All the Drug Class Drugs
Janus Kinase Inhibitor (JAKs). Tofacitinib 5 mg. F.C. TAB: 28, 60, 180. Rheum. Arthrit.: The drug may be used as monotherapy / in combin. with methotrexate or other non-biologic dis. modif. antirheum. drugs (DMARDs): 5 mg×2/d dly. oral. with/ without food.
Psoriat. Arthrit.: 5 mg×2/d dly. oral. with/ without food, used in comb. with non-biologic DMARDs.
The efficacy of Tofacitinib as a monother. has not been studied in psoriat. arthritis. See lit.
Indic. for the tmt. of adult. pts. with moderat. to sev. active RA who have had an inadeq. response or intolerance to methotrexate. It may be used as mono-ther. or in comb. with methotrexate /other non-biolog. DMARDs.
Limitations of Use: Use of Tofacitinib in comb. with biologic DMARDs or with potent immune-suppressant. such as azathioprine & cyclosporine is not recomm.
Psoriat. Arthrit.: Indicated for the tmt. of adult pts. with active psoriat. arthrit. who have had an inadeq. response or intoleran. to methotrexate or other DMARDs. Limitations of Use: Use of Tofacitinib in comb. with biologic DMARDs or with potent immune-suppressant. such as azathioprine & cyclosporine is not recomm.
C/I: Hypersens.
