mg

    full basket chart 33914 19978

    Dosage

    Hypertension: 50-100 mg daily.
    Edema: 25-200 mg daily in divided doses.
    Primary hyperaldosteronism: 400 mg daily in divided doses for 3-4 weeks. Hypokalemia: 25-100 mg daily.


    Indications

    Edema in patients with congestive heart failure, hepatic cirrhosis with edema, essential hypertension, hypokalemia, diagnosis of primary hyperaldosteronism.


    Contra-Indications

    Anuria, acute renal insufficiency, significant impairment of renal excretory function, or hyperkalemia.
    See prescribing information for full details.


    Special Precautions

    Potassium supplementation should not ordinarily be given in association with spironolactone. Pregnancy and lactation. Patient’s fluid and electrolyte balance should be carefully evaluated. Hyponatremia may be caused or aggravated, especially when spironolactone is administered in combination with other diuretics.
    See prescribing information for full details.


    Side Effects

    Gynecomastia. A few cases of agranulocytosis have been reported. Gastrointestinal symptoms, drowsiness, lethargy, headache and mental confusion, drug fever, ataxia, maculopapular or erythematous cutaneous eruptions, urticaria, inability to achieve or maintain erection, irregular menses or amenorrhea, postmenopausal bleeding, hirsutism and deepening of the voice, gastric bleeding, ulceration, gastritis and vomiting.
    See prescribing information for full details.


    Drug interactions

    See prescribing information for full details.


    Manufacturer
    Teva Pharmaceutical Industries Ltd, Israel
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