All the Active Ingredient Drugs
Aldosterone Antagonist. Spironolactone 25 mg. TABS: 20 x 25 mg. 50-100 mg dly.
Congest. card. fail. with oedema
For manag. of edema an init. dly. dose
of 100 mg of spironolactone admin. in
either single or divided doses is
recom., but may range from 25 mg-
200 mg dly. Mainten. dose should be
Pts. who tolerate 25 mg once dly. may
have their dose incr. to 50 mg×1/d. as
clinic. indic. Pts. who do not tolerate
25mg ×1/d may have their dose
reduced to 25 mg every other d.
Admin. with food.
Congest. heart fail; Cirrhot. ascites.
C/I: Acute renal insuffic. , signific. renal
compromise, anuria; Addison’s dis.;
Hyperkalaem.; Hypersens. to spironolactone.; Concom. use of
eplerenone or other K+ spar. diuret.;
Ped. pts. with moder.- sev. renal impair.;
Concom. use with other K+conserve.
diuret., K+supplem. should not be given
routin. with Aldactone as hyperkalaem.
may be induced.
Aldosterone Antagonist. Spironolactone 25 mg, 100 mg. TABS: 20 x 25 mg, 20 x 100 mg.
Hypertens: 50-100 mg dly. Ed: 25-200
mg dly. in div. doses. Prim.
hyperaldoster: 400 mg dly. in div.
doses for 3-4 wks; Hypokalem: 25-100
Ed. conds. in pts. with congest. heart fail.,
hepatic cirrhosis with ed., essential
hypertens., hypokalem, diagn. of prim.